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  • Jutta Marfurt
2020

Molecular surveillance over 14 years confirms reduction of Plasmodium vivax and falciparum transmission after implementation of Artemisinin-based combination therapy in Papua, Indonesia

Pava, Z., Puspitasari, A. M., Rumaseb, A., Handayuni, I., Trianty, L., Utami, R. A. S., Tirta, Y. K., Burdam, F., Kenangalem, E., Wirjanata, G., Kho, S., Trimarsanto, H., Anstey, N. M., Poespoprodjo, J. R., Noviyanti, R., Price, R. N., Marfurt, J. & Auburn, S., 1 May 2020, In : PLoS Neglected Tropical Diseases. 14, 5, p. 1-16 16 p., e0008295.

Research output: Contribution to journalArticle

Open Access
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2019

3,3′-Disubstituted 5,5′-Bi(1,2,4-triazine) Derivatives with Potent in Vitro and in Vivo Antimalarial Activity

Xue, L., Shi, D. H., Harjani, J. R., Huang, F., Beveridge, J. G., Dingjan, T., Ban, K., Diab, S., Duffy, S., Lucantoni, L., Fletcher, S., Chiu, F. C. K., Blundell, S., Ellis, K., Ralph, S. A., Wirjanata, G., Teguh, S., Noviyanti, R., Chavchich, M., Creek, D. & 10 others, Price, R. N., Marfurt, J., Charman, S. A., Cuellar, M. E., Strasser, J. M., Dahlin, J. L., Walters, M. A., Edstein, M. D., Avery, V. M. & Baell, J. B., 14 Mar 2019, In : Journal of Medicinal Chemistry. 62, 5, p. 2485-2498 14 p.

Research output: Contribution to journalArticle

Analysis of erroneous data entries in paper based and electronic data collection

Ley, B., Rijal, K. R., Marfurt, J., Adhikari, N. R., Banjara, M. R., Shrestha, U. T., Thriemer, K., Price, R. N. & Ghimire, P., 22 Aug 2019, In : BMC Research Notes. 12, 1, p. 1-6 6 p., 537.

Research output: Contribution to journalArticle

Open Access
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Genomic Analysis of Plasmodium vivax in Southern Ethiopia Reveals Selective Pressures in Multiple Parasite Mechanisms

Auburn, S., Getachew, S., Pearson, R. D., Amato, R., Miotto, O., Trimarsanto, H., Zhu, S. J., Rumaseb, A., Marfurt, J., Noviyanti, R., Grigg, M. J., Barber, B., William, T., Goncalves, S. M., Drury, E., Sriprawat, K., Anstey, N. M., Nosten, F., Petros, B., Aseffa, A. & 3 others, McVean, G., Kwiatkowski, D. P. & Price, R. N., 1 Dec 2019, In : Journal of Infectious Diseases. 220, 11, p. 1738-1749 12 p.

Research output: Contribution to journalArticle

Open Access

Malaria morbidity and mortality following introduction of a universal policy of artemisinin-based treatment for malaria in Papua, Indonesia: A longitudinal surveillance study

Kenangalem, E., Poespoprodjo, J. R., Douglas, N. M., Burdam, F. H., Gdeumana, K., Chalfein, F., Prayoga, Thio, F., Devine, A., Marfurt, J., Waramori, G., Yeung, S., Noviyanti, R., Penttinen, P., Bangs, M. J., Sugiarto, P., Simpson, J. A., Soenarto, Y., Anstey, N. M. & Price, R. N., 29 May 2019, In : PLoS Medicine. 16, 5, p. 1-23 23 p., 1002815.

Research output: Contribution to journalArticle

Open Access
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Short-course primaquine for the radical cure of Plasmodium vivax malaria: a multicentre, randomised, placebo-controlled non-inferiority trial

Taylor, W. R. J., Thriemer, K., von Seidlein, L., Yuentrakul, P., Assawariyathipat, T., Assefa, A., Auburn, S., Chand, K., Chau, N. H., Cheah, P. Y., Dong, L. T., Dhorda, M., Degaga, T. S., Devine, A., Ekawati, L. L., Fahmi, F., Hailu, A., Hasanzai, M. A., Hien, T. T., Khu, H. & 25 others, Ley, B., Lubell, Y., Marfurt, J., Mohammad, H., Moore, K. A., Naddim, M. N., Pasaribu, A. P., Pasaribu, S., Promnarate, C., Rahim, A. G., Sirithiranont, P., Solomon, H., Sudoyo, H., Sutanto, I., Thanh, N. V., Tuyet-Trinh, N. T., Waithira, N., Woyessa, A., Yamin, F. Y., Dondorp, A., Simpson, J. A., Baird, J. K., White, N. J., Day, N. P. & Price, R. N., 14 Sep 2019, In : The Lancet. 394, 10202, p. 929-938 10 p.

Research output: Contribution to journalArticle

Open Access
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2018

Erratum for Brunschwig et al., "UCT943, a Next-Generation Plasmodium falciparum PI4K Inhibitor Preclinical Candidate for the Treatment of Malaria": Antimicrob Agents Chemother

Brunschwig, C., Lawrence, N., Taylor, D., Abay, E., Njoroge, M., Basarab, G. S., Le Manach, C., Paquet, T., Gonzalez Cabrera, D., Nchinda, A. T., de Kock, C., Wiesner, L., Denti, P., Waterson, D., Blasco, B., Leroy, D., Witty, M. J., Donini, C., Duffy, J., Wittlin, S. & 28 others, White, K. L., Charman, S. A., Jimenez-Diaz, M. B., Angulo-Barturen, I., Herreros, E., Gamo, F. J., Rochford, R., Mancama, D., Coetzer, T. L., van der Watt, M. E., Reader, J., Birkholtz, L. M., Marsh, K. C., Solapure, S. M., Burke, J. E., McPhail, J. A., Vanaerschot, M., Fidock, D. A., Fish, P. V., Siegl, P., Smith, D. A., Wirjanata, G., Noviyanti, R., Price, R. N., Marfurt, J., Silue, K. D., Street, L. J. & Chibale, K., 27 Nov 2018, In : Antimicrobial Agents and Chemotherapy. 62, 11, p. 1-2 2 p.

Research output: Contribution to journalComment/debate

Open Access

Genomic analysis of a pre-elimination Malaysian Plasmodium vivax population reveals selective pressures and changing transmission dynamics

Auburn, S., Benavente, E. D., Miotto, O., Pearson, R. D., Amato, R., Grigg, M. J., Barber, B. E., William, T., Handayuni, I., Marfurt, J., Trimarsanto, H., Noviyanti, R., Sriprawat, K., Nosten, F., Campino, S., Clark, T. G., Anstey, N. M., Kwiatkowski, D. P. & Price, R. N., 3 Jul 2018, In : Nature Communications. 9, 1, p. 1-12 12 p., 2585.

Research output: Contribution to journalArticle

Open Access
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Laboratory challenges of Plasmodium species identification in Aceh Province, Indonesia, a malaria elimination setting with newly discovered P. knowlesi

Coutrier, F. N., Tirta, Y. K., Cotter, C., Zarlinda, I., González, I. J., Schwartz, A., Maneh, C., Marfurt, J., Murphy, M., Herdiana, H., Anstey, N. M., Greenhouse, B., Hsiang, M. S. & Noviyanti, R., 30 Nov 2018, In : PLoS Neglected Tropical Diseases. 12, 11, p. 1-11 11 p., e0006924.

Research output: Contribution to journalArticle

Open Access
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Low risk of recurrence following artesunate-Sulphadoxine-pyrimethamine plus primaquine for uncomplicated Plasmodium falciparum and Plasmodium vivax infections in the Republic of the Sudan

Hamid, M. M. A., Thriemer, K., Elobied, M. E., Mahgoub, N. S., Boshara, S. A., Elsafi, H. M. H., Gumaa, S. A., Hamid, T., Abdelbagi, H., Basheir, H. M., Marfurt, J., Chen, I., Gosling, R., Price, R. N. & Ley, B., 16 Mar 2018, In : Malaria Journal. 17, 1, p. 1-14 14 p., 117.

Research output: Contribution to journalArticle

Open Access
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Plasmodium falciparum artemisinin resistance monitoring in Sabah, Malaysia: In vivo therapeutic efficacy and kelch13 molecular marker surveillance

Grigg, M. J., William, T., Piera, K. A., Rajahram, G. S., Jelip, J., Aziz, A., Menon, J., Marfurt, J., Price, R. N., Auburn, S., Barber, B. E., Yeo, T. W. & Anstey, N. M., 10 Dec 2018, In : Malaria Journal. 17, 1, p. 1-8 8 p., 463.

Research output: Contribution to journalArticle

Open Access
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Quantifying primaquine effectiveness and improving adherence: A round table discussion of the APMEN Vivax Working Group

Thriemer, K., Bobogare, A., Ley, B., Gudo, C. S., Alam, M. S., Anstey, N. M., Ashley, E., Baird, J. K., Gryseels, C., Jambert, E., Lacerda, M., Laihad, F., Marfurt, J., Pasaribu, A. P., Poespoprodjo, J. R., Sutanto, I., Taylor, W. R., Van Den Boogaard, C., Battle, K. E., Dysoley, L. & 78 others, Ghimire, P., Hawley, B., Hwang, J., Khan, W. A., Mudin, R. N. B., Sumiwi, M. E., Ahmed, R., Aktaruzzaman, M. M., Awasthi, K. R., Bardaji, A., Bell, D., Boaz, L., Burdam, F. H., Chandramohan, D., Cheng, Q., Chindawongsa, K., Culpepper, J., Das, S., Deray, R., Desai, M., Domingo, G., Duoquan, W., Duparc, S., Floranita, R., Gerth-Guyette, E., Howes, R. E., Hugo, C., Jagoe, G., Sariwati, E., Jhora, S. T., Jinwei, W., Karunajeewa, H., Kenangalem, E., Lal, B. K., Landuwulang, C., Le Perru, E., Lee, S. E., Makita, L. S., McCarthy, J., Mekuria, A., Mishra, N., Naket, E., Nambanya, S., Nausien, J., Duc, T. N., Thi, T. N., Noviyanti, R., Pfeffer, D., Qi, G., Rahmalia, A., Rogerson, S., Samad, I., Sattabongkot, J., Satyagraha, A., Shanks, D., Sharma, S. N., Sibley, C. H., Sungkar, A., Syafruddin, D., Talukdar, A., Tarning, J., Ter Kuile, F., Thapa, S., Theodora, M., Huy, T. T., Waramin, E., Waramori, G., Woyessa, A., Wongsrichanalai, C., Xa, N. X., Yeom, J. S., Hermawan, L., Devine, A., Nowak, S., Jaya, I., Supargiyono, S., Grietens, K. P. & Price, R. N., 20 Jun 2018, In : Malaria Journal. 17, p. 1-7 7 p., 241.

Research output: Contribution to journalMeeting Abstract

Open Access
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The Plasmodium falciparum transcriptome in severe malaria reveals altered expression of genes involved in important processes including surface antigen–encoding var genes

Tonkin-Hill, G. Q., Trianty, L., Noviyanti, R., Nguyen, H. H. T., Sebayang, B. F., Lampah, D. A., Marfurt, J., Cobbold, S. A., Rambhatla, J. S., McConville, M. J., Rogerson, S. J., Brown, G. V., Day, K. P., Price, R. N., Anstey, N. M., Papenfuss, A. T. & Duffy, M. F., 12 Mar 2018, In : PLoS Biology. 16, 3, p. 1-40 40 p., e2004328.

Research output: Contribution to journalArticle

Open Access
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Therapeutic response to dihydroartemisinin-piperaquine for P. falciparum and P. Vivax nine years after its introduction in southern Papua, Indonesia

Poespoprodjo, J. R., Kenangalem, E., Wafom, J., Chandrawati, F., Puspitasari, A. M., Ley, B., Trianty, L., Korten, Z., Surya, A. S., Syafruddin, D., Anstey, N., Marfurt, J., Noviyanti, R. & Price, R., Mar 2018, In : American Journal of Tropical Medicine and Hygiene. 98, 3, p. 677-682 6 p.

Research output: Contribution to journalArticle

Open Access
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Uct943, a next-generation plasmodium falciparum pi4k inhibitor preclinical candidate for the treatment of malaria

Brunschwig, C., Lawrence, N., Taylor, D., Abay, E., Njoroge, M., Basarab, G. S., Le Manach, C., Paquet, T., Cabrera, D. G., Nchinda, A. T., De Kock, C., Wiesner, L., Denti, P., Waterson, D., Blasco, B., Leroy, D., Witty, M. J., Donini, C., Duffy, J., Wittlin, S. & 28 others, White, K. L., Charman, S. A., Jimenez-Diaz, M. B., Angulo-Barturen, I., Herreros, E., Gamo, F. J., Rochford, R., Mancama, D., Coetzer, T. L., Van der Watt, M. E., Reader, J., Birkholtz, L. M., Marsh, K. C., Solapure, S. M., Burke, J. E., McPhail, J. A., Vanaerschot, M., Fidock, D. A., Fish, P. V., Siegl, P., Smith, D. A., Wirjanata, G., Noviyanti, R., Price, R. N., Marfurt, J., Silue, K. D., Street, L. J. & Chibaleb, K., 1 Sep 2018, In : Antimicrobial Agents and Chemotherapy. 62, 9, p. 1-16 16 p., e00012-18.

Research output: Contribution to journalArticle

Open Access
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2017

A tetraoxane-based antimalarial drug candidate that overcomes PfK13-C580Y dependent artemisinin resistance

O'Neill, P. M., Amewu, R. K., Charman, S. A., Sabbani, S., Gnädig, N. F., Straimer, J., Fidock, D. A., Shore, E. R., Roberts, N. L., Wong, M. H. L., Hong, W. D., Pidathala, C., Riley, C., Murphy, B., Aljayyoussi, G., Gamo–Benito, F. J., Sanz, L. M., Rodrigues, J., Cortes, C. G., Herreros, E. & 28 others, Angulo-Barturén, I., Jiménez-Díaz, M. B., Bazaga, S. F., Martínez-Martínez, M. S., Campo, B., Sharma, R., Ryan, E., Shackleford, D. M., Campbell, S., Smith, D. A., Wirjanata, G., Noviyanti, R., Price, R. N., Marfurt, J., Palmer, M. J., Copple, I. M., Mercer, A. E., Ruecker, A., Delves, M. J., Sinden, R. E., Siegl, P., Davies, J., Rochford, R., Kocken, C. H. M., Zeeman, A-M., Nixon, G. L., Biagini, G. A. & Ward, S. A., 24 May 2017, In : Nature Communications. 8, p. 1-12 12 p., 15159.

Research output: Contribution to journalArticle

Open Access
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Challenges for achieving safe and effective radical cure of Plasmodium vivax: a round table discussion of the APMEN Vivax Working Group

Thriemer, K., Ley, B., Bobogare, A. B., Dysoley, L., Alam, M. S., Pasaribu, A. P., Sattabongkot-Prachumsri, J. S. P., Jambert, E., Domingo, G. J., Commons, R., Auburn, S., Marfurt, J., Devine, A., Aktaruzzaman, M. M., Sohel, N., Namgay, R. N., Drukpa, T., Sharma, S. N., Sarawati, E., Samad, I. & 47 others, Theodora, M., Nambanya, S., Ounekham, S., Mudin, R. N. B., Da Thakur, G., Makita, L. S., Deray, R., Lee, S. E., Boaz, L., Danansuriya, M. N., Mudiyanselage, S. D., Chinanonwait, N., Kitchakarn, S., Nausien, J., Naket, E., Duc, T. N., Do Manh, H., Hong, Y. S., Cheng, Q., Richards, J. S., Kusriastuti, R., Satyagraha, A. W., Noviyanti, R., Ding, X. C., Khan, W. A., Swe Phru, C., Guoding, Z., Qi, G., Kaneko, A., Miotto, O., Nguitragool, W., Roobsoong, W., Battle, K., Howes, R. E., Roca-Feltrer, A., Duparc, S., Bhowmick, I. P., Kenangalem, E., Bibit, J. A., Barry, A. E., Sintasath, D., Abeyasinghe, R., Sibley, C. H., McCarthy, J., Von Seidlein, L., Baird, J. K. & Price, R. N., 5 Apr 2017, In : Malaria Journal. 16, 141, p. 1-9 9 p., 141.

Research output: Contribution to journalMeeting Abstract

Open Access
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Genetic micro-epidemiology of malaria in Papua Indonesia: Extensive P. vivax diversity and a distinct subpopulation of asymptomatic P. falciparum infections

Pava, Z., Noviyanti, R., Handayuni, I., Trimarsanto, H., Trianty, L., Burdam, F. H., Kenangalem, E., Utami, R. A. S., Tirta, Y. K., Coutrier, F., Poespoprodjo, J. R., Price, R. N., Marfurt, J. & Auburn, S., 1 May 2017, In : PLoS One. 12, 5, p. 1-13 13 p., e0177445.

Research output: Contribution to journalArticle

Open Access
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Genomic characterization of recrudescent plasmodium malariae after treatment with artemether/lumefantrine

Rutledge, G. G., Marr, I., Huang, G. K. L., Auburn, S., Marfurt, J., Sanders, M., White, N. J., Berriman, M., Newbold, C. I., Anstey, N. M., Otto, T. D. & Price, R. N., 1 Aug 2017, In : Emerging Infectious Diseases. 23, 8, p. 1300-1307 8 p.

Research output: Contribution to journalReview article

Open Access
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Molecular analysis demonstrates high prevalence of chloroquine resistance but no evidence of artemisinin resistance in Plasmodium falciparum in the Chittagong Hill Tracts of Bangladesh

Alam, M. S., Ley, B., Nima, M. K., Johora, F. T., Hossain, M. E., Thriemer, K., Auburn, S., Marfurt, J., Price, R. N. & Khan, W. A., 15 Aug 2017, In : Malaria Journal. 16, p. 1-6 6 p., 335.

Research output: Contribution to journalArticle

Open Access
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Passively versus actively detected malaria: Similar genetic diversity but different complexity of infection

Pava, Z., Handayuni, I., Trianty, L., Utami, R. A. S., Tirta, Y. K., Puspitasari, A. M., Burdam, F., Kenangalem, E., Wirjanata, G., Kho, S., Trimarsanto, H., Anstey, N., Poespoprodjo, J. R., Noviyanti, R., Price, R. N., Marfurt, J. & Auburn, S., Dec 2017, In : American Journal of Tropical Medicine and Hygiene. 97, 6, p. 1788-1796 9 p.

Research output: Contribution to journalArticle

Open Access
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Plasmodium falciparum and Plasmodium vivax demonstrate contrasting chloroquine resistance reversal phenotypes

Wirjanata, G., Handayuni, I., Prayoga, P., Leonardo, L., Apriyanti, D., Trianty, L., Wandosa, R., Gobay, B., Kenangalem, E., Poespoprodjo, J. R., Noviyanti, R., Kyle, D. E., Cheng, Q., Price, R. N. & Marfurt, J., 25 Jul 2017, In : Antimicrobial Agents and Chemotherapy. 61, 8, p. 1-10 10 p., e00355.

Research output: Contribution to journalArticle

Open Access
2016

Analysis of ex vivo drug response data of Plasmodium clinical isolates: The pros and cons of diferent computer programs and online platforms

Wirjanata, G., Handayuni, I., Zaloumis, S., Chalfein, F., Prayoga, P., Kenangalem, E., Poespoprodjo, J. R., Noviyanti, R., Simpson, J., Price, R. & Marfurt, J., 2016, In : Malaria Journal. 15, 1, p. 1-10 10 p., 137.

Research output: Contribution to journalArticle

Open Access
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Asymptomatic Vivax and Falciparum Parasitaemia with Helminth Co-Infection: Major Risk Factors for Anaemia in Early Life

Burdam, F. H., Hakimi, M., Thio, F., Kenangalem, E., Indrawanti, R., Noviyanti, R., Trianty, L., Marfurt, J., Handayuni, I., Seonarto, Y., DOUGLAS, N. N., Anstey, N., Price, R. & Poespoprodjo, J., 2016, In : PLoS One. 11, 8 , p. 1-15 15 p., e0160917.

Research output: Contribution to journalArticle

Open Access
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A Triazolopyrimidine-Based Dihydroorotate Dehydrogenase Inhibitor with Improved Drug-like Properties for Treatment and Prevention of Malaria

Phillips, M. A., White, K. L., Kokkonda, S., Deng, X., White, J., El Mazouni, F., Marsh, K., Tomchick, D. R., Manjalanagara, K., Rudra, K. R., Wirjanata, G., Noviyanti, R., Price, R. N., Marfurt, J., Shackleford, D. M., Chiu, F. C. K., Campbell, M., Jimenez-Diaz, M. B., Bazaga, S. F., Angulo-Barturen, I. & 16 others, Martinez, M. S., Lafuente-Monasterio, M., Kaminsky, W., Silue, K., Zeeman, A. M., Kocken, C., Leroy, D., Blasco, B., Rossignol, E., Rueckle, T., Matthews, D., Burrows, J. N., Waterson, D., Palmer, M. J., Rathod, P. K. & Charman, S. A., 9 Dec 2016, In : ACS Infectious Diseases. 2, 12, p. 945-957 13 p.

Research output: Contribution to journalArticle

Characterization of blood dendritic and regulatory T cells in asymptomatic adults with sub-microscopic Plasmodium falciparum or Plasmodium vivax infection

Kho, S., Marfurt, J., Handayuni, I., Pava, Z., Noviyanti, R., Kusuma, A., Piera, K., Burdam, F. H., Kenangalem, E., Lampah, D., Engwerda, C., Poespoprodjo, J. R., Price, R., Anstey, N., Minigo, G. & Woodberry, T., 2016, In : Malaria Journal. 15, 1, p. 1-9 9 p., 328.

Research output: Contribution to journalArticle

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Characterization of Novel Antimalarial Compound ACT-451840: Preclinical Assessment of Activity and Dose–Efficacy Modeling

Le Bihan, A., de Kanter, R., Angulo-Barturen, I., Binkert, C., Boss, C., Brun, R., Brunner, R., Buchmann, S., Burrows, J., Dechering, K. J., Delves, M., Ewerling, S., Ferrer, S., Fischli, C., Gamo–Benito, F. J., Gnädig, N. F., Heidmann, B., Jiménez-Díaz, M. B., Leroy, D., Martínez, M. S. & 20 others, Meyer, S., Moehrle, J. J., Ng, C. L., Noviyanti, R., Ruecker, A., Sanz, L. M., Sauerwein, R. W., Scheurer, C., Schleiferboeck, S., Sinden, R., Snyder, C., Straimer, J., Wirjanata, G., Marfurt, J., Price, R. N., Weller, T., Fischli, W., Fidock, D. A., Clozel, M. & Wittlin, S., 1 Oct 2016, In : PLoS Medicine. 13, 10, e1002138.

Research output: Contribution to journalArticle

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Differences in PfEMP1s recognized by antibodies from patients with uncomplicated or severe malaria

Duffy, M., Noviyanti, R., Tsuboi, T., Feng, ZP., Trianty, L., Sebayang, B., Takashima, E., Sumardy, F., Lampah, D., Turner, L., Lavstsen, T., Fowkes, F. J. I., Siba, P., Rogerson, S., Theander, T., Marfurt, J., Price, R., Anstey, N., Brown, G. & Papenfuss, AT., 2016, In : Malaria Journal. 15, 1, p. 1-12 12 p., 258.

Research output: Contribution to journalArticle

Open Access
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Dihydrofolate-reductase mutations in plasmodium knowlesi appear unrelated to selective drug pressure from putative human-to-human transmission in Sabah, Malaysia

Grigg, M., Barber, B., Marfurt, J., Imwong, M., William, T., Bird, E., Piera, K., Aziz, A., Boonyuen, U., Drakeley, C., Cox, J., White, N. J., Cheng, Q., Yeo, T., Auburn, S. & Anstey, N., 2016, In : PLoS One. 11, 3, p. 1-19 19 p., e0149519.

Research output: Contribution to journalArticle

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Expression of Plasmodium vivax crt-o is related to parasite stage but not ex vivo chloroquine susceptibility

Pava, Z., Handayuni, I., Wirjanata, G., To, S., Trianty, L., Noviyanti, R., Poespoprodjo, J. R., Auburn, S., Price, R. & Marfurt, J., Jan 2016, In : Antimicrobial Agents and Chemotherapy. 60, 1, p. 361-367 7 p.

Research output: Contribution to journalArticle

Open Access

Genomic analysis of local variation and recent evolution in Plasmodium vivax

Pearson, R. D., Amato, R., Auburn, S., Miotto, O., Almagro-Garcia, J., Amaratunga, C., Suon, S., Mao, S., Noviyanti, R., Trimarsanto, H., Marfurt, J., Anstey, N. M., WILLIAM, T., Boni, M. F., Dolecek, C., Tran, H. T., White, N. J., Michon, P., Siba, P., Tavul, L. & 24 others, Harrison, G., Barry, A. E., Mueller, I., Ferreira, M. U., Karunaweera, N., Randrianarivelojosia, M., Gao, Q., Hubbart, C., Hart, L., Jeffery, B., Drury, E., Mead, D., Kekre, M., Campino, S., Manske, M., Cornelius, V. J., MacInnis, B., Rockett, K. A., Miles, A., Rayner, J. C., Fairhurst, R. M., Nosten, F., Price, R. N. & Kwiatkowski, D. P., 1 Aug 2016, In : Nature Genetics. 48, 8, p. 959-964 6 p.

Research output: Contribution to journalArticle

Genomic epidemiology of artemisinin resistant malaria

Amato, R., Miotto, O., Woodrow, C. J., Almagro-Garcia, J., Sinha, I., Campino, S., Mead, D., Drury, E., Kekre, M., Sanders, M., Amambua-Ngwa, A., Amaratunga, C., Amenga-Etego, L., Andrianaranjaka, V., Apinjoh, T., Ashley, E., Auburn, S., Awandare, G. A., Baraka, V., Barry, A. & 77 others, Boni, M. F., Borrmann, S., Bousema, T., Branch, O., Bull, P. C., Chotivanich, K., Conway, D. J., Craig, A., Day, N. P., Djimdé, A., Dolecek, C., Dondorp, A. M., Drakeley, C., Duffy, P., Echeverry, D. F., Egwang, T. G., Fairhurst, R. M., Faiz, A., Fanello, C. I., Hien, T. T., Hodgson, A., Imwong, M., Ishengoma, D., Lim, P., Lon, C., Marfurt, J., Marsh, K., Mayxay, M., Michon, P., Mobegi, V., Mokuolu, O. A., Montgomery, J., Mueller, I., Kyaw, M. P., Newton, P. N., Nosten, F., Noviyanti, R., Nzila, A., Ocholla, H., Oduro, A., Onyamboko, M., Ouedraogo, J. B., Phyo, A. P. P., Plowe, C., Price, R. N., Pukrittayakamee, S., Randrianarivelojosia, M., Ringwald, P., Ruiz, L., Saunders, D., Shayo, A., Siba, P., Takala-Harrison, S., Thanh, T. N. N., Thathy, V., Verra, F., Wendler, J., White, N. J., Ye, H., Cornelius, V. J., Giacomantonio, R., Muddyman, D., Henrichs, C., Malangone, C., Jyothi, D., Pearson, R. D., Rayner, J. C., McVean, G., Rockett, K. A., Miles, A., Vauterin, P., Jeffery, B., Manske, M., Stalker, J., Macinnis, B., Kwiatkowski, D. P. & MalariaGEN Plasmodium falciparum Community Project, 4 Mar 2016, In : eLife. 5, MARCH2016, p. 1-29 29 p., e08714.

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Submicroscopic and asymptomatic plasmodium parasitaemia associated with significant risk of anaemia in Papua, Indonesia

Pava, Z., Burdam, F. H., Handayuni, I., Trianty, L., Utami, R. A. S., Tirta, Y. K., Kenangalem, E., Lampah, D., Kusuma, A., Wirjanata, G., Kho, S., Simpson, J. A., Auburn, S., Douglas, N. M., Noviyanti, R., Anstey, N. M., Poespoprodjo, J. R., Marfurt, J. & Price, R. N., 1 Oct 2016, In : PLoS One. 11, 10, e0165340.

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Transfusion-transmitted severe Plasmodium knowlesi malaria in a splenectomized patient with beta-thalassaemia major in Sabah, Malaysia: A case report

Bird, E., Parameswaran, U., Williams, T., Khoo, T., Grigg, M., Aziz, A., Marfurt, J., Yeo, T., Auburn, S., Anstey, N. & Barber, B., 2016, In : Malaria Journal. 15, 1, p. 1-6 6 p., 357.

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2015

A novel multiple-stage antimalarial agent that inhibits protein synthesis

Baragaña, B., Hallyburton, I., Lee, M. C. S., Norcross, N. R., Grimaldi, R., Otto, T. D., Proto, W. R., Blagborough, A. M., Meister, S., Wirjanata, G., Ruecker, A., Upton, L. M., Abraham, T. S., Almeida, M. J., Pradhan, A., Porzelle, A., Martínez, M. S., Bolscher, J. M., Woodland, A., Norval, S. & 43 others, Zuccotto, F., Thomas, J., Simeons, F., Stojanovski, L., Osuna-Cabello, M., Brock, P. M., Churcher, T. S., Sala, K. A., Zakutansky, S. E., Jiménez-Díaz, M. B., Sanz, L. M., Riley, J., Basak, R., Campbell, M., Avery, V. M., Sauerwein, R. W., Dechering, K. J., Noviyanti, R., Campo, B., Frearson, J. A., Angulo-Barturen, I., Ferrer-Bazaga, S., Gamo, F. J., Wyatt, P. G., Leroy, D., Siegl, P., Delves, M. J., Kyle, D. E., Wittlin, S., Marfurt, J., Price, R. N., Sinden, R. E., Winzeler, E. A., Charman, S. A., Bebrevska, L., Gray, D. W., Campbell, S., Fairlamb, A. H., Willis, P. A., Rayner, J. C., Fidock, D. A., Read, K. D. & Gilbert, I. H., 2015, In : Nature. 22, 7556, p. 315-320 6 p.

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Contrasting Ex Vivo efficacies of "Reversed Chloroquine" compounds in chloroquine-resistant Plasmodium falciparum and P. vivax isolates

Wirjanata, G., Sebayang, B., Chalfein, F., Prayoga, P., Handayuni, I., Noviyanti, R., Kenangalem, E., Poespoprodjo, J. R., Burgess, S., Peyton, D. H., Price, R. & Marfurt, J., Sep 2015, In : Antimicrobial Agents and Chemotherapy. 59, 9, p. 5721-5726 6 p.

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Open Access

Contrasting Transmission Dynamics of Co-endemic Plasmodium vivax and P. falciparum: Implications for Malaria Control and Elimination

Noviyanti, R., Farah, C., Utami, R. A. S., Trimarsanto, H., Tirta, Y. K., Trianty, L., Kusuma, A., Sutanto, A., Kosasih, A., Kusriastuti, Hawley, W. A., Laihad, F., Lobo, N., Marfurt, J., Clark, T., Price, R. & Auburn, S., 2015, In : PLoS Neglected Tropical Diseases. 9, 5 1, p. 1-19 19 p., e0003739.

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Potent Ex Vivo activity of naphthoquine and methylene blue against drug-resistant clinical isolates of Plasmodium falciparum and Plasmodium vivax

Wirjanata, G., Sebayang, B., Chalfein, F., Prayoga, P., Handayuni, I., Trianty, L., Kenangalem, E., Noviyanti, R., Campo, B., Poespoprodjo, J. R., Möhrle, J., Price, R. & Marfurt, J., Oct 2015, In : Antimicrobial Agents and Chemotherapy. 59, 10, p. 6117-6124 8 p.

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Preserved dendritic cell HLA-DR expression and reduced regulatory T cell activation in Asymptomatic Plasmodium falciparum and P. vivax infection

Kho, S., Marfurt, J., Noviyanti, R., Kusuma, A., Piera, K., Burdam, F. H., Kenangalem, E., Lampah, D., Engwerda, C., Poespoprodjo, J. R., Price, R., Anstey, N., Minigo, G. & Woodberry, T., Aug 2015, In : Infection and Immunity. 83, 8, p. 3224-3232 9 p.

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Quantification of Plasmodium ex vivo drug susceptibility by flow cytometry

Wirjanata, G., Handayuni, I., Prayoga, Apriyanti, D., Chalfein, F., Sebayang, B., Kho, S., Noviyanti, R., Kenangalem, E., Campo, B., Poespoprodjo, J. R., Price, R. & Marfurt, J., 2015, In : Malaria Journal. 14, 417, p. 1-10 10 p., 417.

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2014

KAF156 is an antimalarial clinical candidate with potential for use in prophylaxis, treatment, and prevention of disease transmission

Kuhen, K. L., Chatterjee, A. K., Rottmann, M., Gagaring, K., Borboa, R., Buenviaje, J., Chen, Z., Francek, C., Wu, T., Nagle, A., Barnes, S. W., Plouffe, D., Lee, M. C. S., Fidock, D. A., Graumans, W., Van De Vegte-Bolmer, M., Van Gemert, G. J., Wirjanata, G., Sebayang, B., Marfurt, J. & 18 others, Russell, B., Suwanarusk, R., Price, R. N., Nosten, F., Tungtaeng, A., Gettayacamin, M., Sattabongkot, J., Taylor, J., Walker, J. R., Tully, D., Patra, K. P., Flannery, E. L., Vinetz, J. M., Renia, L., Sauerwein, R. W., Winzeler, E. A., Glynne, R. J. & Diagana, T. T., 2014, In : Antimicrobial Agents and Chemotherapy. 58, 9, p. 5060-5067 8 p.

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Pyrazoleamide compounds are potent antimalarials that target Na+ homeostasis in intraerythrocytic Plasmodium falciparum

Vaidya, A. B., Morrisey, J. M., Zhang, Z., Das, S., Daly, T. M., Otto, T. D., Spillman, N. J., Wyvratt, M., Siegl, P., Marfurt, J., Wirjanata, G., Sebayang, B. F., Price, R. N., Chatterjee, A., Nagle, A., Stasiak, M., Charman, S. A., Angulo-Barturen, I., Ferrer, S., Belén Jiménez-Díaz, M. & 11 others, Martínez, M. S., Gamo, F. J., Avery, V. M., Ruecker, A., Delves, M., Kirk, K., Berriman, M., Kortagere, S., Burrows, J., Fan, E. & Bergman, L. W., 2014, In : Nature Communications. 5, p. 1-10 10 p., 5521.

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2013
Open Access

Effective Preparation of Plasmodium vivax Field Isolates for High-Throughput Whole Genome Sequencing

Auburn, S., Marfurt, J., Maslen, G., Campino, S., Ruano-Rubio, V., Manske, M., Machunter, B., Kenangalem, E., Noviyanti, R., Trianty, L., Sebayang, B., Wirjanata, G., Sriprakash, K., Alcock, D., MacInnes, B., Miotto, O., Clark, T., Russell, B., Anstey, N., Nosten, F. & 2 others, Kwiatkowski, D. & Price, R., 2013, In : PLoS One. 8, 1, p. 1-11 11 p., e53160.

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Quinolone-3-diarylethers: A new class of antimalarial drug

Nilsen, A., LaCrue, A. N., White, K. L., Forquer, I. P., Cross, R. M., Marfurt, J., Mather, M. W., Delves, M. J., Shackleford, D. M., Saenz, F. E., Morrisey, J. M., Steuten, J., Mutka, T., Li, Y., Wirjanata, G., Ryan, E., Duffy, S., Kelly, J. X., Sebayang, B. F., Zeeman, A-M. & 21 others, Noviyanti, R., Sinden, R. E., Kocken, C. H. M., Price, R. N., Avery, V. M., Angulo-Barturen, I., Jiménez-Díaz, M. B., Ferrer, S., Herreros, E., Sanz, L. M., Gamo–Benito, F. J., bathurst, I., Burrows, J. N., Siegl, P., Guy, R. K., Winter, R. W., Vaidya, A. B., Charman, S. A., Kyle, D. E., Manetsch, R. & Riscoe, M. K., 20 Mar 2013, In : Science Translational Medicine. 5, 177, p. 1-13 13 p., 177ra37.

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2012

An Analytical Method for Assessing Stage-Specific Drug Activity in Plasmodium vivax Malaria: Implications for Ex Vivo Drug Susceptibility Testing

Kerlin, D., Boyce, K., Marfurt, J., SIMPSON, J., Kenangalem, E., Cheng, Q., Price, R. & Gatton, M., 2012, In : PLoS Neglected Tropical Diseases. 6, 8, e1772.

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Comparative Ex Vivo Activity of Novel Endoperoxides in Multidrug-Resistant Plasmodium falciparum and P. vivax

Marfurt, J., Chalfein, F., Prayoga, P., Wabiser, Wirjanata, G., Sebayang, B., Piera, K., Wittlin, S., Haynes, R., Mohrle, J., Anstey, N., Kenangalem, E. & Price, R., 2012, In : Antimicrobial Agents and Chemotherapy. 56, 10, p. 5258-5263 6 p.

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Phenotypic and genotypic characterisation of drug-resistant Plasmodium vivax

Price, R., Auburn, S., Marfurt, J. & Cheng, Q., 2012, In : Trends in Parasitology. 28, 11, p. 522-529 8 p.

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2011

Ex vivo activity of histone deacetylase inhibitors against multidrug-resistant clinical isolates of Plasmodium falciparum and P. vivax

Marfurt, J., Chalfein, F., Prayoga, P., Wabiser, F., Kenangalem, E., Piera, K., Fairlie, D., Tjitra, E., Anstey, N., Andrews, K. & Price, R., 2011, In : Antimicrobial Agents and Chemotherapy. 55, 3, p. 961-966 6 p.

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Ex Vivo Drug Susceptibility of Ferroquine against Chloroquine-Resistant Isolates of Plasmodium falciparum and P. vivax

Marfurt, J., Chalfein, F., Prayoga, P., Wabiser, F., Kenangalem, E., Piera, K., Machunter, B., Tjitra, E., Anstey, N. & Price, R., 2011, In : Antimicrobial Agents and Chemotherapy. 55, 9, p. 4461-4464 4 p.

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