Benedikt Ley

Research output

Research output per year 2008 2012 2017 2018 2019 2020 2022 2023

• 66 Article
• 4 Review article
• 2 Meeting Abstract
• 2 Comment/debate

Research output per year

Research output per year

Search results

• 2023

  Adapting international clinical trials during COVID-19 and beyond

  Thriemer, K., Degaga, T. S., Alam, M. S., Adhikari, B., Tripura, R., Hossain, M. S., Christian, M., Ghanchi, N. K., Mnjala, H., Weston, S., Ley, B., Rumaseb, A., Tadesse, D., Teferi, T., Yilma, D., Lee, G., Unger, H., Sutanto, I., Pasaribu, A. P., Ghimire, P., & 2 othersBeg, M. A. & Price, R. N., 11 Feb 2023, (E-pub ahead of print) In: Clinical Trials. p. 1-5 5 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File
  3 Downloads (Pure)

• Adherence to 14-day radical cure for Plasmodium vivax malaria in Papua, Indonesia: A mixed-methods study

  Rahmalia, A., Poespoprodjo, J. R., Landuwulang, C. U. R., Ronse, M., Kenangalem, E., Burdam, F. H., Thriemer, K., Devine, A., Price, R. N., Peeters Grietens, K., Ley, B. & Gryseels, C., 20 May 2023, In: Malaria Journal. 22, 1, p. 1-16 16 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

• Glucose-6-Phosphate Dehydrogenase (G6PD) Measurement Using Biosensors by Community-Based Village Malaria Workers and Hospital Laboratory Staff in Cambodia: A Quantitative Study

  Adhikari, B., Tripura, R., Dysoley, L., Peto, T. J., Callery, J. J., Heng, C., Vanda, T., Simvieng, O., Cassidy-Seyoum, S., Thriemer, K., Dondorp, A. M., Ley, B. & Seidlein, L. V., Mar 2023, In: Pathogens. 12, 3, p. 1-16 16 p., 400.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File
  1 Downloads (Pure)

• Primaquine-induced Severe Hemolysis in the Absence of Concomitant Malaria: Effects on G6PD Activity and Renal Function

  Douglas, N. M., Piera, K. A., Rumaseb, A., Ley, B., Anstey, N. M. & Price, R. N., 11 Jan 2023, In: The American journal of tropical medicine and hygiene. 108, 1, p. 76-80 5 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Hemolysis 100%
  • Primaquine 62%
  • Malaria 37%
  • Glucose 6 Phosphate Dehydrogenase 37%
  • Drug 25%
  16 Downloads (Pure)
• 2022

  A fluorometric assay to determine the protective effect of glucose-6-phosphate dehydrogenase (G6PD) against a Plasmodium spp. infection in females heterozygous for the G6PD gene: Proof of concept in Plasmodium falciparum

  Rumaseb, A., Marfurt, J., Kho, S., Kahn, M., Price, R. N. & Ley, B., 22 Feb 2022, In: BMC Research Notes. 15, 1, p. 1-4 4 p., 76.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Hemocyte 100%
  • Plasmodium 50%
  • Species 33%
  • Cells 33%
  • Schizont 33%
  6 Downloads (Pure)

• A molecular barcode and web-based data analysis tool to identify imported Plasmodium vivax malaria

  Trimarsanto, H., Amato, R., Pearson, R. D., Sutanto, E., Noviyanti, R., Trianty, L., Marfurt, J., Pava, Z., Echeverry, D. F., Lopera-Mesa, T. M., Montenegro, L. M., Tobón-Castaño, A., Grigg, M. J., Barber, B., William, T., Anstey, N. M., Getachew, S., Petros, B., Aseffa, A., Assefa, A., & 42 othersRahim, A. G., Chau, N. H., Hien, T. T., Alam, M. S., Khan, W. A., Ley, B., Thriemer, K., Wangchuck, S., Hamedi, Y., Adam, I., Liu, Y., Gao, Q., Sriprawat, K., Ferreira, M. U., Laman, M., Barry, A., Mueller, I., Lacerda, M. V. G., Llanos-Cuentas, A., Krudsood, S., Lon, C., Mohammed, R., Yilma, D., Pereira, D. B., Espino, F. E. J., Chu, C. S., Vélez, I. D., Namaik-larp, C., Villegas, M. F., Green, J. A., Koh, G., Rayner, J. C., Drury, E., Gonçalves, S., Simpson, V., Miotto, O., Miles, A., White, N. J., Nosten, F., Kwiatkowski, D. P., Price, R. N. & Auburn, S., 23 Dec 2022, In: Communications Biology. 5, 1, p. 1-10 10 p., 1411.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Single Nucleotide Polymorphism 100%
  • Plasmodium vivax 40%
  • Data Analysis 40%
  • Classification (Machine Learning) 40%
  • Learning 20%
  3 Downloads (Pure)

• An open dataset of Plasmodium vivax genome variation in 1,895 worldwide samples

  MalariaGEN, Adam, I., Alam, M. S., Alemu, S., Amaratunga, C., Amato, R., Andrianaranjaka, V., Anstey, N. M., Aseffa, A., Ashley, E., Assefa, A., Auburn, S., Barber, B. E., Barry, A., Batista Pereira, D., Cao, J., Chau, N. H., Chotivanich, K., Chu, C., Dondorp, A. M., & 59 othersDrury, E., Echeverry, D. F., Erko, B., Espino, F., Fairhurst, R., Faiz, A., Fernanda Villegas, M., Gao, Q., Golassa, L., Goncalves, S., Grigg, M. J., Hamedi, Y., Hien, T. T., Htut, Y., Johnson, K. J., Karunaweera, N., Khan, W., Krudsood, S., Kwiatkowski, D. P., Lacerda, M., Ley, B., Lim, P., Liu, Y., Llanos-Cuentas, A., Lon, C., Lopera-Mesa, T., Marfurt, J., Michon, P., Miotto, O., Mohammed, R., Mueller, I., Namaik-larp, C., Newton, P. N., Nguyen, T. N., Nosten, F., Noviyanti, R., Pava, Z., Pearson, R. D., Petros, B., Phyo, A. P., Price, R. N., Pukrittayakamee, S., Rahim, A. G., Randrianarivelojosia, M., Rayner, J. C., Rumaseb, A., Siegel, S. V., Simpson, V. J., Thriemer, K., Tobon-Castano, A., Trimarsanto, H., Urbano Ferreira, M., Vélez, I. D., Wangchuk, S., Wellems, T. E., White, N. J., William, T., Yasnot, M. F. & Yilma, D., 2022, In: Wellcome Open Research. 7, p. 1-22 22 p., 136.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Sample 100%
  • Genome Variation 60%
  • Plasmodium vivax 40%
  • Parasite 20%
  • Population Structure 20%
  3 Downloads (Pure)

• Field evaluation of the diagnostic performance of EasyScan GO: A digital malaria microscopy device based on machine-learning

  Das, D., Vongpromek, R., Assawariyathipat, T., Srinamon, K., Kennon, K., Stepniewska, K., Ghose, A., Sayeed, A. A., Faiz, M. A., Netto, R. L. A., Siqueira, A., Yerbanga, S. R., Ouédraogo, J. B., Callery, J. J., Peto, T. J., Tripura, R., Koukouikila-Koussounda, F., Ntoumi, F., Ong’echa, J. M., Ogutu, B., & 22 othersGhimire, P., Marfurt, J., Ley, B., Seck, A., Ndiaye, M., Moodley, B., Sun, L. M., Archasuksan, L., Proux, S., Nsobya, S. L., Rosenthal, P. J., Horning, M. P., McGuire, S. K., Mehanian, C., Burkot, S., Delahunt, C. B., Bachman, C., Price, R. N., Dondorp, A. M., Chappuis, F., Guérin, P. J. & Dhorda, M., Dec 2022, In: Malaria Journal. 21, 1, p. 1-12 12 p., 122.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Parasite 100%
  • Microscopy 85%
  • Microscope 71%
  • Malaria 42%
  • Density 42%
  5 Downloads (Pure)

• Genetic Variants of Glucose-6-Phosphate Dehydrogenase and Their Associated Enzyme Activity: A Systematic Review and Meta-Analysis

  Pfeffer, D. A., Satyagraha, A. W., Sadhewa, A., Alam, M. S., Bancone, G., Boum, Y., Brito, M., Cui, L., Deng, Z., Domingo, G. J., He, Y., Khan, W. A., Kibria, M. G., Lacerda, M., Menard, D., Monteiro, W., Pal, S., Parikh, S., Roca-Feltrer, A., Roh, M., & 6 othersSirdah, M. M., Wang, D., Huang, Q., Howes, R. E., Price, R. N. & Ley, B., Sep 2022, In: Pathogens. 11, 9, p. 1-18 18 p., 1045.

  Research output: Contribution to journal › Review article › peer-review

  Open Access

  File

  • Glucose 6 Phosphate Dehydrogenase 100%
  • Oxidoreductase 87%
  • Enzyme Activity 75%
  • Genetic Divergence 37%
  • Mutation 37%
  26 Downloads (Pure)

• Glucose 6 Phosphate Dehydrogenase (G6PD) quantitation using biosensors at the point of first contact: A mixed method study in Cambodia

  Adhikari, B., Tripura, R., Dysoley, L., Callery, J. J., Peto, T. J., Heng, C., Vanda, T., Simvieng, O., Cassidy-Seyoum, S., Ley, B., Thriemer, K., Dondorp, A. M. & von Seidlein, L., 4 Oct 2022, In: Malaria Journal. 21, 1, p. 1-15 15 p., 282.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Malaria 100%
  • Glucose 6 Phosphate Dehydrogenase 50%
  • Training 50%
  • Glucose-6-Phosphate Dehydrogenase 50%
  • Procedures 20%
  6 Downloads (Pure)

• Heterogeneity in prevalence of subclinical Plasmodium falciparum and Plasmodium vivax infections but no parasite genomic clustering in the Chittagong Hill Tracts, Bangladesh

  Huwe, T., Kibria, M. G., Johora, F. T., Phru, C. S., Jahan, N., Hossain, M. S., Khan, W. A., Price, R. N., Ley, B., Alam, M. S. & Koepfli, C., Dec 2022, In: Malaria Journal. 21, 1, p. 1-11 11 p., 218.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Prevalence 100%
  • Parasite 66%
  • Population Structure 66%
  • Plasmodium vivax 66%
  • Plasmodium falciparum 66%
  9 Downloads (Pure)

• Reducing the risk of Plasmodium vivax after falciparum infections in co-endemic areas—a randomized controlled trial (PRIMA)

  Thriemer, K., Degaga, T. S., Christian, M., Alam, M. S., Ley, B., Hossain, M. S., Kibria, M. G., Tego, T. T., Abate, D. T., Weston, S., Karahalios, A., Rajasekhar, M., Simpson, J. A., Rumaseb, A., Mnjala, H., Lee, G., Anose, R. T., Kidane, F. G., Woyessa, A., Baird, K., & 3 othersSutanto, I., Hailu, A. & Price, R. N., Dec 2022, In: Trials. 23, 1, p. 1-12 12 p., 416.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Incidence 100%
  • Parasitemia 80%
  • Malaria Falciparum 80%
  • Hemoglobin 80%
  • Randomized Controlled Trial 60%
  10 Downloads (Pure)

• Repeatability and reproducibility of a handheld quantitative G6PD diagnostic

  Ley, B., Winasti Satyagraha, A., Kibria, M. G., Armstrong, J., Bancone, G., Bei, A. K., Bizilj, G., Brito, M., Ding, X. C., Domingo, G. J., von Fricken, M. E., Gornsawun, G., Lam, B., Menard, D., Monteiro, W., Ongarello, S., Pal, S., Panggalo, L. V., Parikh, S., Pfeffer, D. A., & 8 othersPrice, R. N., da Silva Orfano, A., Wade, M., Wojnarski, M., Worachet, K., Yar, A., Alam, M. S. & Howes, R. E., 1 Feb 2022, In: PLoS Neglected Tropical Diseases. 16, 2, p. 1-17 17 p., e0010174.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Glucose 6 Phosphate Dehydrogenase 100%
  • Control 55%
  • Laboratory 44%
  • Spectrophotometry 44%
  • Diagnosis 33%
  38 Downloads (Pure)

• Safety of single-dose primaquine as a Plasmodium falciparum gametocytocide: A systematic review and meta-analysis of individual patient data

  Stepniewska, K., Allen, E. N., Humphreys, G. S., Poirot, E., Craig, E., Kennon, K., Yilma, D., Bousema, T., Guerin, P. J., White, N. J., Price, R. N., Raman, J., Martensson, A., Mwaiswelo, R. O., Bancone, G., Bastiaens, G. J. H., Bjorkman, A., Brown, J. M., D'Alessandro, U., Dicko, A. A., & 25 othersEl-Sayed, B., Elzaki, S. E., Eziefula, A. C., Gonçalves, B. P., Hamid, M. M. A., Kaneko, A., Kariuki, S., Khan, W., Kwambai, T. K., Ley, B., Ngasala, B. E., Nosten, F., Okebe, J., Samuels, A. M., Smit, M. R., Stone, W. J. R., Sutanto, I., Ter Kuile, F., Tine, R. C., Tiono, A. B., Drakeley, C. J., Gosling, R., Stergachis, A., Barnes, K. I. & Chen, I., Dec 2022, In: BMC Medicine. 20, 1, p. 1-19 19 p., 350.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Primaquine 100%
  • Hemoglobin 47%
  • Glucose 6 Phosphate Dehydrogenase 35%
  • Anemia 17%
  • Artemisinin 17%
  4 Downloads (Pure)

• Supervised versus unsupervised primaquine radical cure for the treatment of falciparum and vivax malaria in Papua, Indonesia: a cluster-randomised, controlled, open-label superiority trial

  Poespoprodjo, J. R., Burdam, F. H., Candrawati, F., Ley, B., Meagher, N., Kenangalem, E., Indrawanti, R., Trianty, L., Thriemer, K., Price, D. J., Simpson, J. A. & Price, R. N., Mar 2022, In: The Lancet Infectious Diseases. 22, 3, p. 367-376 10 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Primaquine 100%
  • Recurrent Disease 62%
  • Incidence 62%
  • Plasmodium Vivax Malaria 62%
  • Malaria Falciparum 50%

• Variation in Glucose-6-Phosphate Dehydrogenase activity following acute malaria

  Ley, B., Alam, M. S., Satyagraha, A. W., Phru, C. S., Thriemer, K., Tadesse, D., Shibiru, T., Hailu, A., Kibria, M. G., Hossain, M. S., Rahmat, H., Poespoprodjo, J. R., Khan, W. A., Simpson, J. A. & Price, R. N., 11 May 2022, In: PLoS Neglected Tropical Diseases. 16, 5, p. 1-15 15 p., e0010406.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Malaria 100%
  • Glucose 6 Phosphate Dehydrogenase 90%
  • Hemolysis 27%
  • Case-Control Study 27%
  • Cross Sectional Study 27%
  7 Downloads (Pure)
• 2021

  Diagnostic practices and treatment for P. vivax in the interethnic therapeutic encounter of South-Central Vietnam: A mixed-methods study

  Nguyen, T. T., Nguyen, X. X., Ronse, M., Nguyen, Q. T., Ho, P. Q., Tran, D. T., Gerrets, R., Thriemer, K., Ley, B., Marfurt, J., Price, R. N., Grietens, K. P. & Gryseels, C., Jan 2021, In: Pathogens. 10, 1, p. 1-20 20 p., 26.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Malaria 100%
  • Diagnosis 60%
  • Procedures 40%
  • Combination Therapy 40%
  • Drug Therapy 40%
  23 Downloads (Pure)

• Glucose-6-phosphate dehydrogenase activity in individuals with and without malaria: Analysis of clinical trial, cross-sectional and case–control data from Bangladesh

  Ley, B., Alam, M. S., Kibria, M. G., Marfurt, J., Phru, C. S., Ami, J. Q., Thriemer, K., Auburn, S., Jahan, N., Johora, F. T., Hossain, M. S., Koepfli, C., Khan, W. A. & Price, R. N., 23 Apr 2021, In: PLoS Medicine. 18, 4, p. 1-18 18 p., e1003576.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Glucose 6 Phosphate Dehydrogenase 100%
  • Malaria 92%
  • Cross Sectional Study 42%
  • Parasitemia 42%
  • Clinical Trial 42%
  32 Downloads (Pure)

• Implementing radical cure diagnostics for malaria: User perspectives on G6PD testing in Bangladesh

  Engel, N., Ghergu, C., Matin, M. A., Kibria, M. G., Thriemer, K., Price, R. N., Ding, X. C., Howes, R. E., Ley, B., Incardona, S. & Alam, M. S., 12 May 2021, In: Malaria Journal. 20, 1, p. 1-12 12 p., 217.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Malaria 100%
  • Patient 80%
  • Glucose 6 Phosphate Dehydrogenase 80%
  • Electric Potential 40%
  • Drug 40%
  19 Downloads (Pure)

• Towards the elimination of Plasmodium vivax malaria: Implementing the radical cure

  Thriemer, K., Ley, B. & von Seidlein, L., 23 Apr 2021, In: PLoS Medicine. 18, 4, p. 1-15 15 p., e1003494.

  Research output: Contribution to journal › Review article › peer-review

  Open Access

  File

  • Plasmodium Vivax Malaria 100%
  • Malaria 100%
  • Elimination 83%
  • Glucose 6 Phosphate Dehydrogenase 50%
  • Glucose-6-Phosphate Dehydrogenase 50%
  67 Downloads (Pure)
• 2020

  A novel generation of hemozoin based malaria diagnostics show promising performance

  Ley, B. & Thriemer, K., May 2020, In: EClinicalMedicine. 22, p. 1-2 2 p., 100369.

  Research output: Contribution to journal › Comment/debate › peer-review

  Open Access

  File

  • Generation 100%
  • Diagnostics 100%
  8 Downloads (Pure)

• Case Report: A Case of Primaquine-Induced Hemoglobinuria in Glucose-6-Phosphate Dehydrogenase Deficient Malaria Patient in Southeastern Bangladesh

  Phru, C. S., Kibria, M. G., Thriemer, K., Chowdhury, M. U., Jahan, N., Aktaruzzaman, M. M., Rahmat, H., Satyagraha, A. W., Prue, A. S., Khan, W. A., Ley, B. & Alam, M. S., 8 Jan 2020, In: The American Journal of Tropical Medicine and Hygiene . 102, 1, p. 156-158 3 p.

  Research output: Contribution to journal › Article › peer-review

  • Glucose 6 Phosphate Dehydrogenase 100%
  • Primaquine 75%
  • Malaria 50%
  • Chloroquine 25%
  • Case Report 25%

• Cost-effectiveness analysis of sex-stratified Plasmodium vivax treatment strategies using available G6PD diagnostics to accelerate access to radical cure

  Devine, A., Howes, R. E., Price, D. J., Moore, K. A., Ley, B., Simpson, J. A., Dittrich, S. & Price, R., Jul 2020, In: The American Journal of Tropical Medicine and Hygiene . 103, 1, p. 394-403 10 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Glucose 6 Phosphate Dehydrogenase 100%
  • Cost-Effectiveness Analysis 44%
  • Tafenoquine 44%
  • Health Care Cost 33%
  • Therapeutic Procedure 33%
  8 Downloads (Pure)

• High genetic similarity between non-typhoidal Salmonella isolated from paired blood and stool samples of children in the Democratic Republic of the Congo

  Phoba, M. F., Barbé, B., Ley, B., Van Puyvelde, S., Post, A., Mattheus, W., Deborggraeve, S., Lunguya, O. & Jacobs, J., Jul 2020, In: PLoS Neglected Tropical Diseases. 14, 7, p. 1-15 15 p., e0008377.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Salmonella 100%
  • Genetic Similarity 31%
  • Sample 12%
  • Serotype 12%
  • Excretion 12%
  5 Downloads (Pure)

• Precarity at the margins of malaria control in the chittagong hill tracts in bangladesh: A mixed-methods study

  Matin, M. A., Sarkar, N. D. P., Phru, C. S., Ley, B., Thriemer, K., Price, R. N., Grietens, K. P., Khan, W. A., Alam, M. S. & Gryseels, C., Oct 2020, In: Pathogens. 9, 10, p. 1-19 19 p., 840.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Malaria 100%
  • Patient 60%
  • Elimination 40%
  • Procedures 20%
  • Health Care Facility 20%
  16 Downloads (Pure)

• Quantification of glucose-6-phosphate dehydrogenase activity by spectrophotometry: A systematic review and meta-analysis

  Pfeffer, D. A., Ley, B., Howes, R. E., Adu, P., Alam, M. S., Bansil, P., Boum, Y., Brito, M., Charoenkwan, P., Clements, A., Cui, L., Deng, Z., Egesie, O. J., Espino, F. E., von Fricken, M. E., Hamid, M. M. A., He, Y., Henriques, G., Khan, W. A., Khim, N., & 26 othersKim, S., Lacerda, M., Lon, C., Mekuria, A. H., Menard, D., Monteiro, W., Nosten, F., Oo, N. N., Pal, S., Palasuwan, D., Parikh, S., Pitaloka Pasaribu, A., Poespoprodjo, J. R., Price, D. J., Roca-Feltrer, A., Roh, M. E., Saunders, D. L., Spring, M. D., Sutanto, I., Ley-Thriemer, K., Weppelmann, T. A., von Seidlein, L., Satyagraha, A. W., Bancone, G., Domingo, G. J. & Price, R. N., 1 May 2020, In: PLoS Medicine. 17, 5, p. 1-18 18 p., e1003084.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Glucose-6-Phosphate Dehydrogenase 100%
  • Glucose 6 Phosphate Dehydrogenase 88%
  • Hemoglobin 41%
  • Hemoglobins 41%
  • Assay 35%
  163 Downloads (Pure)

• Wide range of G6PD activities found among ethnic groups of the Chittagong Hill Tracts, Bangladesh

  Ley, B., Kibria, M. G., Khan, W. A., Auburn, S., Phru, C. S., Jahan, N., Johora, F. T., Thriemer, K., Ami, J. Q., Hossain, M. S., Price, R. N., Koepfli, C. & Alam, M. S., 1 Sep 2020, In: PLoS Neglected Tropical Diseases. 14, 9, p. 1-15 15 p., e0008697.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Glucose-6-Phosphate Dehydrogenase 100%
  • Glucose 6 Phosphate Dehydrogenase 93%
  • Malaria 46%
  • 8-Aminoquinoline 26%
  • Glucose 6 Phosphate Dehydrogenase Deficiency 26%
  16 Downloads (Pure)
• 2019

  Analysis of erroneous data entries in paper based and electronic data collection

  Ley, B., Rijal, K. R., Marfurt, J., Adhikari, N. R., Banjara, M. R., Shrestha, U. T., Thriemer, K., Price, R. N. & Ghimire, P., 22 Aug 2019, In: BMC Research Notes. 12, 1, p. 1-6 6 p., 537.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Data Collection 100%
  • Variables 83%
  • Electronic Data 66%
  • Categorical Variable 33%
  • Error 33%
  28 Downloads (Pure)

• Multicountry Distribution and Characterization of Extended-spectrum β-Lactamase-associated Gram-negative Bacteria from Bloodstream Infections in Sub-Saharan Africa

  Toy, T., Pak, G. D., Duc, T. P., Campbell, J. I., El Tayeb, M. A., Von Kalckreuth, V., Im, J., Panzner, U., Cruz Espinoza, L. M., Eibach, D., Dekker, D. M., Park, S. E., Jeon, H. J., Konings, F., Mogeni, O. D., Cosmas, L., Bjerregaard-Andersen, M., Gasmelseed, N., Hertz, J. T., Jaeger, A., & 30 othersKrumkamp, R., Ley, B., Thriemer, K., Kabore, L. P., Niang, A., Raminosoa, T. M., Sampo, E., Sarpong, N., Soura, A., Owusu-Dabo, E., Teferi, M., Yeshitela, B., Poppert, S., May, J., Kim, J. H., Chon, Y., Park, J. K., Aseffa, A., Breiman, R. F., Schütt-Gerowitt, H., Aaby, P., Adu-Sarkodie, Y., Crump, J. A., Rakotozandrindrainy, R., Meyer, C. G., Sow, A. G., Clemens, J. D., Wierzba, T. F., Baker, S. & Marks, F., 30 Oct 2019, In: Clinical Infectious Diseases. 69, Supplement_6, p. S449-S458 10 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Extended Spectrum Beta Lactamase 100%
  • Pathogen 42%
  • Bloodstream Infection 42%
  • Penicillinase 42%
  • Antibiotic Resistance 42%
  7 Downloads (Pure)

• Performance of the Access Bio/CareStart rapid diagnostic test for the detection of glucose-6-phosphate dehydrogenase deficiency: A systematic review and meta-analysis

  Ley, B., Winasti Satyagraha, A., Rahmat, H., von Fricken, M. E., Douglas, N. M., Pfeffer, D. A., Espino, F., von Seidlein, L., Henriques, G., Oo, N. N., Menard, D., Parikh, S., Bancone, G., Karahalios, A. & Price, R. N., 1 Dec 2019, In: PLoS Medicine. 16, 12, p. 1-15 15 p., e1002992.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Spectrophotometry 100%
  • Glucose-6-Phosphate Dehydrogenase Deficiency 75%
  • Malaria Rapid Test 75%
  • Glucose 6 Phosphate Dehydrogenase Deficiency 75%
  • Therapeutic Procedure 50%
  7 Downloads (Pure)

• Short-course primaquine for the radical cure of Plasmodium vivax malaria: a multicentre, randomised, placebo-controlled non-inferiority trial

  Taylor, W. R. J., Thriemer, K., von Seidlein, L., Yuentrakul, P., Assawariyathipat, T., Assefa, A., Auburn, S., Chand, K., Chau, N. H., Cheah, P. Y., Dong, L. T., Dhorda, M., Degaga, T. S., Devine, A., Ekawati, L. L., Fahmi, F., Hailu, A., Hasanzai, M. A., Hien, T. T., Khu, H., & 25 othersLey, B., Lubell, Y., Marfurt, J., Mohammad, H., Moore, K. A., Naddim, M. N., Pasaribu, A. P., Pasaribu, S., Promnarate, C., Rahim, A. G., Sirithiranont, P., Solomon, H., Sudoyo, H., Sutanto, I., Thanh, N. V., Tuyet-Trinh, N. T., Waithira, N., Woyessa, A., Yamin, F. Y., Dondorp, A., Simpson, J. A., Baird, J. K., White, N. J., Day, N. P. & Price, R. N., 14 Sep 2019, In: The Lancet. 394, 10202, p. 929-938 10 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Primaquine 100%
  • Plasmodium Vivax Malaria 60%
  • Placebo 40%
  • Recurrent Disease 30%
  • Incidence 30%
  4 Downloads (Pure)

• Supporting evidence for a human reservoir of invasive non-Typhoidal Salmonella from household samples in Burkina Faso

  Post, A. S., Diallo, S. N., Guiraud, I., Lompo, P., Tahita, M. C., Maltha, J., Van Puyvelde, S., Mattheus, W., Ley, B., Thriemer, K., Rouamba, E., Derra, K., Deborggraeve, S., Tinto, H. & Jacobs, J., 14 Oct 2019, In: PLoS Neglected Tropical Diseases. 13, 10, p. 1-18 18 p., e0007782.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Household 100%
  • Salmonella 26%
  • Sample 23%
  • Serotype 19%
  • Child 15%
  42 Downloads (Pure)

• The assessment of gestational age: A comparison of different methods from a malaria pregnancy cohort in sub-Saharan Africa 11 Medical and Health Sciences 1114 Paediatrics and Reproductive Medicine

  Unger, H., Thriemer, K., Ley, B., Tinto, H., Traoré, M., Valea, I., Tagbor, H., Antwi, G., Gbekor, P., Nambozi, M., Kabuya, J. B. B., Mulenga, M., Mwapasa, V., Chapotera, G., Madanitsa, M., Rulisa, S., De Crop, M., Claeys, Y., Ravinetto, R. & D'Alessandro, U., 8 Jan 2019, In: BMC Pregnancy and Childbirth. 19, 1, 12.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Gestational Age 100%
  • Fundal Height 85%
  • Woman 85%
  • Menstrual Cycle 71%
  • Procedures 71%
  21 Downloads (Pure)

• The haematological consequences of Plasmodium vivax malaria after chloroquine treatment with and without primaquine: a WorldWide Antimalarial Resistance Network systematic review and individual patient data meta-analysis

  Commons, R. J., Simpson, J. A., Thriemer, K., Chu, C. S., Douglas, N. M., Abreha, T., Alemu, S. G., Añez, A., Anstey, N. M., Aseffa, A., Assefa, A., Awab, G. R., Baird, J. K., Barber, B. E., Borghini-Fuhrer, I., D'Alessandro, U., Dahal, P., Daher, A., de Vries, P. J., Erhart, A., & 32 othersGomes, M. S. M., Grigg, M. J., Hwang, J., Kager, P. A., Ketema, T., Khan, W. A., Lacerda, M. V. G., Leslie, T., Ley, B., Lidia, K., Monteiro, W. M., Pereira, D. B., Phan, G. T., Phyo, A. P., Rowland, M., Saravu, K., Sibley, C. H., Siqueira, A. M., Stepniewska, K., Taylor, W. R. J., Thwaites, G., Tran, B. Q., Hien, T. T., Vieira, J. L. F., Wangchuk, S., Watson, J., William, T., Woodrow, C. J., Nosten, F., Guerin, P. J., White, N. J. & Price, R. N., 1 Aug 2019, In: BMC Medicine. 17, p. 1-13 13 p., 151.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Hemoglobin 100%
  • Time 50%
  • Taxonomy 50%
  • Plasmodium vivax 50%
  • Patient Coding 50%
  17 Downloads (Pure)
• 2018

  Comparison of glucose-6 phosphate dehydrogenase status by fluorescent spot test and rapid diagnostic test in Lao PDR and Cambodia

  Henriques, G., Phommasone, K., Tripura, R., Peto, T. J., Raut, S., Snethlage, C., Sambo, I., Sanann, N., Nguon, C., Adhikari, B., Pongvongsa, T., Imwong, M., Von Seidlein, L., Day, N. P., White, N. J., Dondorp, A. M., Newton, P., Ley, B. & Mayxay, M., 22 Jun 2018, In: Malaria Journal. 17, p. 1-7 7 p., 243.

  Research output: Contribution to journal › Review article › peer-review

  Open Access

  File

  • Rapid Diagnostic Test 100%
  • Glucose 6 Phosphate Dehydrogenase 87%
  • Sensitivity and Specificity 25%
  • Primaquine 25%
  • Spectrophotometry 25%
  68 Downloads (Pure)

• Field evaluation of quantitative point of care diagnostics to measure glucose-6-phosphate dehydrogenase activity

  Alam, M. S., Kibria, M. G., Jahan, N., Thriemer, K., Hossain, M. S., Douglas, N. M., Phru, C. S., Khan, W. A., Price, R. N. & Ley, B., 2 Nov 2018, In: PLoS One. 13, 11, p. 1-13 13 p., e0206331.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Glucose-6-Phosphate Dehydrogenase 100%
  • Glucose 6 Phosphate Dehydrogenase 88%
  • Sample 55%
  • Spectrophotometry 33%
  • Rose 11%
  27 Downloads (Pure)

• Low risk of recurrence following artesunate-Sulphadoxine-pyrimethamine plus primaquine for uncomplicated Plasmodium falciparum and Plasmodium vivax infections in the Republic of the Sudan

  Hamid, M. M. A., Thriemer, K., Elobied, M. E., Mahgoub, N. S., Boshara, S. A., Elsafi, H. M. H., Gumaa, S. A., Hamid, T., Abdelbagi, H., Basheir, H. M., Marfurt, J., Chen, I., Gosling, R., Price, R. N. & Ley, B., 16 Mar 2018, In: Malaria Journal. 17, 1, p. 1-14 14 p., 117.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Arm 100%
  • Dose 75%
  • Primaquine 75%
  • Polymerase Chain Reaction 50%
  • Malaria 50%
  23 Downloads (Pure)

• Quantifying primaquine effectiveness and improving adherence: A round table discussion of the APMEN Vivax Working Group

  Thriemer, K., Bobogare, A., Ley, B., Gudo, C. S., Alam, M. S., Anstey, N. M., Ashley, E., Baird, J. K., Gryseels, C., Jambert, E., Lacerda, M., Laihad, F., Marfurt, J., Pasaribu, A. P., Poespoprodjo, J. R., Sutanto, I., Taylor, W. R., Van Den Boogaard, C., Battle, K. E., Dysoley, L., & 78 othersGhimire, P., Hawley, B., Hwang, J., Khan, W. A., Mudin, R. N. B., Sumiwi, M. E., Ahmed, R., Aktaruzzaman, M. M., Awasthi, K. R., Bardaji, A., Bell, D., Boaz, L., Burdam, F. H., Chandramohan, D., Cheng, Q., Chindawongsa, K., Culpepper, J., Das, S., Deray, R., Desai, M., Domingo, G., Duoquan, W., Duparc, S., Floranita, R., Gerth-Guyette, E., Howes, R. E., Hugo, C., Jagoe, G., Sariwati, E., Jhora, S. T., Jinwei, W., Karunajeewa, H., Kenangalem, E., Lal, B. K., Landuwulang, C., Le Perru, E., Lee, S. E., Makita, L. S., McCarthy, J., Mekuria, A., Mishra, N., Naket, E., Nambanya, S., Nausien, J., Duc, T. N., Thi, T. N., Noviyanti, R., Pfeffer, D., Qi, G., Rahmalia, A., Rogerson, S., Samad, I., Sattabongkot, J., Satyagraha, A., Shanks, D., Sharma, S. N., Sibley, C. H., Sungkar, A., Syafruddin, D., Talukdar, A., Tarning, J., Ter Kuile, F., Thapa, S., Theodora, M., Huy, T. T., Waramin, E., Waramori, G., Woyessa, A., Wongsrichanalai, C., Xa, N. X., Yeom, J. S., Hermawan, L., Devine, A., Nowak, S., Jaya, I., Supargiyono, S., Grietens, K. P. & Price, R. N., 20 Jun 2018, In: Malaria Journal. 17, p. 1-7 7 p., 241.

  Research output: Contribution to journal › Meeting Abstract › peer-review

  Open Access

  File

  • Effectiveness 100%
  • Malaria 100%
  • Approach 75%
  • Primaquine 75%
  • Understanding 50%
  25 Downloads (Pure)

• Spectrophotometry assays to determine G6PD activity from Trinity Biotech and Pointe Scientific G6PD show good correlation

  Alam, M. S., Kibria, M. G., Jahan, N., Price, R. N. & Ley, B., 4 Dec 2018, In: BMC Research Notes. 11, 1, p. 1-4 4 p., 855.

  Research output: Contribution to journal › Comment/debate › peer-review

  Open Access

  • Assay 100%
  • Glucose 6 Phosphate Dehydrogenase 71%
  • Spectrophotometry 28%
  • Sample 14%
  • Student T Test 14%

• The effect of chloroquine dose and primaquine on Plasmodium vivax recurrence: A WorldWide Antimalarial Resistance Network systematic review and individual patient pooled meta-analysis

  Commons, R. J., Simpson, J. A., Thriemer, K., Humphreys, G. S., Abreha, T., Alemu, S. G., Añez, A., Anstey, N. M., Awab, G. R., Baird, J. K., Barber, B. E., Borghini-Fuhrer, I., Chu, C. S., D'Alessandro, U., Dahal, P., Daher, A., de Vries, P. J., Erhart, A., Gomes, M. S. M., Gonzalez-Ceron, L., & 34 othersGrigg, M. J., Heidari, A., Hwang, J., Kager, P. A., Ketema, T., Khan, W. A., Lacerda, M. V. G., Leslie, T., Ley, B., Lidia, K., Monteiro, W. M., Nosten, F., Pereira, D. B., Phan, G. T., Phyo, A. P., Rowland, M., Saravu, K., Sibley, C. H., Siqueira, A. M., Stepniewska, K., Sutanto, I., Taylor, W. R. J., Thwaites, G., Tran, B. Q., Tran, H. T., Valecha, N., Vieira, J. L. F., Wangchuk, S., William, T., Woodrow, C. J., Zuluaga-Idarraga, L., Guerin, P. J., White, N. J. & Price, R. N., 1 Sep 2018, In: The Lancet Infectious Diseases. 18, 9, p. 1025-1034 10 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Chloroquine 100%
  • Recurrent Disease 70%
  • Primaquine 60%
  • Dose 50%
  • Plasmodium Vivax Malaria 30%

• Therapeutic response to dihydroartemisinin-piperaquine for P. falciparum and P. Vivax nine years after its introduction in southern Papua, Indonesia

  Poespoprodjo, J. R., Kenangalem, E., Wafom, J., Chandrawati, F., Puspitasari, A. M., Ley, B., Trianty, L., Korten, Z., Surya, A. S., Syafruddin, D., Anstey, N., Marfurt, J., Noviyanti, R. & Price, R., Mar 2018, In: American Journal of Tropical Medicine and Hygiene. 98, 3, p. 677-682 6 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Patient 100%
  • Malaria 42%
  • Plasmodium Vivax Malaria 42%
  • Analysis 28%
  • Therapeutic Procedure 28%
  24 Downloads (Pure)
• 2017

  A comparison of three quantitative methods to estimate G6PD activity in the chittagong hill tracts, Bangladesh

  Ley, B., Alam, M. S., O'Donnell, J. J., Hossain, M. S., Kibria, M. G., Jahan, N., Ali Khan, W., Ley-Thriemer, K., Chatfield, M. D., Price, R. N. & Richards, J. S., 1 Jan 2017, In: PLoS One. 12, 1, p. 1-13 13 p., e0169930.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Development 100%
  • Hemoglobin 100%
  • Cross Sectional Study 100%
  • Ultraviolet Spectrophotometry 100%
  • Quantitative Technique 100%
  59 Downloads (Pure)

• Barriers to routine G6PD testing prior to treatment with primaquine

  Ley, B., Thriemer, K., Jaswal, J., Poirot, E., Alam, M. S., Phru, C. S., Khan, W. A., Dysoley, L., Qi, G., Kheong, C. C., Shamsudin, U. K., Chen, I., Hwang, J., Gosling, R. & Price, R. N., 10 Aug 2017, In: Malaria Journal. 16, p. 1-10 10 p., 329.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Primaquine 100%
  • Glucose 6 Phosphate Dehydrogenase 100%
  • Therapeutic Procedure 75%
  • Glucose-6-Phosphate Dehydrogenase Deficiency 75%
  • Plasmodium Vivax Malaria 75%
  17 Downloads (Pure)

• Challenges for achieving safe and effective radical cure of Plasmodium vivax: A round table discussion of the APMEN Vivax Working Group

  Thriemer, K., Ley, B., Bobogare, A. B., Dysoley, L., Alam, M. S., Pasaribu, A. P., Sattabongkot-Prachumsri, J. S. P., Jambert, E., Domingo, G. J., Commons, R., Auburn, S., Marfurt, J., Devine, A., Aktaruzzaman, M. M., Sohel, N., Namgay, R. N., Drukpa, T., Sharma, S. N., Sarawati, E., Samad, I., & 47 othersTheodora, M., Nambanya, S., Ounekham, S., Mudin, R. N. B., Da Thakur, G., Makita, L. S., Deray, R., Lee, S. E., Boaz, L., Danansuriya, M. N., Mudiyanselage, S. D., Chinanonwait, N., Kitchakarn, S., Nausien, J., Naket, E., Duc, T. N., Do Manh, H., Hong, Y. S., Cheng, Q., Richards, J. S., Kusriastuti, R., Satyagraha, A. W., Noviyanti, R., Ding, X. C., Khan, W. A., Swe Phru, C., Guoding, Z., Qi, G., Kaneko, A., Miotto, O., Nguitragool, W., Roobsoong, W., Battle, K., Howes, R. E., Roca-Feltrer, A., Duparc, S., Bhowmick, I. P., Kenangalem, E., Bibit, J. A., Barry, A. E., Sintasath, D., Abeyasinghe, R., Sibley, C. H., McCarthy, J., Von Seidlein, L., Baird, J. K. & Price, R. N., 5 Apr 2017, In: Malaria Journal. 16, 141, p. 1-9 9 p., 141.

  Research output: Contribution to journal › Meeting Abstract › peer-review

  Open Access

  File

  • Glucose 6 Phosphate 100%
  • Phosphorus Deficiency 100%
  • Primaquine 37%
  • Tafenoquine 37%
  • Therapeutic Procedure 25%
  17 Downloads (Pure)

• Incidence of invasive salmonella disease in sub-Saharan Africa: A multicentre population-based surveillance study

  Marks, F., von Kalckreuth, V., Aaby, P., Adu-Sarkodie, Y., El Tayeb, M. A., Ali, M., Aseffa, A., Baker, S., Biggs, H. M., Bjerregaard-Andersen, M., Breiman, R. F., Campbell, J. I., Cosmas, L., Crump, J. A., Espinoza, L. M. C., Deerin, J. F., Dekker, D. M., Fields, B. S., Gasmelseed, N., Hertz, J. T., & 39 othersVan Minh Hoang, N., Im, J., Jaeger, A., Jeon, H. J., Kabore, L. P., Keddy, K. H., Konings, F., Krumkamp, R., Ley, B., Løfberg, S. V., May, J., Meyer, C. G., Mintz, E. D., Montgomery, J. M., Niang, A. A., Nichols, C., Olack, B., Pak, G. D., Panzner, U., Park, J. K., Park, S. E., Rabezanahary, H., Rakotozandrindrainy, R., Raminosoa, T. M., Razafindrabe, T. J. L., Sampo, E., Schütt-Gerowitt, H., Sow, A. G., Sarpong, N., Seo, H. J., Sooka, A., Soura, A. B., Tall, A., Teferi, M., Thriemer, K., Warren, M. R., Yeshitela, B., Clemens, J. D. & Wierzba, T. F., 1 Mar 2017, In: The Lancet Global Health. 5, 3, p. e310-e323 14 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Salmonella 100%
  • Diseases 70%
  • Incidence 70%
  • Typhoid Fever 50%
  • Serotype 40%
  19 Downloads (Pure)

• Methods for the field evaluation of quantitative G6PD diagnostics: A review

  Ley, B., Bancone, G., Von Seidlein, L., Thriemer, K., Richards, J. S., Domingo, G. J. & Price, R. N., 11 Sep 2017, In: Malaria Journal. 16, p. 1-9 9 p., 361.

  Research output: Contribution to journal › Review article › peer-review

  Open Access

  File

  • Glucose 6 Phosphate Dehydrogenase 100%
  • Ensure 16%
  • Plasmodium vivax 16%
  • Enzyme 16%
  • Population Study 16%
  17 Downloads (Pure)

• Molecular analysis demonstrates high prevalence of chloroquine resistance but no evidence of artemisinin resistance in Plasmodium falciparum in the Chittagong Hill Tracts of Bangladesh

  Alam, M. S., Ley, B., Nima, M. K., Johora, F. T., Hossain, M. E., Thriemer, K., Auburn, S., Marfurt, J., Price, R. N. & Khan, W. A., 15 Aug 2017, In: Malaria Journal. 16, p. 1-6 6 p., 335.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Artemisinin 100%
  • Polymerase Chain Reaction 75%
  • Chloroquine 75%
  • Clinical Trial 75%
  • Mutation 75%
  9 Downloads (Pure)

• Population-based incidence, seasonality and serotype distribution of invasive salmonellosis among children in Nanoro, rural Burkina Faso

  Guiraud, I., Post, A., Diallo, S. N., Lompo, P., Maltha, J., Thriemer, K., Tahita, C. M., Ley, B., Derra, K., Bottieau, E., Kazienga, A., Schurmans, C., Ravinetto, R., Rouamba, E., Griensven, J. V., Bertrand, S., Tinto, H. & Jacobs, J., 10 Jul 2017, In: PLoS One. 12, 7, p. 1-17 17 p., e0178577.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Incidence 100%
  • Salmonella 87%
  • Salmonella Enterica Serovar Typhi 75%
  • Child 50%
  • Malaria 37%
  32 Downloads (Pure)
• 2016

  Comparison of three screening test kits for G6PD enzyme deficiency: Implications for its use in the radical cure of vivax malaria in remote and resource-poor areas in the Philippines

  Espino, F., Bibit, JA., Sornillo, JB., Tan, A., von Seidlein, L. & Ley, B., 2016, In: PLoS One. 11, 2, p. 1-12 12 p., e014817.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Venous Blood 100%
  • Glucose 6 Phosphate Dehydrogenase 80%
  • Capillary Blood 80%
  • Male 40%
  • Blood Sampling 40%
  30 Downloads (Pure)

• G6PD deficiency and antimalarial efficacy for uncomplicated malaria in Bangladesh: A prospective observational study

  Ley, B., Alam, MS., Ley-Thriemer, K., Hossain, M., Kibria, MG., Auburn, S., Poirot, E., Price, R. & Khan, W., 2016, In: PLoS One. 11, 4, p. 1-15 15 p., e0154015.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Malaria 100%
  • Antimalarial Agent 74%
  • Hemoglobin 74%
  • Malaria Falciparum 50%
  • Mixed Infection 50%
  17 Downloads (Pure)