Projects per year
Personal profile
Research interests
Deborah Holt is a molecular biologist with a research focus on bacterial and parasitic pathogens of significance in tropical regions of the world, including remote Australian Indigenous communities. She has a particular interest in pathogen genome sequence data analysis and its application in the development of rapid molecular surveillance and identification tools.
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
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SDG 2 Zero Hunger -
SDG 3 Good Health and Well-being -
SDG 5 Gender Equality -
SDG 6 Clean Water and Sanitation -
SDG 16 Peace, Justice and Strong Institutions
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Dive into the research topics where Deborah Holt is active. These topic labels come from the works of this person. Together they form a unique fingerprint.
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Collaborations and top research areas from the last five years
Recent external collaboration on country/territory level. Dive into details by clicking on the dots or
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Comparative genomic analyses of parasitic and free living mites of medical and veterinary importance
Holt, D. (Principal Investigator/Chief Investigator A), Fischer, K. (Co Investigator/Chief Investigator B), Burgess, S. (Chief Investigator C) & Mounsey, K. (Chief Investigator D)
1/01/14 → 31/12/17
Project: Research
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Development of a rapid point-of-care molecular diagnostic for scabies and co-infections
Paxman, M. (Student Investigator) & Holt, D. (Supervisor)
1/07/25 → 30/06/28
Project: Research
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EOI: The effects of mass drug administration on scabies and strongyloidiasis prevalence five years later
Kearns, T. (Principal Investigator/Chief Investigator A), Andrews, R. (Co Investigator/Chief Investigator B), Holt, D. (Chief Investigator C) & Currie, B. (Chief Investigator D)
1/07/15 → 30/06/16
Project: Research
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Forensic approach for reservoir identification for serious S. aureus infections in Top End dialysis clients.
Giffard, P. (Principal Investigator/Chief Investigator A), Holt, D. (Co Investigator/Chief Investigator B), Hughes, J. (Chief Investigator C), Perry, G. (Chief Investigator D), Tong, S. Y. C. (Chief Investigator E) & Harris, T. (Project Manager)
1/01/12 → 31/12/15
Project: Research
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Inside the skin: understanding different host responses in scabies.
Mounsey, K. (Principal Investigator/Chief Investigator A), McCarthy, J. (Co Investigator/Chief Investigator B), Walton, S. F. (Chief Investigator C), Holt, D. (Chief Investigator D) & Currie, B. (Chief Investigator E)
1/01/12 → 31/12/14
Project: Research
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Investigations into the Pathophysiology, Diagnosis, and Treatment Efficacy of Chlamydiosis in Koalas
Holt, D. (Principal Investigator/Chief Investigator A) & Robin Ep Van Aggelen , A. H. C. (Student Investigator)
24/03/25 → …
Project: HDR Project › PhD
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Prevalence of scabies and strongyloidiasis five years after two mass drug administrations in a remote Australian Aboriginal community.
Kearns, T. (Principal Investigator/Chief Investigator A), Andrews, R. (Associate Investigator), Currie, B. (Associate Investigator) & Holt, D. (Associate Investigator)
1/07/15 → 31/12/16
Project: Research
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Invasive Streptococcus dysgalactiae subspecies equisimilis compared with Streptococcus pyogenes in Australia, 2011–23, and the emergence of a multi-continent stG62647 lineage: a retrospective clinical and genomic epidemiology study
Xie, O., Featherstone, L., Nguyen, A. N. T., Hayes, A. J., Pitt, M. E., Spring, S., Liu, A., Tonkin-Hill, G., Dotel, R., Joshi Rai, N., Rofe, A., Duchêne, S., Holt, D. C., Judd, L. M., Coin, L. J. M., Krause, V. L., O'Sullivan, M. V. N., Baird, R. W., Bond, K. & Howden, B. P. & 4 others, , Oct 2025, In: The Lancet Microbe. 6, 10, p. 1-12 12 p., 101182.Research output: Contribution to journal › Article › peer-review
Open AccessFile3 Link opens in a new tab Citations (Scopus)2 Downloads (Pure) -
Temporal and geographical lineage dynamics of invasive Streptococcus pyogenes in Australia from 2011 to 2023: a retrospective, multicentre, clinical and genomic epidemiology study
Xie, O., Chisholm, R. H., Featherstone, L., Nguyen, A. N. T., Hayes, A. J., Jespersen, M. G., Zachreson, C., Tellioglu, N., Tonkin-Hill, G., Dotel, R., Spring, S., Liu, A., Rofe, A., Duchene, S., Sherry, N. L., Baird, R. W., Krause, V. L., Holt, D. C., Coin, L. J. M. & Rai, N. J. & 8 others, , Jun 2025, In: The Lancet Microbe. 6, 6, p. 1-13 13 p., 101053.Research output: Contribution to journal › Article › peer-review
Open AccessFile6 Link opens in a new tab Citations (Scopus)26 Downloads (Pure) -
Overlapping Streptococcus pyogenes and Streptococcus dysgalactiae subspecies equisimilis household transmission and mobile genetic element exchange
Xie, O., Zachreson, C., Tonkin-Hill, G., Price, D. J., Lacey, J. A., Morris, J. M., McDonald, M. I., Bowen, A. C., Giffard, P. M., Currie, B. J., Carapetis, J. R., Holt, D. C., Bentley, S. D., Davies, M. R. & Tong, S. Y. C., Dec 2024, In: Nature Communications. 15, 1, p. 1-12 12 p., 3477.Research output: Contribution to journal › Article › peer-review
Open AccessFile16 Link opens in a new tab Citations (Scopus)161 Downloads (Pure) -
An outbreak of acute rheumatic fever in a remote Aboriginal community
Egoroff, N., Bloomfield, H., Gondarra, W., Yambalpal, B., Guyula, T., Forward, D., Lyons, G., O’Connor, E., Sanderson, L., Dowden, M., Williams, D., De Dassel, J. L., Coffey, P., Dhurrkay, E. R., Gondarra, V., Holt, D., Krause, V. L., Currie, B. J., Griffiths, K. & Dempsey, K. & 1 others, , Oct 2023, In: Australian and New Zealand Journal of Public Health. 47, 5, p. 1-7 7 p., 100077.Research output: Contribution to journal › Article › peer-review
Open AccessFile3 Link opens in a new tab Citations (Scopus)90 Downloads (Pure) -
Australian Society for Parasitology 2023: One Health, One Globe
Holt, D. C., Kho, S., Doerig, C., O'Connor, S. Y., Ray, M., Widdicombe, M., Hall, L. M., Tan, A. F., Ho, T. K. C., Hysa, A., Pekin, K. & Brown, K., Dec 2023, In: Trends in Parasitology. 39, 12, p. 982-988 7 p.Research output: Contribution to journal › Comment/debate › peer-review
Open Access -
Evaluating the role of asymptomatic throat carriage of Streptococcus pyogenes in impetigo transmission in remote Aboriginal communities in Northern Territory, Australia: A retrospective genomic analysis
Lacey, J. A., Marcato, A. J., Chisholm, R. H., Campbell, P. T., Zachreson, C., Price, D. J., James, T. B., Morris, J. M., Gorrie, C. L., McDonald, M. I., Bowen, A. C., Giffard, P. M., Holt, D. C., Currie, B. J., Carapetis, J. R., Andrews, R. M., Davies, M. R., Geard, N., McVernon, J. & Tong, S. Y. C., Jul 2023, In: The Lancet Microbe. 4, 7, p. e524-e533 10 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile21 Link opens in a new tab Citations (Scopus)173 Downloads (Pure) -
minSNPs: An R package for the derivation of resolution-optimised SNP sets from microbial genomic data
Hoon, K. S., Holt, D. C., Auburn, S., Shaw, P. & Giffard, P. M., 2023, In: PEERJ. 11, p. 1-19 e15339.Research output: Contribution to journal › Article › peer-review
Open AccessFile84 Downloads (Pure)
Press/Media
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Data on Streptococcus pyogenes Detailed by Researchers at Charles Darwin University (Staphylococcus aureus and Streptococcus pyogenes in the north: distinctively different)
30/12/22
1 item of Media coverage
Press/Media: Research
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New Life Sciences Findings from Charles Darwin University Described (minSNPs: an R package for the derivation of resolution-optimised SNP sets from microbial genomic data)
Holt, D., Giffard, P. & Auburn, S.
9/06/23
1 item of Media coverage
Press/Media: Research