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2019

Genomic Analysis of Plasmodium vivax in Southern Ethiopia Reveals Selective Pressures in Multiple Parasite Mechanisms

Auburn, S., Getachew, S., Pearson, R. D., Amato, R., Miotto, O., Trimarsanto, H., Zhu, S. J., Rumaseb, A., Marfurt, J., Noviyanti, R., Grigg, M. J., Barber, B., William, T., Goncalves, S. M., Drury, E., Sriprawat, K., Anstey, N. M., Nosten, F., Petros, B., Aseffa, A. & 3 others, McVean, G., Kwiatkowski, D. P. & Price, R. N., 1 Dec 2019, In : Journal of Infectious Diseases. 220, 11, p. 1738-1749 12 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
Plasmodium vivax
Ethiopia
Parasites
Chloroquine
Immune Evasion

Short-course primaquine for the radical cure of Plasmodium vivax malaria: a multicentre, randomised, placebo-controlled non-inferiority trial

Taylor, W. R. J., Thriemer, K., von Seidlein, L., Yuentrakul, P., Assawariyathipat, T., Assefa, A., Auburn, S., Chand, K., Chau, N. H., Cheah, P. Y., Dong, L. T., Dhorda, M., Degaga, T. S., Devine, A., Ekawati, L. L., Fahmi, F., Hailu, A., Hasanzai, M. A., Hien, T. T., Khu, H. & 25 others, Ley, B., Lubell, Y., Marfurt, J., Mohammad, H., Moore, K. A., Naddim, M. N., Pasaribu, A. P., Pasaribu, S., Promnarate, C., Rahim, A. G., Sirithiranont, P., Solomon, H., Sudoyo, H., Sutanto, I., Thanh, N. V., Tuyet-Trinh, N. T., Waithira, N., Woyessa, A., Yamin, F. Y., Dondorp, A., Simpson, J. A., Baird, J. K., White, N. J., Day, N. P. & Price, R. N., 14 Sep 2019, In : The Lancet. 394, 10202, p. 929-938 10 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
File
Primaquine
Vivax Malaria
Placebos
Recurrence
Glucosephosphate Dehydrogenase
7 Downloads (Pure)

Whole genome sequencing of amplified Plasmodium knowlesi DNA from unprocessed blood reveals genetic exchange events between Malaysian Peninsular and Borneo subpopulations

Benavente, E. D., Gomes, A. R., De Silva, J. R., Grigg, M., Walker, H., Barber, B. E., William, T., Yeo, T. W., de Sessions, P. F., Ramaprasad, A., Ibrahim, A., Charleston, J., Hibberd, M. L., Pain, A., Moon, R. W., Auburn, S., Ling, L. Y., Anstey, N. M., Clark, T. G. & Campino, S., 1 Dec 2019, In : Scientific Reports. 9, 1, p. 1-11 11 p., 9873.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
File
Borneo
Plasmodium knowlesi
Genome
Malaysia
Parasites
2018
12 Downloads (Pure)

Genomic analysis of a pre-elimination Malaysian Plasmodium vivax population reveals selective pressures and changing transmission dynamics

Auburn, S., Benavente, E. D., Miotto, O., Pearson, R. D., Amato, R., Grigg, M. J., Barber, B. E., William, T., Handayuni, I., Marfurt, J., Trimarsanto, H., Noviyanti, R., Sriprawat, K., Nosten, F., Campino, S., Clark, T. G., Anstey, N. M., Kwiatkowski, D. P. & Price, R. N., 3 Jul 2018, In : Nature Communications. 9, 1, p. 1-12 12 p., 2585.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
File
Plasmodium vivax
Malaysia
elimination
Genes
Chloroquine
3 Downloads (Pure)

Plasmodium falciparum artemisinin resistance monitoring in Sabah, Malaysia: In vivo therapeutic efficacy and kelch13 molecular marker surveillance

Grigg, M. J., William, T., Piera, K. A., Rajahram, G. S., Jelip, J., Aziz, A., Menon, J., Marfurt, J., Price, R. N., Auburn, S., Barber, B. E., Yeo, T. W. & Anstey, N. M., 10 Dec 2018, In : Malaria Journal. 17, 1, p. 1-8 8 p., 463.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
File
Malaysia
Plasmodium falciparum
Parasites
Therapeutics
Malaria
2017
10 Downloads (Pure)

Challenges for achieving safe and effective radical cure of Plasmodium vivax: a round table discussion of the APMEN Vivax Working Group

Thriemer, K., Ley, B., Bobogare, A. B., Dysoley, L., Alam, M. S., Pasaribu, A. P., Sattabongkot-Prachumsri, J. S. P., Jambert, E., Domingo, G. J., Commons, R., Auburn, S., Marfurt, J., Devine, A., Aktaruzzaman, M. M., Sohel, N., Namgay, R. N., Drukpa, T., Sharma, S. N., Sarawati, E., Samad, I. & 47 others, Theodora, M., Nambanya, S., Ounekham, S., Mudin, R. N. B., Da Thakur, G., Makita, L. S., Deray, R., Lee, S. E., Boaz, L., Danansuriya, M. N., Mudiyanselage, S. D., Chinanonwait, N., Kitchakarn, S., Nausien, J., Naket, E., Duc, T. N., Do Manh, H., Hong, Y. S., Cheng, Q., Richards, J. S., Kusriastuti, R., Satyagraha, A. W., Noviyanti, R., Ding, X. C., Khan, W. A., Swe Phru, C., Guoding, Z., Qi, G., Kaneko, A., Miotto, O., Nguitragool, W., Roobsoong, W., Battle, K., Howes, R. E., Roca-Feltrer, A., Duparc, S., Bhowmick, I. P., Kenangalem, E., Bibit, J. A., Barry, A. E., Sintasath, D., Abeyasinghe, R., Sibley, C. H., McCarthy, J., Von Seidlein, L., Baird, J. K. & Price, R. N., 5 Apr 2017, In : Malaria Journal. 16, 141, p. 1-9 9 p., 141.

Research output: Contribution to journalMeeting AbstractResearchpeer-review

Open Access
File
Plasmodium vivax
Glucose-6-Phosphate
Primaquine
Point-of-Care Systems
Malaria
5 Downloads (Pure)

Chloroquine efficacy for Plasmodium vivax in Myanmar in populations with high genetic diversity and moderate parasite gene flow

Htun, M. W., Mon, N. C. N., Aye, K. M., Hlaing, C. M., Kyaw, M. P., Handayuni, I., Trimarsanto, H., Bustos, D., Ringwald, P., Price, R. N., Auburn, S. & Thriemer, K., 10 Jul 2017, In : Malaria Journal. 16, p. 1-13 13 p., 281.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
File
Myanmar
Plasmodium vivax
Gene Flow
Chloroquine
Parasites
6 Downloads (Pure)

Comparison of artemether-lumefantrine and chloroquine with and without primaquine for the treatment of Plasmodium vivax infection in Ethiopia: A randomized controlled trial

Abreha, T., Hwang, J., Thriemer, K., Tadesse, Y., Girma, S., Melaku, Z., Assef, A., Kassa, M., Chatfield, M. D., Landman, K. Z., Chenet, S. M., Lucchi, N. W., Udhayakumar, V., Zhou, Z., Shi, Y. P., Kachur, S. P., Jima, D., Kebede, A., Solomon, H., Mekasha, A. & 7 others, Alemayehu, B. H., Malone, J. L., Dissanayake, G., Teka, H., Auburn, S., von Seidlein, L. & Price, R. N., 16 May 2017, In : PLoS Medicine. 14, 5, p. 1-17 17 p., e1002299.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
File
Primaquine
Plasmodium vivax
Ethiopia
Chloroquine
Malaria

Dissecting malaria biology and epidemiology using population genetics and genomics

Auburn, S. & Barry, A. E., Feb 2017, In : International Journal for Parasitology. 47, 2-3, p. 77-85 9 p.

Research output: Contribution to journalReview articleResearchpeer-review

Metagenomics
Population Genetics
Malaria
Parasites
Epidemiology
5 Downloads (Pure)

Genetic micro-epidemiology of malaria in Papua Indonesia: Extensive P. vivax diversity and a distinct subpopulation of asymptomatic P. falciparum infections

Pava, Z., Noviyanti, R., Handayuni, I., Trimarsanto, H., Trianty, L., Burdam, F. H., Kenangalem, E., Utami, R. A. S., Tirta, Y. K., Coutrier, F., Poespoprodjo, J. R., Price, R. N., Marfurt, J. & Auburn, S., 1 May 2017, In : PLoS One. 12, 5, p. 1-13 13 p., e0177445.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
File
Epidemiology
Indonesia
Molecular Epidemiology
malaria
genotyping
8 Downloads (Pure)

Genomic characterization of recrudescent plasmodium malariae after treatment with artemether/lumefantrine

Rutledge, G. G., Marr, I., Huang, G. K. L., Auburn, S., Marfurt, J., Sanders, M., White, N. J., Berriman, M., Newbold, C. I., Anstey, N. M., Otto, T. D. & Price, R. N., 1 Aug 2017, In : Emerging Infectious Diseases. 23, 8, p. 1300-1307 8 p.

Research output: Contribution to journalReview articleResearchpeer-review

Open Access
File
Plasmodium malariae
Malaria
Clone Cells
Infection
Bites and Stings
2 Downloads (Pure)

Molecular analysis demonstrates high prevalence of chloroquine resistance but no evidence of artemisinin resistance in Plasmodium falciparum in the Chittagong Hill Tracts of Bangladesh

Alam, M. S., Ley, B., Nima, M. K., Johora, F. T., Hossain, M. E., Thriemer, K., Auburn, S., Marfurt, J., Price, R. N. & Khan, W. A., 15 Aug 2017, In : Malaria Journal. 16, p. 1-6 6 p., 335.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
File
Bangladesh
Chloroquine
Plasmodium falciparum
Antimalarials
Mutation
4 Downloads (Pure)

Passively versus actively detected malaria: Similar genetic diversity but different complexity of infection

Pava, Z., Handayuni, I., Trianty, L., Utami, R. A. S., Tirta, Y. K., Puspitasari, A. M., Burdam, F., Kenangalem, E., Wirjanata, G., Kho, S., Trimarsanto, H., Anstey, N., Poespoprodjo, J. R., Noviyanti, R., Price, R. N., Marfurt, J. & Auburn, S., Dec 2017, In : American Journal of Tropical Medicine and Hygiene. 97, 6, p. 1788-1796 9 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
File
Malaria
Plasmodium vivax
Plasmodium falciparum
Infection
Parasites

Plasmodium malariae and P. ovale genomes provide insights into malaria parasite evolution

Rutledge, G. G., Bohme, U., Sanders, M., Reid, A., Cotton, J. A., Maiga-Ascofare, O., Djimde, A., Apinjoh, T. O., Amenga-Etego, L., Manske, M., Barnwell, J., Renaud, F., Ollomo, B., Prugnolle, F., Anstey, N., Auburn, S., Price, R., McCarthy, J., Kwiatkowski, D., Newbold, C. & 2 others, Berriman, M. & Otto, T., 2017, In : Nature. 542, 7639, p. 101-104 4 p.

Research output: Contribution to journalLetterResearchpeer-review

Open Access
Genes
Proteins
Blood
Cells
Parasites
4 Downloads (Pure)

VivaxGEN: An open access platform for comparative analysis of short tandem repeat genotyping data in Plasmodium vivax Populations

Trimarsanto, H., Benavente, E. D., Noviyanti, R., Utami, R. A. S., Trianty, L., Pava, Z., Getachew, S., Kim, J-Y., Goo, Y-K., Wangchuck, S., Liu, Y., Gao, Q., Dowd, S., Cheng, Q., Clark, T. G., Price, R. N. & Auburn, S., 31 Mar 2017, In : PLoS Neglected Tropical Diseases. 11, 3, p. 1-12 12 p., e0005465.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
File
Plasmodium vivax
Population Genetics
Microsatellite Repeats
Alleles
Population
2016
7 Downloads (Pure)

Admixture into and within sub-Saharan Africa

Busby, G. B. J., Band, G., Le, Q. S., Jallow, M., Bougama, E., Mangano, V. D., Amenga-Etego, L. N., Enimil, A., Apinjoh, T. O., Ndila, C. M., Manjurano, A., Nyirongo, V., Doumba, O., Rockett, K. A., Kwiatkowski, D. P., Spencer, C. C. A., Vanderwal, A., Elzein, A., Nyika, A., Mendy, A. & 231 others, Miles, A., Diss, A., Kerasidou, A., Green, A., Jeffreys, A. E., MacInnis, B., Hughes, C., Moyes, C., Hubbart, C., Malangone, C., Potter, C., Mead, D., Barnwell, D., Jyothi, D., Drury, E., Somaskantharajah, E., Hilton, E., Leffler, E., Maslen, G., Busby, G., Clarke, G. M., Ragoussis, I., Garcia, J. A., Rogers, J., deVries, J., Shelton, J. M. G., Ragoussis, J., Stalker, J., Rodford, J., O'Brien, J., Evans, J., Rowlands, K., Cook, K., Fitzpatrick, K., Kivinen, K., Small, K., Johnson, K. J., Hart, L., Manske, M., McCreight, M., Stevens, M., Pirinen, M., Hennsman, M., Parker, M., SanJoaquin, M., Seplúveda, N., Cook, O., Miotto, O., Deloukas, P., Craik, R., Wrigley, R., Watson, R., Pearson, R. D., Hutton, R., Oyola, S., Auburn, S., Shah, S., Le, S. Q., Molloy, S., Bull, S., Campino, S., Clark, T. G., Ruano-Rubio, V., Cornelius, V., Teo, Y. Y., Corran, P., Silva, N., Risley, P., Doyle, A., Evans, J., Horstmann, R., Plowe, C., Duffy, P., Carucci, D., Gottleib, M., Tall, A., Ly, A. B., Dolo, A., Sakuntabhai, A., Puijalon, O., Bah, A., Camara, A., Sadiq, A., Abie Khan, A., Jobarteh, A., Mendy, A., Ebonyi, A., Danso, B., Taal, B., Casals-Pascual, C., Conway, D. J., Onykwelu, E., Sisay-Joof, F., Sirugo, G., Kanyi, H., Njie, H., Obu, H., Saine, H., Sambou, I., Abubakar, I., Njie, J., Jaiteh, J., Bojang, K. A., Jammeh, K., Sabally-Ceesay, K., Manneh, L., Camara, L., Yamoah, L., Njie, M., Pinder, M., Jallow, M., Aiyegbo, M., Jasseh, M., Keita, M. L., Saidy-Khan, M., Ceesay, N., Rasheed, O., Ceesay, P. L., Esangbedo, P., Cole-Ceesay, R., Olaosebikan, R., Correa, S., Njie, S., Usen, S., Dibba, Y., Barry, A., Djimdé, A., Sall, A. H., Abathina, A., Niangaly, A., Dembele, A., Poudiougou, B., Diarra, E., Bamba, K., Thera, M. A., Doumbo, O., Toure, O., Konate, S., Sissoko, S., Diakite, M., Konate, A. T., Modiano, D., Bougouma, E. C., Bancone, G., Ouedraogo, I. N., Simpore, J., Sirima, S. B., Troye-Blomberg, M., Oduro, A. R., Hodgson, A. V. O., Ghansah, A., Nkrumah, F., Atuguba, F., Koram, K. A., Wilson, M. D., Ansah, N. A., Mensah, N., Ansah, P. A., Anyorigiya, T., Asoala, V., Rogers, W. O., Akoto, A. O., Ofori, A. O., Ansong, D., Sambian, D., Asafo-Agyei, E., Sylverken, J., Antwi, S., Agbenyega, T., Orimadegun, A. E., Amodu, F. A., Oni, O., Omotade, O. O., Amodu, O., Olaniyan, S., Ndi, A., Yafi, C., Achidi, E. A., Mbunwe, E., Anchang-Kimbi, J., Mugri, R., Besingi, R., Apinjoh, T. O., Titanji, V., Elhassan, A., Hussein, A., Mohamed, H., Elhassan, I., Ibrahim, M., Kokwaro, G., Oluoch, T., Macharia, A., Newton, C., Opi, D. H., Kamuya, D., Bauni, E., Marsh, K., Peshu, N., Molyneux, S., Uyoga, S., Williams, T. N., Marsh, V., Nadjm, B., Maxwell, C., Drakeley, C., Riley, E., Mtei, F., Mtove, G., Wangai, H., Reyburn, H., Joseph, S., Ishengoma, D., Lemnge, M., Mutabingwa, T., Makani, J., Cox, S., Phiri, A., Munthali, A., Kachala, D., Njiragoma, L., Molyneux, M. E., Moore, M., Ntunthama, N., Pensulo, P., Taylor, T., Carter, R., Fernando, D., Karunaweera, N., Dewasurendra, R., Suriyaphol, P. & Malaria Genomic Epidemiology Network, 21 Jun 2016, In : eLife. 5, JUN2016, p. 1-44 44 p., e15266.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
File
Africa South of the Sahara
Haplotypes
Gene Flow
Genes
Population
6 Downloads (Pure)

A new Plasmodium vivax reference sequence with improved assembly of the subtelomeres reveals an abundance of pir genes

Auburn, S., Böhme, U., Steinbiss, S., Trimarsanto, H., Hostetler, J., Sanders, M., Gao, Q., Nosten, F., Newbold, C. I., Berriman, M., Price, R. N. & Otto, T. D., 15 Nov 2016, In : Wellcome Open Research. 1, 4, p. 1-12 12 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
File
Plasmodium vivax
Plasmodium
Parasites
South America
Genes
7 Downloads (Pure)

Dihydrofolate-reductase mutations in plasmodium knowlesi appear unrelated to selective drug pressure from putative human-to-human transmission in Sabah, Malaysia

Grigg, M., Barber, B., Marfurt, J., Imwong, M., William, T., Bird, E., Piera, K., Aziz, A., Boonyuen, U., Drakeley, C., Cox, J., White, N. J., Cheng, Q., Yeo, T., Auburn, S. & Anstey, N., 2016, In : PLoS One. 11, 3, p. 1-19 19 p., e0149519.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
File
Plasmodium knowlesi
dihydrofolate reductase
Tetrahydrofolate Dehydrogenase
Malaysia
Borneo

Efficacy of artesunate-mefloquine for chloroquine-resistant plasmodium vivax malaria in Malaysia: An open-label, randomized, controlled trial

Grigg, M., Williams, T., Menon, J., Barber, B., Wilkes, C., Rajahram, G., Edstein, M., Auburn, S., Price, R., Yeo, T. & Anstey, N., 1 Jun 2016, In : Clinical Infectious Diseases. 62, 11, p. 1403-1411 9 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
Vivax Malaria
Mefloquine
Malaysia
Chloroquine
Randomized Controlled Trials

Expression of Plasmodium vivax crt-o is related to parasite stage but not ex vivo chloroquine susceptibility

Pava, Z., Handayuni, I., Wirjanata, G., To, S., Trianty, L., Noviyanti, R., Poespoprodjo, J. R., Auburn, S., Price, R. & Marfurt, J., Jan 2016, In : Antimicrobial Agents and Chemotherapy. 60, 1, p. 361-367 7 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
Plasmodium vivax
Chloroquine
Parasites
Amodiaquine
Pharmaceutical Preparations
12 Downloads (Pure)

Further evidence of increasing diversity of Plasmodium vivax in the Republic of Korea in recent years

Kim, J-Y., Goo, Y-K., Zo, Y. G., Ji, S-Y., Trimarsanto, H., To, S., Clark, T., Price, R. & Auburn, S., 2016, In : PLoS One. 11, 3, p. 1-16 16 p., e0151514.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
File
Plasmodium vivax
Republic of Korea
South Korea
Tandem Repeat Sequences
malaria
10 Downloads (Pure)

G6PD deficiency and antimalarial efficacy for uncomplicated malaria in Bangladesh: A prospective observational study

Ley, B., Alam, MS., Ley-Thriemer, K., Hossain, M., Kibria, MG., Auburn, S., Poirot, E., Price, R. & Khan, W., 2016, In : PLoS One. 11, 4, p. 1-15 15 p., e0154015.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
File
Primaquine
Glucosephosphate Dehydrogenase Deficiency
antimalarials
Bangladesh
Antimalarials

Genomic analysis of local variation and recent evolution in Plasmodium vivax

Pearson, R. D., Amato, R., Auburn, S., Miotto, O., Almagro-Garcia, J., Amaratunga, C., Suon, S., Mao, S., Noviyanti, R., Trimarsanto, H., Marfurt, J., Anstey, N. M., WILLIAM, T., Boni, M. F., Dolecek, C., Tran, H. T., White, N. J., Michon, P., Siba, P., Tavul, L. & 24 others, Harrison, G., Barry, A. E., Mueller, I., Ferreira, M. U., Karunaweera, N., Randrianarivelojosia, M., Gao, Q., Hubbart, C., Hart, L., Jeffery, B., Drury, E., Mead, D., Kekre, M., Campino, S., Manske, M., Cornelius, V. J., MacInnis, B., Rockett, K. A., Miles, A., Rayner, J. C., Fairhurst, R. M., Nosten, F., Price, R. N. & Kwiatkowski, D. P., 1 Aug 2016, In : Nature Genetics. 48, 8, p. 959-964 6 p.

Research output: Contribution to journalArticleResearchpeer-review

Plasmodium vivax
Malaria
Parasites
Genome
Population

Genomic Analysis Reveals a Common Breakpoint in Amplifications of the Plasmodium vivax Multidrug Resistance 1 Locus in Thailand

Auburn, S., Serre, D., Pearson, R. D., Amato, R., Sriprawat, K., To, S., Handayuni, I., Suwanarusk, R., Russell, B., Drury, E., Stalker, J., Miotto, O., Kwiatkowski, D., Nosten, F. & Price, R., 2016, In : Journal of Infectious Diseases. 214, 8, p. 1235-1242 8 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
Mefloquine
Plasmodium vivax
Multiple Drug Resistance
Thailand
Plasmodium falciparum
7 Downloads (Pure)

Genomic epidemiology of artemisinin resistant malaria

Amato, R., Miotto, O., Woodrow, C. J., Almagro-Garcia, J., Sinha, I., Campino, S., Mead, D., Drury, E., Kekre, M., Sanders, M., Amambua-Ngwa, A., Amaratunga, C., Amenga-Etego, L., Andrianaranjaka, V., Apinjoh, T., Ashley, E., Auburn, S., Awandare, G. A., Baraka, V., Barry, A. & 77 others, Boni, M. F., Borrmann, S., Bousema, T., Branch, O., Bull, P. C., Chotivanich, K., Conway, D. J., Craig, A., Day, N. P., Djimdé, A., Dolecek, C., Dondorp, A. M., Drakeley, C., Duffy, P., Echeverry, D. F., Egwang, T. G., Fairhurst, R. M., Faiz, A., Fanello, C. I., Hien, T. T., Hodgson, A., Imwong, M., Ishengoma, D., Lim, P., Lon, C., Marfurt, J., Marsh, K., Mayxay, M., Michon, P., Mobegi, V., Mokuolu, O. A., Montgomery, J., Mueller, I., Kyaw, M. P., Newton, P. N., Nosten, F., Noviyanti, R., Nzila, A., Ocholla, H., Oduro, A., Onyamboko, M., Ouedraogo, J. B., Phyo, A. P. P., Plowe, C., Price, R. N., Pukrittayakamee, S., Randrianarivelojosia, M., Ringwald, P., Ruiz, L., Saunders, D., Shayo, A., Siba, P., Takala-Harrison, S., Thanh, T. N. N., Thathy, V., Verra, F., Wendler, J., White, N. J., Ye, H., Cornelius, V. J., Giacomantonio, R., Muddyman, D., Henrichs, C., Malangone, C., Jyothi, D., Pearson, R. D., Rayner, J. C., McVean, G., Rockett, K. A., Miles, A., Vauterin, P., Jeffery, B., Manske, M., Stalker, J., Macinnis, B., Kwiatkowski, D. P. & MalariaGEN Plasmodium falciparum Community Project, 4 Mar 2016, In : eLife. 5, MARCH2016, p. 1-29 29 p., e08714.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
File
Epidemiology
Southeastern Asia
Malaria
Geographical regions
Mutation
6 Downloads (Pure)

Molecular epidemiology of P. vivax in Iran: High diversity and complex sub-structure using neutral markers, but no evidence of Y976F mutation at pvmdr1

Hamedi, Y., Sharifi-Sarasiabi, K., Dehghan, F., Safari, R., To, S., Handayuni, I., Trimarsanto, H., Price, R. N. & Auburn, S., 1 Nov 2016, In : PLoS One. 11, 11, e0166124.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
File
molecular epidemiology
Molecular Epidemiology
Iran
Chloroquine
mutation
6 Downloads (Pure)

Submicroscopic and asymptomatic plasmodium parasitaemia associated with significant risk of anaemia in Papua, Indonesia

Pava, Z., Burdam, F. H., Handayuni, I., Trianty, L., Utami, R. A. S., Tirta, Y. K., Kenangalem, E., Lampah, D., Kusuma, A., Wirjanata, G., Kho, S., Simpson, J. A., Auburn, S., Douglas, N. M., Noviyanti, R., Anstey, N. M., Poespoprodjo, J. R., Marfurt, J. & Price, R. N., 1 Oct 2016, In : PLoS One. 11, 10, e0165340.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
File
Plasmodium
Indonesia
Parasitemia
parasitemia
odds ratio
4 Downloads (Pure)

Transfusion-transmitted severe Plasmodium knowlesi malaria in a splenectomized patient with beta-thalassaemia major in Sabah, Malaysia: A case report

Bird, E., Parameswaran, U., Williams, T., Khoo, T., Grigg, M., Aziz, A., Marfurt, J., Yeo, T., Auburn, S., Anstey, N. & Barber, B., 2016, In : Malaria Journal. 15, 1, p. 1-6 6 p., 357.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
File
Plasmodium knowlesi
Plasmodium malariae
beta-Thalassemia
Malaysia
Malaria
4 Downloads (Pure)

Where chloroquine still works: The genetic make-up and susceptibility of Plasmodium vivax to chloroquine plus primaquine in Bhutan

Wangchuk, S., Drukpa, T., Penjor, K., Peldon, T., Dorjey, Y., Dorji, K., Chhetri, V., Trimarsanto, H., To, S., Murphy, A., von Seidlein, L., Price, R., Ley-Thriemer, K. & Auburn, S., 2016, In : Malaria Journal. 15, 1, p. 1-11 11 p., 277.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
File
Bhutan
Primaquine
Plasmodium vivax
Chloroquine
Population
2015

A novel locus of resistance to severe malaria in a region of ancient balancing selection

Band, G., Rockett, K. A., Spencer, C. C. A., Kwiatkowski, D. P., Si Le, Q., Clarke, G. M., Kivinen, K., Leffler, E. M., Cornelius, V., Conway, D. J., Williams, T. N., Taylor, T., Bojang, K. A., Doumbo, O., Thera, M. A., Modiano, D., Sirima, S. B., Wilson, M. D., Koram, K. A., Agbenyega, T. & 47 others, Achidi, E., Marsh, K., Reyburn, H., Drakeley, C., Riley, E., Molyneux, M., Jallow, M., Pinder, M., Toure, O. B., Konate, S., Sissoko, S., Bougouma, E. C., Mangano, V. D., Amenga-Etego, L. N., Ghansah, A. K., Hodgson, A. V. O., Wilson, M. D., Ansong, D., Enimil, A., Evans, J., Apinjoh, T. O., Macharia, A., Ndila, C. M., Newton, C., Peshu, N., Uyoga, S., Manjurano, A., Kachala, D., Nyirongo, V., Mead, D., Drury, E., Auburn, S., Campino, S. G., MacInnis, B., Stalker, J., Gray, E., Hubbart, C., Jeffreys, A. E., Rowlands, K., Mendy, A., Craik, R., Fitzpatrick, K., Molloy, S., Hart, L., Hutton, R., Kerasidou, A. & Johnson, K. J., 2015, In : Nature. 526, 7572, p. 253-257 5 p.

Research output: Contribution to journalArticleResearchpeer-review

Gene encoding
Genes
Polymorphism
Hemoglobin
Cell membranes
3 Downloads (Pure)

Chloroquine efficacy for Plasmodium vivax malaria treatment in southern Ethiopia

Getachew, S., Ley-Thriemer, K., Auburn, S., Abera, A., Gadisa, E., Aseffa, A., Price, R. & Petros, B., 2015, In : Malaria Journal. 14, 1, p. 1-8 8 p., 525.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
File
Vivax Malaria
Ethiopia
Chloroquine
Treatment Failure
Therapeutics
5 Downloads (Pure)

Contrasting Transmission Dynamics of Co-endemic Plasmodium vivax and P. falciparum: Implications for Malaria Control and Elimination

Noviyanti, R., Farah, C., Utami, R. A. S., Trimarsanto, H., Tirta, Y. K., Trianty, L., Kusuma, A., Sutanto, A., Kosasih, A., Kusriastuti, Hawley, W. A., Laihad, F., Lobo, N., Marfurt, J., Clark, T., Price, R. & Auburn, S., 2015, In : PLoS Neglected Tropical Diseases. 9, 5 1, p. 1-19 19 p., e0003739.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
File
Plasmodium vivax
Falciparum Malaria
Malaria
Indonesia
Linkage Disequilibrium
7 Downloads (Pure)

Genetic determinants of anti-malarial acquired immunity in a large multi-centre study

Shelton, J. M. G., Corran, P., Risley, P., Silva, N., Hubbart, C., Jeffreys, A., Rowlands, K., Craik, R., Cornelius, V., Hensmann, M., Molloy, S., Sepulveda, N., Clark, T. G., Band, G., Clarke, G. M., Spencer, C. C. A., Kerasidou, A., Campino, S., Auburn, S., Tall, A. & 39 others, Ly, A. B., Mercereau-Puijalon, O., Sakuntabhai, A., Djimdé, A., Maiga, B., Touré, O., Doumbo, O. K., Dolo, A., Troye-Blomberg, M., Mangano, V. D., Verra, F., Modiano, D., Bougouma, E., Sirima, S. B., Ibrahim, M., Hussain, A., Eid, N., Elzein, A., Mohammed, H., Elhassan, A., Elhassan, I., Williams, T. N., Ndila, C., Macharia, A., Marsh, K., Manjurano, A., Reyburn, H., Lemnge, M., Ishengoma, D., Carter, R., Karunaweera, N., Fernando, D., Dewasurendra, R., Drakeley, C. J., Riley, E. M., Kwiatkowski, D. P., Rockett, K. A., MalariaGEN Consortium & MalariaGEN Consortium, 2015, In : Malaria Journal. 14, 1, p. 1-18 18 p., 833.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
File
Antimalarials
Adaptive Immunity
Malaria
Antibodies
Merozoite Surface Protein 1
9 Downloads (Pure)

Targeting vivax malaria in the Asia Pacific: The Asia Pacific Malaria Elimination Network Vivax Working Group

Anstey, N. M., Auburn, S. A., Kevin, B. K., Battle, K. E., Bobogare, A. B., Chancellor, A. C., Chasombat, S. C., Cheng, Q. C., Domingo, G. J., Drakeley, C. J., Drukpa, T. D., Dysoley, L., Espino, F. E., Gething, P. W., Ghimire, P. G., Gosling, R. D., Grewal-Daumerie, P. G. D., Hay, S. I., Howes, R. E., Hwang, J. M. & 26 others, Karim, J. K., Khan, W. A., Kim, J-Y., Ley, B. L., Mannion, K. M., McCarthy, J. M., Keong, W. M., Mueller, M. I., Namgay, R. N., Price, R. N., Qi, G. Q., Rebueno, M. R., Reeder, J. R., Richards, J. R., Sattabongkot-Prachumsri, J. S. P., Shanks, G. D., Sibley, C. H., Surya, A. S., Taleo, G. T., Thang, N. D., Thongpaseuth, V. T., Ley-Thriemer, K., Trimarsanto, H. T., Vestergaard, L. S., Seidelein, L. V. & Whittaker, M. W., 1 Dec 2015, In : Malaria Journal. 14, 1, p. 1-11 11 p., 484.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
File
Vivax Malaria
Malaria
Professional Competence
Plasmodium vivax
Evidence-Based Practice
3 Downloads (Pure)

Variation in complexity of infection and transmission stability between neighbouring populations of Plasmodium vivax in Southern Ethiopia

Getachew, S., To, S., Trimarsanto, H., Ley-Thriemer, K., Clark, TG., Petros, B., Aseffa, A., Price, R. & Auburn, S., 2015, In : PLoS One. 10, p. 1-15 15 p., e0140780 .

Research output: Contribution to journalArticleResearchpeer-review

Open Access
File
Plasmodium vivax
Infectious Disease Transmission
Ethiopia
malaria
Parasites
2014
9 Downloads (Pure)

Genetic diversity and population structure of Plasmodium vivax in Central China

Liu, Y., Auburn, S., Cao, J., Trimarsanto, H., Zhou, H., Gray, K-A., Clark, T., Price, R., Cheng, Q., Huang, R. & Gao, Q., 2014, In : Malaria Journal. 13, 1, p. 1-12 12 p., 262.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
File
Plasmodium vivax
China
Haplotypes
Population
Parasites
2013
Open Access
Plasmodium knowlesi
Vivax Malaria
Plasmodium vivax
Falciparum Malaria
Malaysia
3 Downloads (Pure)

Effective Preparation of Plasmodium vivax Field Isolates for High-Throughput Whole Genome Sequencing

Auburn, S., Marfurt, J., Maslen, G., Campino, S., Ruano-Rubio, V., Manske, M., Machunter, B., Kenangalem, E., Noviyanti, R., Trianty, L., Sebayang, B., Wirjanata, G., Sriprakash, K., Alcock, D., MacInnes, B., Miotto, O., Clark, T., Russell, B., Anstey, N., Nosten, F. & 2 others, Kwiatkowski, D. & Price, R., 2013, In : PLoS One. 8, 1, p. 1-11 11 p., e53160.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
File
Plasmodium vivax
Genes
Throughput
Genome
genome

Genetic loci associated with delayed clearance of Plasmodium falciparum following artemisinin treatment in Southeast Asia

Takala-Harrison, S., Clark, T., Jacob, C., Cummings, MP., Miotto, O., Dondorp, A., Fukuda, M., Nosten, F., Noedl, H., Imwong, M., Bethell, D., Se, Y., Lon, C., Tyner, SD., Saunders, D., Socheat, D., Ariey, F., Phyo, A. P., Starzengruber, P., Fuehrer, H. & 19 others, Swoboda, P., Stepniewska, K., Flegg, J., Arze, C., Cerqueira, GC., Silva, J., Ricklefs, SM., Porcella, S., Stephens, RM., Adams, M., Kenefic, L., Campino, S., Auburn, S., MacInnes, B., Kwiatkowski, D., Su, X-Z., White, N. J., RINGWALD, P. & Plowe, C., 2013, In : Proceedings of the National Academy of Sciences of the United States of America. 110, 1, p. 240-245 6 p.

Research output: Contribution to journalArticleResearchpeer-review

Southeastern Asia
Genetic Loci
Plasmodium falciparum
Single Nucleotide Polymorphism
Cambodia
8 Downloads (Pure)

Genome-wide screen identifies new candidate genes associated with artemisinin susceptibility in Plasmodium falciparum in Kenya

Borrmann, S., Straimer, J., Mwai, L., Abdi, A., Rippert, A., Okombo, J., Muriithi, S., Sasi, P., Kortok, M. M., Lowe, B., Campino, S., Assefa, S., Auburn, S., Manske, M., Maslen, G., Peshu, N., Kwiatkowski, D., Marsh, K., Nzila, A. & Clark, T., 2013, In : Scientific Reports. 3, p. 1-10 10 p., 3318.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
File
dihydroartemisinin
Kenya
Plasmodium falciparum
Artemisinins
Genome

Multiple populations of artemisinin-resistant Plasmodium falciparum in Cambodia

Miotto, O., Almagro-Garcia, J., Manske, M., MacInnis, B., Campino, S., Rockett, K. A., Amaratunga, C., Lim, P., Suon, S., Sreng, S., Anderson, J. M., Duong, S., Nguon, C., Chuor, C. M., Saunders, D., Se, Y., Lon, C., Fukuda, M. M., Amenga-Etego, L., Hodgson, A. V. O. & 42 others, Asoala, V., Imwong, M., Takala-Harrison, S., Nosten, F., Su, X. Z., Ringwald, P., Ariey, F., Dolecek, C., Hien, T. T., Boni, M. F., Thai, C. Q., Amambua-Ngwa, A., Conway, D. J., Djimdé, A. A., Doumbo, O. K., Zongo, I., Ouedraogo, J. B., Alcock, D., Drury, E., Auburn, S., Koch, O., Sanders, M., Hubbart, C., Maslen, G., Ruano-Rubio, V., Jyothi, D., Miles, A., O'Brien, J., Gamble, C., Oyola, S. O., Rayner, J. C., Newbold, C. I., Berriman, M., Spencer, C. C. A., McVean, G., Day, N. P., White, N. J., Bethell, D., Dondorp, A. M., Plowe, C. V., Fairhurst, R. M. & Kwiatkowski, D. P., 2013, In : Nature Genetics. 45, 6, p. 648-655 8 p.

Research output: Contribution to journalArticleResearchpeer-review

Cambodia
Plasmodium falciparum
Population
Parasites
Founder Effect
10 Downloads (Pure)

Plasmodium vivax Population Structure and Transmission Dynamics in Sabah Malaysia

Abdullah, N., Barber, B., William, T., Norahmad, N., Satsu, U., Muniandy, P., Ismail, Z., Grigg, M., Jelip, J., Piera, K., Von Seidlein, L., Yeo, T., Anstey, N., Price, R. & Auburn, S., 2013, In : PLoS One. 8, 12, p. 1-10 10 p., e82553.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
File
Plasmodium vivax
Malaysia
Borneo
population structure
Recurrence
116 Downloads (Pure)

Review of key knowledge gaps in glucose-6-phosphate dehydrogenase deficiency detection with regard to the safe clinical deployment of 8-aminoquinoline treatment regimens: A workshop report

Von Seidlein, L., Auburn, S., Espino, F., Shanks, D., Cheng, Q., McCarthy, J., Baird, J. K., Moyes, C., Howes, R., Menard, D., Bancone, Winasti-Satuahraha, A., Vestergaard, L., Green, J., Domingo, G., Yeung, S. & Price, R., 2013, In : Malaria Journal. 12, 1, p. 112-1-112-12 12 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
File
Glucosephosphate Dehydrogenase Deficiency
Primaquine
Glucosephosphate Dehydrogenase
Education
Malaria
2012

Analysis of Plasmodium falciparum diversity in natural infections by deep sequencing

Manske, M., Miotto, O., Campino, S., Auburn, S., Almagro-Gracia, J., Maslen, G., O'Brien, J., Djimde, A., Doumbo, O., Zongo, I., Ouedraogo, J., Michon, P., Mueller, I., Siba, P., Nzila, A., Borrman, S., Kiara, S., Marsh, K., Jiang, H., Su, X-Z. & 36 others, Amaratunga, C., Fairhurst, R., Socheat, D., Nosten, F., Imwong, M., White, N. J., Sanders, M., Anastasi, E., Alcock, D., Drury, E., Oyola, S., Quail, M., Turner, D., Ruano-Rubio, V., Jyothi, D., Amenga-Etego, L., Hubbart, C., Jeffreys, A., Rowlands, K., Sutherland, C., Roper, C., Mangano, V., Modiano, D., Tan, J., Ferdig, M., Amambua-Ngwa, A., Conway, D., Takala-Harrison, S., Plowe, C., Rayner, J., Rockett, K., Clark, T., Newbold, C., Berriman, M., MacInnis, B. & Kwiatkowski, D., 19 Jul 2012, In : Nature. 487, p. 375-379 5 p.

Research output: Contribution to journalArticleResearchpeer-review

Genes
Population distribution
Public health
Nucleotides
Polymorphism
3 Downloads (Pure)

Characterization of within-host Plasmodium falciparum diversity using next-generation sequence data

Auburn, S., Campino, S., Miotto, O., Djimde, A., Zongo, I., Manske, M., Maslen, G., Mangano, V., Alcock, D., MacInnis, B., Rockett, K., Clark, T., Doumbo, O., Ouedraogo, J. & Kwiatkowski, D., 2012, In : PLoS One. 7, 2, p. 1-6 6 p., e32891.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
File
Plasmodium falciparum
Genes
Statistics
Molecules
Infection

Phenotypic and genotypic characterisation of drug-resistant Plasmodium vivax

Price, R., Auburn, S., Marfurt, J. & Cheng, Q., 2012, In : Trends in Parasitology. 28, 11, p. 522-529 8 p.

Research output: Contribution to journalArticleResearchpeer-review

Plasmodium vivax
Drug Resistance
Clinical Trials
Pharmaceutical Preparations
Parasites
15 Downloads (Pure)

Using CF11 cellulose columns to inexpensively and effectively remove human DNA from Plasmodium falciparum-infected whole blood samples

Venkatesan, M., Amaratunga, C., Campino, S., Auburn, S., Koch, O., Lim, P., Uk, S., Socheat, D., Kwiatkowski, D., Fairhurst, R. & Plowe, C., 2012, In : Malaria Journal. 11, 41, p. 1-7 7 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
File
Plasmodium falciparum
Cellulose
DNA
Malaria
Parasites

VarB: A variation browsing and analysis tool for variants derived from next-generation sequencing data

Preston, M. D., Manske, M., Horner, N., Assefa, S., Campino, S., Auburn, S., Zongo, I., Ouedraogo, J. B., Nosten, F., Anderson, T. & Clark, T. G., Nov 2012, In : Bioinformatics. 28, 22, p. 2983-2985 3 p.

Research output: Contribution to journalComment/debateResearchpeer-review

Open Access
Antimalarials
Browsing
Nucleotides
Polymorphism
Sequencing
2011
4 Downloads (Pure)

An effective method to purify Plasmodium falciparum DNA directly from clinical blood samples for whole genome high-throughput sequencing

Auburn, S., Campino, S., Clark, T., Djimde, A., Zongo, I., Pinches, R., Manske, M., Mangano, V., Alcock, D., Anastasi, E., Maslen, G., MacInnis, B., Rockett, K., Modiana, D., Newbold, C., Doumbo, O., Ouedraogo, J. & Kwiatkowski, D., 2011, In : PLoS One. 6, 7, p. 1-8 8 p., e22213.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
File
Plasmodium falciparum
Blood
Genes
Plasmodium
Throughput
6 Downloads (Pure)

Drug-resistant genotypes and multi-clonality in Plasmodium falciparum analysed by direct genome sequencing from peripheral blood of malaria patients

Robinson, T., Campino, S., Auburn, S., Assefa, S., Polley, S., Manske, M., MacInnis, B., Rockett, K., Maslen, G., Sanders, M., Quail, M., Chiodini, P., Kwiatkowski, D., Clark, T. & Sutherland, C., 2011, In : PLoS One. 6, 8, p. 1-11 11 p., e23204.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
File
Plasmodium falciparum
malaria
Malaria
Blood
Clone Cells