Personal profile
Research interests
Professor Cass AO is the Director of Menzies School of Health Research (Menzies). Headquartered in Darwin, Menzies employs over 330 staff across Australia and the Asia Pacific region. Since opening its doors in 1985, Menzies core commitment has been to improving Indigenous health and wellbeing and addressing the highest priority health problems of communities across northern Australia and our region.
Having trained as a kidney specialist at Sydney University and Royal Prince Alfred Hospital, Prof Cass has pursued a research career with particular interest in the prevention and management of chronic disease and Indigenous health. His research has focused on developing, implementing and evaluating effective strategies to improve health outcomes. Prof Cass has a comprehensive understanding of health service delivery needs of Indigenous Australians. As a clinician, he has worked in a hands-on capacity providing care to patients and family members in urban, rural and remote settings. Prof Cass has been instrumental in leading the conduct of national and international clinical trials; conducting research to improve access to services and to improve provision of care to patients with low health literacy, who speak a different language and have different understandings of health and illness.
In 2020, Prof Cass was made an Officer (AO) of the Order of Australia for distinguished service to medical research, particularly to the prevention and management of chronic kidney disease, to improved Indigenous clinical care and health outcomes, and as a mentor.
Prof Cass has published more than 250 peer-reviewed papers and seminal reports for governments and NGOs. He was President of the Australia and New Zealand Society of Nephrology (2014-16), a founding Director of the Australian Clinical Trials Alliance (2012-17), and member of the Board of Top End Area Health Service (2015-17). He is Chair of the Advisory Board for the Australian Kidney Trials Network (AKTN), Chair of the National Advisory Committee for the ANZ Dialysis and Transplant Registry, and Deputy Chair of the NT Clinical Senate and a Council Member for the Central Australia Academic Health Science Network (CAAHSN).
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
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SDG 1 No Poverty
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SDG 3 Good Health and Well-being
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SDG 4 Quality Education
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SDG 5 Gender Equality
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SDG 8 Decent Work and Economic Growth
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SDG 9 Industry, Innovation, and Infrastructure
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SDG 10 Reduced Inequalities
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SDG 12 Responsible Consumption and Production
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SDG 13 Climate Action
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SDG 15 Life on Land
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SDG 16 Peace, Justice and Strong Institutions
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Collaborations and top research areas from the last five years
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2021 Rainmaker Start-up: Discovering the hidden rules and analytic expressions of machine learning models for kidney disease
De Boer, F. (Principal Investigator/Chief Investigator A), Azam, S. (Co Investigator/Chief Investigator B), Jonkman, M. (Chief Investigator C), Cass, A. (Chief Investigator D), Gorham, G. (Chief Investigator E) & Talukder, M. R. (Chief Investigator F)
18/11/21 → 18/10/22
Project: Research
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Acceptability and Effectiveness of the DESMOND diabetes self-management program for Indigenous Australians
Skinner, T. (Principal Investigator/Chief Investigator A), Mitchell, H. (Co Investigator/Chief Investigator B), Eades, S. (Chief Investigator C), Davis, T. (Chief Investigator D), Cass, A. (Chief Investigator E), Maple-Brown, L. (Chief Investigator F), Paul, C. (Chief Investigator G) & Barzi, F. (Chief Investigator H)
1/07/16 → 30/06/18
Project: Research
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An innovation platform for integrated quality improvement in Indigenous primary health care
Bailie, R. S. (Principal Investigator/Chief Investigator A), Askew, D. (Associate Investigator), Brown, A. (Associate Investigator), Clark, L. (Associate Investigator), Copley, K. (Associate Investigator), Hollins, A. (Associate Investigator), Kwedza, R. (Associate Investigator), McCalman, J. (Associate Investigator), Peiris, D. (Co Investigator/Chief Investigator B), Searles, A. (Associate Investigator), Tynan, M. (Associate Investigator), Wenitong, M. (Associate Investigator), Cunningham, F. (Chief Investigator C), Larkins, S. (Chief Investigator D), Doran, C. (Chief Investigator E), Cass, A. (Chief Investigator F), O'donoghue, L. R. (Chief Investigator G), Nelson, C. (Chief Investigator H), Burgess, P. (Chief Investigator I) & Tsey, K. (Chief Investigator J)
1/12/14 → 30/11/19
Project: Research
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APP1061767 NHMRC Improving the identification of depression in Aboriginal and Torres Strait Islander people
Hackett, M. (Principal Investigator/Chief Investigator A), Skinner, T. (Co Investigator/Chief Investigator B), Cass, A. (Chief Investigator C) & Askew, D. (Chief Investigator F)
1/01/14 → 31/12/16
Project: Research
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Centre for Research Excellence in Indigenous Child Health, Capability and Wellbeing
Silburn, S. (Principal Investigator/Chief Investigator A), Bailie, R. S. (Co Investigator/Chief Investigator B), Cass, A. (Co Investigator/Chief Investigator B), Guthridge, S. (Co Investigator/Chief Investigator B), Lynch, J. (Co Investigator/Chief Investigator B), McDonald, E. (Co Investigator/Chief Investigator B), Nossar, V. (Co Investigator/Chief Investigator B), Nutton, G. (Co Investigator/Chief Investigator B), Oberklaid, F. (Co Investigator/Chief Investigator B), Robinson, G. (Chief Investigator C), Senior, K. (Chief Investigator D), Singh, G. (Chief Investigator E), D'Aprano, A. (Chief Investigator F), Dunbar, T. E. (Chief Investigator G), Arney, F. (Chief Investigator H), Newman, L. (Chief Investigator I) & Mares, S. (Chief Investigator J)
1/11/13 → 31/10/18
Project: Research
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Climate preparedness in very remote desert communities - GNT2039696
Matthews, S. (Principal Investigator/Chief Investigator A), Cass, A. (Co Investigator/Chief Investigator B), Russell, D. (Chief Investigator C), Ford, L. (Co Investigator/Chief Investigator B), Ranse, J. (Chief Investigator C) & Vardoulakis, S. (Principal Investigator/Chief Investigator A)
16/06/25 → 31/12/29
Project: Research
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Determining the costs and benefits of dialysis services in urban, rural and remote settings – does place matter?
Cass, A. (Principal Investigator/Chief Investigator A) & Gorham, G. (Student Investigator)
27/05/13 → 31/03/21
Project: HDR Project › PhD
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A workforce enhancement model for Australian remote community Primary Health Care services: implementation of a stepped-wedge cluster randomised trial (SW-CRT)
Leach, A. J., McCullough, A., Websdale, E., Su, J. Y., Oguoma, V. M., Morris, P. S., Taylor, S., Nelson, S., Kong, K., Paterson, J., Dixon, J. & Cass, A., Jan 2026, In: BMC Health Services Research. 26, 1, p. 1-15 15 p., 289.Research output: Contribution to journal › Article › peer-review
Open AccessFile4 Downloads (Pure) -
Comparing different methods for analysing hierarchical composite endpoints: two illustrative case studies with post hoc analyses of the BALANCE (Bacteraemia Antibiotic Length Actually Needed for Clinical Effectiveness) and CAMERA2 (Combination Antibiotics for methicillin-resistant Staphylococcus aureus) randomized clinical trials
Ong, S. W. X., Pinto, R., Mahar, R. K., Petersiel, N., Fowler, R. A., Davis, J. S., Daneman, N., Tong, S. Y. C., Lye, D. C., Yahav, D., Sud, A., Robinson, J. O., Nelson, J., Archuleta, S., Roberts, M. A., Cass, A., Paterson, D. L., Foo, H., Paul, M. & Guy, S. D. & 117 others, , Feb 2026, In: Clinical Microbiology and Infection. 32, 3, p. 482-489 8 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile -
Effect of in vitro synergy and additivity of vancomycin or daptomycin plus an antistaphylococcal β-lactam for methicillin-resistant Staphylococcus aureus bacteraemia on mortality: preplanned analysis from CAMERA2
Soo, J. Z. Y., Lim, T. P., Ho, J. J. Y., Tong, S. Y. C., Lye, D. C., Davis, J. S., Kwa, A. L. H., Yahav, D., Sud, A., Owen Robinson, J., Nelson, J., Archuleta, S., Roberts, M. A., Cass, A., Paterson, D. L., Foo, H., Paul, M., Guy, S. D., Tramontana, A. R. & Walls, G. B. & 27 others, , Feb 2026, (E-pub ahead of print) In: Clinical Microbiology and Infection. p. 1-10 10 p.Research output: Contribution to journal › Article › peer-review
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Exploring adaptive capacity to arid heat in remote First Nations communities in Central Australia
Bhatta, M., Baliva, G., Pascoe, S., Talukder, M. R., Baghbanian, V., Russell, D., Ford, P. L., Cass, A., Wakerman, J. & Mathew, S., Feb 2026, In: Scientific Reports. 16, 1, p. 1-37 37 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile -
Haemodialysis catheter utilisation and factors associated with catheter-related bloodstream infection in Aotearoa New Zealand: Report from the binational, prospective, cluster-randomised trial
the REDUCCTION Investigators and Steering Committee, Jan 2026, In: Internal Medicine Journal. 56, 1, p. 72-82 11 p.Research output: Contribution to journal › Article › peer-review
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Association of Daily Body Temperature, White Blood Cell Count, and C-reactive Protein With Mortality and Persistent Bacteremia in Patients With Staphylococcus Aureus Bacteremia: A Post Hoc Analysis of the CAMERA2 Randomized Clinical Trial
CAMERA2 Study Group, 1 Feb 2025, In: Open Forum Infectious Diseases. 12, 2, p. 1-8 8 p., ofaf063.Research output: Contribution to journal › Article › peer-review
Open AccessFile3 Link opens in a new tab Citations (Scopus)23 Downloads (Pure) -
Cardiometabolic Biomarkers and Prediction of Kidney Disease Progression: The eGFR Cohort Study
Barr, E. L. M., Barzi, F., Mills, P., Nickels, M., Graham, S., Pearson, O., Obeyesekere, V., Hoy, W. E., Jones, G. R. D., Lawton, P. D., Brown, A. D. H., Thomas, M., Sinha, A., Cass, A., MacIsaac, R. J., Maple-Brown, L. J. & Hughes, J. T., Aug 2025, In: Canadian Journal of Kidney Health and Disease. 12, p. 1-11 11 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile1 Downloads (Pure)
Datasets
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Combination Antibiotic Therapy for Methicillin Resistant Staphylococcus Aureus infection (CAMERA2)
Davis, J. (Owner), Tong, S. (Creator), Lye, D. (Creator), Paterson, D. (Creator), Nelson, J. (Contributor), Roberts, M. (Creator), Cass, A. (Creator), Yahav, D. (Creator) & Archuleta, S. (Creator), Menzies School of Health Research, 2023
DOI: 10.25913/wjec-8n57, https://www.menzies.edu.au/page/Research/Projects/Staphylococcus/CAMERA_Clinical_Trial_Collection/
Dataset
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INFERR-Iron Infusion in Haemodialysis Primary Data
Majoni, S. W. (Creator) & Cass, A. (Creator), Menzies School of Health Research, 2026
DOI: 10.25913/5DS2-JN02, https://www.anzctr.org.au/Trial/Registration/TrialReview.aspx?id=378517&isReview=true
Dataset