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2019

3,3′-Disubstituted 5,5′-Bi(1,2,4-triazine) Derivatives with Potent in Vitro and in Vivo Antimalarial Activity

Xue, L., Shi, D. H., Harjani, J. R., Huang, F., Beveridge, J. G., Dingjan, T., Ban, K., Diab, S., Duffy, S., Lucantoni, L., Fletcher, S., Chiu, F. C. K., Blundell, S., Ellis, K., Ralph, S. A., Wirjanata, G., Teguh, S., Noviyanti, R., Chavchich, M., Creek, D. & 10 others, Price, R. N., Marfurt, J., Charman, S. A., Cuellar, M. E., Strasser, J. M., Dahlin, J. L., Walters, M. A., Edstein, M. D., Avery, V. M. & Baell, J. B., 14 Mar 2019, In : Journal of Medicinal Chemistry. 62, 5, p. 2485-2498 14 p.

Research output: Contribution to journalArticleResearchpeer-review

Antimalarials
Plasmodium falciparum
Plasmodium vivax
Triazines
Parasitemia
4 Downloads (Pure)

Analysis of erroneous data entries in paper based and electronic data collection

Ley, B., Rijal, K. R., Marfurt, J., Adhikari, N. R., Banjara, M. R., Shrestha, U. T., Thriemer, K., Price, R. N. & Ghimire, P., 22 Aug 2019, In : BMC Research Notes. 12, 1, p. 1-6 6 p., 537.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
File
Data acquisition
Nepal
Information Systems
Biomedical Research
Research Design

Circulating Neutrophil Extracellular Traps and Neutrophil Activation Are Increased in Proportion to Disease Severity in Human Malaria

Kho, S., Minigo, G., Andries, B., Leonardo, L., Prayoga, P., Poespoprodjo, J. R., Kenangalem, E., Price, R. N., Woodberry, T., Anstey, N. M. & Yeo, T. W., 15 Jun 2019, In : The Journal of infectious diseases. 219, 12, p. 1994-2004 11 p.

Research output: Contribution to journalArticleResearchpeer-review

Neutrophil Activation
Malaria
Parasitemia
Parasites
Plasmodium
1 Downloads (Pure)

Dealing with indeterminate outcomes in antimalarial drug efficacy trials: a comparison between complete case analysis, multiple imputation and inverse probability weighting

Dahal, P., Stepniewska, K., Guerin, P. J., D'Alessandro, U., Price, R. N. & Simpson, J. A., 27 Nov 2019, In : BMC Medical Research Methodology. 19, p. 1-17 17 p., 19.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
File
Antimalarials
Recurrence
Infection
Likelihood Functions
Falciparum Malaria
2 Downloads (Pure)

Early and late mortality after malaria in young children in Papua, Indonesia

Patriani, D., Arguni, E., Kenangalem, E., Dini, S., Sugiarto, P., Hasanuddin, A., Lampah, D. A., Douglas, N. M., Anstey, N. M., Simpson, J. A., Price, R. N. & Poespoprodjo, J. R., 30 Oct 2019, In : BMC Infectious Diseases. 19, 1, 1 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
File
Indonesia
Malaria
Mortality
Plasmodium falciparum
Vivax Malaria

Efficacy and safety of intermittent preventive treatment and intermittent screening and treatment versus single screening and treatment with dihydroartemisinin–piperaquine for the control of malaria in pregnancy in Indonesia: a cluster-randomised, open-label, superiority trial

Ahmed, R., Poespoprodjo, J. R., Syafruddin, D., Khairallah, C., Pace, C., Lukito, T., Maratina, S. S., Asih, P. B. S., Santana-Morales, M. A., Adams, E. R., Unwin, V. T., Williams, C. T., Chen, T., Smedley, J., Wang, D., Faragher, B., Price, R. N. & ter Kuile, F. O., 1 Sep 2019, In : The Lancet Infectious Diseases. 19, 9, p. 973-987 15 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
Indonesia
Malaria
Safety
Pregnancy
Therapeutics
2 Downloads (Pure)

Evaluating antimalarial efficacy in single-armed and comparative drug trials using competing risk survival analysis: A simulation study

Dahal, P., Guerin, P. J., Price, R. N., Simpson, J. A. & Stepniewska, K., 17 May 2019, In : BMC Medical Research Methodology. 19, 1, p. 1-14 14 p., 107.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
File
Antimalarials
Survival Analysis
Pharmaceutical Preparations
Infection
Treatment Failure

Genomic Analysis of Plasmodium vivax in Southern Ethiopia Reveals Selective Pressures in Multiple Parasite Mechanisms

Auburn, S., Getachew, S., Pearson, R. D., Amato, R., Miotto, O., Trimarsanto, H., Zhu, S. J., Rumaseb, A., Marfurt, J., Noviyanti, R., Grigg, M. J., Barber, B., William, T., Goncalves, S. M., Drury, E., Sriprawat, K., Anstey, N. M., Nosten, F., Petros, B., Aseffa, A. & 3 others, McVean, G., Kwiatkowski, D. P. & Price, R. N., 1 Dec 2019, In : Journal of Infectious Diseases. 220, 11, p. 1738-1749 12 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
Plasmodium vivax
Ethiopia
Parasites
Chloroquine
Immune Evasion
1018 Downloads (Pure)

Growing evidence of Plasmodium vivax across malaria-endemic Africa

Twohig, K. A., Pfeffer, D. A., Baird, J. K., Price, R. N., Zimmerman, P. A., Hay, S. I., Gething, P. W., Battle, K. E. & Howes, R. E., 31 Jan 2019, In : PLoS Neglected Tropical Diseases. 13, 1, p. 1-16 16 p., e0007140.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
File
Vivax Malaria
Malaria
Plasmodium vivax
Plasmodium falciparum
Epidemiology
7 Downloads (Pure)

High risk of Plasmodium vivax malaria following splenectomy in Papua, Indonesia

Kho, S., Andries, B., Commons, R. J., Shanti, PAI., Kenangalem, E., Douglas, N. N., Simpson, J., Sugiarto, P., Anstey, N. & Price, R., 1 Jan 2019, In : Clinical Infectious Diseases. 68, 1, p. 51-60 10 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
File
Vivax Malaria
Indonesia
Splenectomy
Confidence Intervals
Malaria
2 Downloads (Pure)

Malaria morbidity and mortality following introduction of a universal policy of artemisinin-based treatment for malaria in Papua, Indonesia: A longitudinal surveillance study

Kenangalem, E., Poespoprodjo, J. R., Douglas, N. M., Burdam, F. H., Gdeumana, K., Chalfein, F., Prayoga, Thio, F., Devine, A., Marfurt, J., Waramori, G., Yeung, S., Noviyanti, R., Penttinen, P., Bangs, M. J., Sugiarto, P., Simpson, J. A., Soenarto, Y., Anstey, N. M. & Price, R. N., 29 May 2019, In : PLoS Medicine. 16, 5, p. 1-23 23 p., 1002815.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
File
Indonesia
Malaria
Longitudinal Studies
Morbidity
Mortality

Mapping the global endemicity and clinical burden of Plasmodium vivax, 2000–17: a spatial and temporal modelling study

Battle, K. E., Lucas, T. C. D., Nguyen, M., Howes, R. E., Nandi, A. K., Twohig, K. A., Pfeffer, D. A., Cameron, E., Rao, P. C., Casey, D., Gibson, H. S., Rozier, J. A., Dalrymple, U., Keddie, S. H., Collins, E. L., Harris, J. R., Guerra, C. A., Thorn, M. P., Bisanzio, D., Fullman, N. & 19 others, Huynh, C. K., Kulikoff, X., Kutz, M. J., Lopez, A. D., Mokdad, A. H., Naghavi, M., Nguyen, G., Shackelford, K. A., Vos, T., Wang, H., Lim, S. S., Murray, C. J. L., Price, R. N., Baird, J. K., Smith, D. L., Bhatt, S., Weiss, D. J., Hay, S. I. & Gething, P. W., 27 Jul 2019, In : The Lancet. 394, 10195, p. 332-343 12 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
Plasmodium vivax
Vivax Malaria
Malaria
Far East
Africa South of the Sahara

Performance of the Access Bio/CareStart rapid diagnostic test for the detection of glucose-6-phosphate dehydrogenase deficiency: A systematic review and meta-analysis

Ley, B., Winasti Satyagraha, A., Rahmat, H., von Fricken, M. E., Douglas, N. M., Pfeffer, D. A., Espino, F., von Seidlein, L., Henriques, G., Oo, N. N., Menard, D., Parikh, S., Bancone, G., Karahalios, A. & Price, R. N., 1 Dec 2019, In : PLoS Medicine. 16, 12, p. 1-15 15 p., e1002992.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
File
Glucosephosphate Dehydrogenase Deficiency
Routine Diagnostic Tests
Meta-Analysis
Spectrophotometry
Primaquine

Plasmodium falciparum activates CD16+ dendritic cells to produce TNF and IL-10 in subpatent malaria

Loughland, J. R., Woodberry, T., Boyle, M. J., Tipping, P. E., Piera, K. A., Amante, F. H., Kenangalem, E., Price, R. N., Engwerda, C. R., Anstey, N. M., McCarthy, J. S. & Minigo, G., 29 Jan 2019, In : The Journal of infectious diseases. 219, 4, p. 660-671 12 p., jiy555.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
Plasmodium falciparum
Interleukin-10
Dendritic Cells
Malaria
Tumor Necrosis Factor-alpha

Plasmodium falciparum Activates CD16+ Dendritic Cells to Produce Tumor Necrosis Factor and Interleukin-10 in Subpatent Malaria

Loughland, J. R., Woodberry, T., Boyle, M. J., Tipping, P. E., Piera, K. A., Amante, F. H., Kenangalem, E., Price, R. N., Engwerda, C. R., Anstey, N. M., McCarthy, J. S. & Minigo, G., 29 Jan 2019, In : The Journal of infectious diseases. 219, 4, p. 660-671 12 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
Plasmodium falciparum
Interleukin-10
Dendritic Cells
Malaria
Tumor Necrosis Factor-alpha

Risk of Plasmodium vivax parasitaemia after Plasmodium falciparum infection: a systematic review and meta-analysis

Commons, R. J., Simpson, J. A., Thriemer, K., Hossain, M. S., Douglas, N. M., Humphreys, G. S., Sibley, C. H., Guerin, P. J. & Price, R. N., Jan 2019, In : The Lancet Infectious Diseases. 19, 1, p. 91-101 11 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
File
Plasmodium vivax
Parasitemia
Plasmodium falciparum
Malaria
Meta-Analysis
8 Downloads (Pure)

Safety of primaquine in infants with Plasmodium vivax malaria in Papua, Indonesia

Setyadi, A., Arguni, E., Kenangalem, E., Hasanuddin, A., Lampah, D. A., Thriemer, K., Anstey, N. M., Sugiarto, P., Simpson, J. A., Price, R. N., Douglas, N. M. & Poespoprodjo, J. R., 2 Apr 2019, In : Malaria Journal. 18, p. 1-11 11 p., 111.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
File
Primaquine
Vivax Malaria
Indonesia
Safety
Hemolysis

Short-course primaquine for the radical cure of Plasmodium vivax malaria: a multicentre, randomised, placebo-controlled non-inferiority trial

Taylor, W. R. J., Thriemer, K., von Seidlein, L., Yuentrakul, P., Assawariyathipat, T., Assefa, A., Auburn, S., Chand, K., Chau, N. H., Cheah, P. Y., Dong, L. T., Dhorda, M., Degaga, T. S., Devine, A., Ekawati, L. L., Fahmi, F., Hailu, A., Hasanzai, M. A., Hien, T. T., Khu, H. & 25 others, Ley, B., Lubell, Y., Marfurt, J., Mohammad, H., Moore, K. A., Naddim, M. N., Pasaribu, A. P., Pasaribu, S., Promnarate, C., Rahim, A. G., Sirithiranont, P., Solomon, H., Sudoyo, H., Sutanto, I., Thanh, N. V., Tuyet-Trinh, N. T., Waithira, N., Woyessa, A., Yamin, F. Y., Dondorp, A., Simpson, J. A., Baird, J. K., White, N. J., Day, N. P. & Price, R. N., 14 Sep 2019, In : The Lancet. 394, 10202, p. 929-938 10 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
File
Primaquine
Vivax Malaria
Placebos
Recurrence
Glucosephosphate Dehydrogenase

The efficacy of dihydroartemisinin-piperaquine and artemether-lumefantrine with and without primaquine on Plasmodium vivax recurrence: A systematic review and individual patient data meta-analysis

Commons, R. J., Simpson, J. A., Thriemer, K., Abreha, T., Adam, I., Anstey, N. M., Assefa, A., Awab, G. R., Baird, J. K., Barber, B. E., Chu, C. S., Dahal, P., Daher, A., Davis, T. M. E., Dondorp, A. M., Grigg, M. J., Humphreys, G. S., Hwang, J., Karunajeewa, H., Laman, M. & 18 others, Lidia, K., Moore, B. R., Mueller, I., Nosten, F., Pasaribu, A. P., Pereira, D. B., Phyo, A. P., Poespoprodjo, J. R., Sibley, C. H., Stepniewska, K., Sutanto, I., Thwaites, G., Hien, T. T., White, N. J., William, T., Woodrow, C. J., Guerin, P. J. & Price, R. N., 4 Oct 2019, In : PLoS Medicine. 16, 10, p. 1-21 21 p., e1002928 .

Research output: Contribution to journalArticleResearchpeer-review

Open Access
File
dihydroartemisinin
Primaquine
Plasmodium vivax
Meta-Analysis
Recurrence
4 Downloads (Pure)

The haematological consequences of Plasmodium vivax malaria after chloroquine treatment with and without primaquine: a WorldWide Antimalarial Resistance Network systematic review and individual patient data meta-analysis

Commons, R. J., Simpson, J. A., Thriemer, K., Chu, C. S., Douglas, N. M., Abreha, T., Alemu, S. G., Añez, A., Anstey, N. M., Aseffa, A., Assefa, A., Awab, G. R., Baird, J. K., Barber, B. E., Borghini-Fuhrer, I., D'Alessandro, U., Dahal, P., Daher, A., de Vries, P. J., Erhart, A. & 32 others, Gomes, M. S. M., Grigg, M. J., Hwang, J., Kager, P. A., Ketema, T., Khan, W. A., Lacerda, M. V. G., Leslie, T., Ley, B., Lidia, K., Monteiro, W. M., Pereira, D. B., Phan, G. T., Phyo, A. P., Rowland, M., Saravu, K., Sibley, C. H., Siqueira, A. M., Stepniewska, K., Taylor, W. R. J., Thwaites, G., Tran, B. Q., Hien, T. T., Vieira, J. L. F., Wangchuk, S., Watson, J., William, T., Woodrow, C. J., Nosten, F., Guerin, P. J., White, N. J. & Price, R. N., 1 Aug 2019, In : BMC Medicine. 17, p. 1-13 13 p., 151.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
File
Primaquine
Vivax Malaria
Chloroquine
Antimalarials
Meta-Analysis
2018
2 Downloads (Pure)

Artemether-lumefantrine dosing for malaria treatment in young children and pregnant women: A pharmacokinetic-pharmacodynamic meta-analysis

Kloprogge, F., Workman, L., Borrmann, S., Tékété, M., Lefèvre, G., Hamed, K., Piola, P., Ursing, J., Kofoed, P. E., Mårtensson, A., Ngasala, B., Björkman, A., Ashton, M., Friberg Hietala, S., Aweeka, F., Parikh, S., Mwai, L., Davis, T. M. E., Karunajeewa, H., Salman, S. & 20 others, Checchi, F., Fogg, C., Newton, P. N., Mayxay, M., Deloron, P., Faucher, J. F., Nosten, F., Ashley, E. A., McGready, R., van Vugt, M., Proux, S., Price, R. N., Karbwang, J., Ezzet, F., Bakshi, R., Stepniewska, K., White, N. J., Guerin, P. J., Barnes, K. I. & Tarning, J., 12 Jun 2018, In : PLoS Medicine. 15, 6, p. 1-27 27 p., e1002579.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
File
Malaria
Meta-Analysis
Pregnant Women
Pharmacokinetics
Antimalarials
7 Downloads (Pure)

Artemether-Lumefantrine Versus Chloroquine for the Treatment of Uncomplicated Plasmodium knowlesi Malaria: An Open-Label Randomized Controlled Trial CAN KNOW

Grigg, M., William, T., Barber, B., Rajahram, G. S., Menon, J., Schimann, E., Wilkes, C. S., Patel, K., Chandna, A., Price, R., Yeo, T. & Anstey, N., 15 Jan 2018, In : Clinical Infectious Diseases. 66, 2, p. 229-236 8 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
File
Plasmodium knowlesi
Plasmodium malariae
Chloroquine
Randomized Controlled Trials
Malaysia

Drugs that reduce transmission of falciparum malaria

Price, R. N. & White, N. J., 1 Jun 2018, In : The Lancet Infectious Diseases. 18, 6, p. 585-586 2 p.

Research output: Contribution to journalComment/debateResearchpeer-review

Open Access
Falciparum Malaria
Pharmaceutical Preparations

Erratum for Brunschwig et al., "UCT943, a Next-Generation Plasmodium falciparum PI4K Inhibitor Preclinical Candidate for the Treatment of Malaria": Antimicrob Agents Chemother

Brunschwig, C., Lawrence, N., Taylor, D., Abay, E., Njoroge, M., Basarab, G. S., Le Manach, C., Paquet, T., Gonzalez Cabrera, D., Nchinda, A. T., de Kock, C., Wiesner, L., Denti, P., Waterson, D., Blasco, B., Leroy, D., Witty, M. J., Donini, C., Duffy, J., Wittlin, S. & 28 others, White, K. L., Charman, S. A., Jimenez-Diaz, M. B., Angulo-Barturen, I., Herreros, E., Gamo, F. J., Rochford, R., Mancama, D., Coetzer, T. L., van der Watt, M. E., Reader, J., Birkholtz, L. M., Marsh, K. C., Solapure, S. M., Burke, J. E., McPhail, J. A., Vanaerschot, M., Fidock, D. A., Fish, P. V., Siegl, P., Smith, D. A., Wirjanata, G., Noviyanti, R., Price, R. N., Marfurt, J., Silue, K. D., Street, L. J. & Chibale, K., 27 Nov 2018, In : Antimicrobial Agents and Chemotherapy. 62, 11, p. 1-2 2 p.

Research output: Contribution to journalComment/debateResearch

Open Access
Plasmodium falciparum
Malaria

Expanding the Use of Primaquine for the Radical Cure of Plasmodium vivax

Price, R. N. & Douglas, N. M., 14 Sep 2018, In : Clinical Infectious Diseases. 67, 7, p. 1008-1009 2 p.

Research output: Contribution to journalComment/debateResearchpeer-review

Open Access
Primaquine
Plasmodium vivax
12 Downloads (Pure)

Field evaluation of quantitative point of care diagnostics to measure glucose-6-phosphate dehydrogenase activity

Alam, M. S., Kibria, M. G., Jahan, N., Thriemer, K., Hossain, M. S., Douglas, N. M., Phru, C. S., Khan, W. A., Price, R. N. & Ley, B., 2 Nov 2018, In : PLoS One. 13, 11, p. 1-13 13 p., e0206331.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
File
Point-of-Care Systems
Glucosephosphate Dehydrogenase
glucose-6-phosphate 1-dehydrogenase
Spectrophotometry
spectroscopy
12 Downloads (Pure)

Genomic analysis of a pre-elimination Malaysian Plasmodium vivax population reveals selective pressures and changing transmission dynamics

Auburn, S., Benavente, E. D., Miotto, O., Pearson, R. D., Amato, R., Grigg, M. J., Barber, B. E., William, T., Handayuni, I., Marfurt, J., Trimarsanto, H., Noviyanti, R., Sriprawat, K., Nosten, F., Campino, S., Clark, T. G., Anstey, N. M., Kwiatkowski, D. P. & Price, R. N., 3 Jul 2018, In : Nature Communications. 9, 1, p. 1-12 12 p., 2585.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
File
Plasmodium vivax
Malaysia
elimination
Genes
Chloroquine
3 Downloads (Pure)

Implications of population-level immunity for the emergence of artemisinin-resistant malaria: A mathematical model

Scott, N., Ataide, R., Wilson, D. P., Hellard, M., Price, R. N., Simpson, J. A. & Fowkes, F. J. I., 2 Aug 2018, In : Malaria Journal. 17, 1, p. 1-11 11 p., 279.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
File
Malaria
Immunity
Theoretical Models
Population
Plasmodium falciparum

Investigating the Efficacy of Triple Artemisinin-Based Combination Therapies for Treating Plasmodium falciparum Malaria Patients Using Mathematical Modeling

Dini, S., Zaloumis, S., Cao, P., Price, R. N., Fowkes, F. J. I., van der Pluijm, R. W., McCaw, J. M. & Simpson, J. A., 1 Nov 2018, In : Antimicrobial Agents and Chemotherapy. 62, 11, p. 1-11 11 p., e01068-18.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
Falciparum Malaria
dihydroartemisinin
Mefloquine
Therapeutics
Far East

Loss of complement regulatory proteins on uninfected erythrocytes in vivax and falciparum malaria anemia

Oyong, D. A., Kenangalem, E., Poespoprodjo, J. R., Beeson, J. G., Anstey, N. M., Price, R. N. & Boyle, M. J., 15 Nov 2018, In : JCI Insight. 3, 22, p. 1-11 11 p., e124854.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
Vivax Malaria
Falciparum Malaria
Anemia
Complement System Proteins
Erythrocytes
13 Downloads (Pure)

Low risk of recurrence following artesunate-Sulphadoxine-pyrimethamine plus primaquine for uncomplicated Plasmodium falciparum and Plasmodium vivax infections in the Republic of the Sudan

Hamid, M. M. A., Thriemer, K., Elobied, M. E., Mahgoub, N. S., Boshara, S. A., Elsafi, H. M. H., Gumaa, S. A., Hamid, T., Abdelbagi, H., Basheir, H. M., Marfurt, J., Chen, I., Gosling, R., Price, R. N. & Ley, B., 16 Mar 2018, In : Malaria Journal. 17, 1, p. 1-14 14 p., 117.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
File
Primaquine
Plasmodium vivax
Sudan
Plasmodium falciparum
Malaria
2 Downloads (Pure)

Malaria elimination: Time to target all species

Lover, A. A., Kevin Baird, J., Gosling, R. & Price, R. N., Jul 2018, In : American Journal of Tropical Medicine and Hygiene. 99, 1, p. 17-23 7 p.

Research output: Contribution to journalComment/debateResearchpeer-review

Open Access
File
Malaria
Plasmodium
Plasmodium falciparum
Parasites
Research
3 Downloads (Pure)

Plasmodium falciparum artemisinin resistance monitoring in Sabah, Malaysia: In vivo therapeutic efficacy and kelch13 molecular marker surveillance

Grigg, M. J., William, T., Piera, K. A., Rajahram, G. S., Jelip, J., Aziz, A., Menon, J., Marfurt, J., Price, R. N., Auburn, S., Barber, B. E., Yeo, T. W. & Anstey, N. M., 10 Dec 2018, In : Malaria Journal. 17, 1, p. 1-8 8 p., 463.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
File
Malaysia
Plasmodium falciparum
Parasites
Therapeutics
Malaria

Platelets kill circulating parasites of all major Plasmodium species in human malaria

Kho, S., Barber, B. E., Johar, E., Andries, B., Poespoprodjo, J. R., Kenangalem, E., Piera, K. A., Ehmann, A., Price, R. N., William, T., Woodberry, T., Foote, S., Minigo, G., Yeo, T. W., Grigg, M. J., Anstey, N. M. & McMorran, B. J., 20 Sep 2018, In : Blood. 132, 12, p. 1332-1344 13 p.

Research output: Contribution to journalArticleResearchpeer-review

Plasmodium
Platelets
Malaria
Parasites
Blood Platelets
7 Downloads (Pure)

Quantifying primaquine effectiveness and improving adherence: A round table discussion of the APMEN Vivax Working Group

Thriemer, K., Bobogare, A., Ley, B., Gudo, C. S., Alam, M. S., Anstey, N. M., Ashley, E., Baird, J. K., Gryseels, C., Jambert, E., Lacerda, M., Laihad, F., Marfurt, J., Pasaribu, A. P., Poespoprodjo, J. R., Sutanto, I., Taylor, W. R., Van Den Boogaard, C., Battle, K. E., Dysoley, L. & 78 others, Ghimire, P., Hawley, B., Hwang, J., Khan, W. A., Mudin, R. N. B., Sumiwi, M. E., Ahmed, R., Aktaruzzaman, M. M., Awasthi, K. R., Bardaji, A., Bell, D., Boaz, L., Burdam, F. H., Chandramohan, D., Cheng, Q., Chindawongsa, K., Culpepper, J., Das, S., Deray, R., Desai, M., Domingo, G., Duoquan, W., Duparc, S., Floranita, R., Gerth-Guyette, E., Howes, R. E., Hugo, C., Jagoe, G., Sariwati, E., Jhora, S. T., Jinwei, W., Karunajeewa, H., Kenangalem, E., Lal, B. K., Landuwulang, C., Le Perru, E., Lee, S. E., Makita, L. S., McCarthy, J., Mekuria, A., Mishra, N., Naket, E., Nambanya, S., Nausien, J., Duc, T. N., Thi, T. N., Noviyanti, R., Pfeffer, D., Qi, G., Rahmalia, A., Rogerson, S., Samad, I., Sattabongkot, J., Satyagraha, A., Shanks, D., Sharma, S. N., Sibley, C. H., Sungkar, A., Syafruddin, D., Talukdar, A., Tarning, J., Ter Kuile, F., Thapa, S., Theodora, M., Huy, T. T., Waramin, E., Waramori, G., Woyessa, A., Wongsrichanalai, C., Xa, N. X., Yeom, J. S., Hermawan, L., Devine, A., Nowak, S., Jaya, I., Supargiyono, S., Grietens, K. P. & Price, R. N., 20 Jun 2018, In : Malaria Journal. 17, p. 1-7 7 p., 241.

Research output: Contribution to journalMeeting AbstractResearchpeer-review

Open Access
File
Primaquine
Malaria
Vivax Malaria
Health Promotion
Habits

Spectrophotometry assays to determine G6PD activity from Trinity Biotech and Pointe Scientific G6PD show good correlation

Alam, M. S., Kibria, M. G., Jahan, N., Price, R. N. & Ley, B., 4 Dec 2018, In : BMC Research Notes. 11, 1, p. 1-4 4 p., 855.

Research output: Contribution to journalComment/debateResearchpeer-review

Open Access
Glucosephosphate Dehydrogenase
Spectrophotometry
Assays
Bangladesh
Ireland

The effect of chloroquine dose and primaquine on Plasmodium vivax recurrence: a WorldWide Antimalarial Resistance Network systematic review and individual patient pooled meta-analysis

Commons, R. J., Simpson, J. A., Thriemer, K., Humphreys, G. S., Abreha, T., Alemu, S. G., Añez, A., Anstey, N. M., Awab, G. R., Baird, J. K., Barber, B. E., Borghini-Fuhrer, I., Chu, C. S., D'Alessandro, U., Dahal, P., Daher, A., de Vries, P. J., Erhart, A., Gomes, M. S. M., Gonzalez-Ceron, L. & 34 others, Grigg, M. J., Heidari, A., Hwang, J., Kager, P. A., Ketema, T., Khan, W. A., Lacerda, M. V. G., Leslie, T., Ley, B., Lidia, K., Monteiro, W. M., Nosten, F., Pereira, D. B., Phan, G. T., Phyo, A. P., Rowland, M., Saravu, K., Sibley, C. H., Siqueira, A. M., Stepniewska, K., Sutanto, I., Taylor, W. R. J., Thwaites, G., Tran, B. Q., Tran, H. T., Valecha, N., Vieira, J. L. F., Wangchuk, S., William, T., Woodrow, C. J., Zuluaga-Idarraga, L., Guerin, P. J., White, N. J. & Price, R. N., 1 Sep 2018, In : The Lancet Infectious Diseases. 18, 9, p. 1025-1034 10 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
Primaquine
Plasmodium vivax
Chloroquine
Antimalarials
Meta-Analysis
4 Downloads (Pure)

The ethics of using placebo in randomised controlled trials: A case study of a Plasmodium vivax antirelapse trial

Cheah, P. Y., Steinkamp, N., Von Seidlein, L. & Price, R. N., 6 Mar 2018, In : BMC Medical Ethics. 19, p. 1-5 5 p., 19.

Research output: Contribution to journalComment/debateResearchpeer-review

Open Access
File
Plasmodium vivax
Ethics
Randomized Controlled Trials
moral philosophy
Placebos
7 Downloads (Pure)

The Plasmodium falciparum transcriptome in severe malaria reveals altered expression of genes involved in important processes including surface antigen–encoding var genes

Tonkin-Hill, G. Q., Trianty, L., Noviyanti, R., Nguyen, H. H. T., Sebayang, B. F., Lampah, D. A., Marfurt, J., Cobbold, S. A., Rambhatla, J. S., McConville, M. J., Rogerson, S. J., Brown, G. V., Day, K. P., Price, R. N., Anstey, N. M., Papenfuss, A. T. & Duffy, M. F., 12 Mar 2018, In : PLoS Biology. 16, 3, p. 1-40 40 p., e2004328.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
File
Plasmodium falciparum
Transcriptome
transcriptome
malaria
Malaria
5 Downloads (Pure)

Therapeutic response to dihydroartemisinin-piperaquine for P. falciparum and P. Vivax nine years after its introduction in southern Papua, Indonesia

Poespoprodjo, J. R., Kenangalem, E., Wafom, J., Chandrawati, F., Puspitasari, A. M., Ley, B., Trianty, L., Korten, Z., Surya, A. S., Syafruddin, D., Anstey, N., Marfurt, J., Noviyanti, R. & Price, R., Mar 2018, In : American Journal of Tropical Medicine and Hygiene. 98, 3, p. 677-682 6 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
File
dihydroartemisinin
Indonesia
Plasmodium falciparum
Malaria
Vivax Malaria
1 Downloads (Pure)

Treatment-Seeking Behavior after the Implementation of a Unified Policy of Dihydroartemisinin- Piperaquine for the Treatment of Uncomplicated Malaria in Papua, Indonesia

Devine, A., Kenangalem, E., Burdam, F. H., Anstey, N., Poespoprodjo, J. R., Price, R. & Yeung, S., Feb 2018, In : American Journal of Tropical Medicine and Hygiene. 98, 2, p. 543-550 8 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
File
dihydroartemisinin
Indonesia
Malaria
Antimalarials
Therapeutics
13 Downloads (Pure)

Uct943, a next-generation plasmodium falciparum pi4k inhibitor preclinical candidate for the treatment of malaria

Brunschwig, C., Lawrence, N., Taylor, D., Abay, E., Njoroge, M., Basarab, G. S., Le Manach, C., Paquet, T., Cabrera, D. G., Nchinda, A. T., De Kock, C., Wiesner, L., Denti, P., Waterson, D., Blasco, B., Leroy, D., Witty, M. J., Donini, C., Duffy, J., Wittlin, S. & 28 others, White, K. L., Charman, S. A., Jimenez-Diaz, M. B., Angulo-Barturen, I., Herreros, E., Gamo, F. J., Rochford, R., Mancama, D., Coetzer, T. L., Van der Watt, M. E., Reader, J., Birkholtz, L. M., Marsh, K. C., Solapure, S. M., Burke, J. E., McPhail, J. A., Vanaerschot, M., Fidock, D. A., Fish, P. V., Siegl, P., Smith, D. A., Wirjanata, G., Noviyanti, R., Price, R. N., Marfurt, J., Silue, K. D., Street, L. J. & Chibaleb, K., 1 Sep 2018, In : Antimicrobial Agents and Chemotherapy. 62, 9, p. 1-16 16 p., e00012-18.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
File
1-Phosphatidylinositol 4-Kinase
Plasmodium falciparum
South Africa
Malaria
Plasmodium
2017
3 Downloads (Pure)

A comparison of three quantitative methods to estimate G6PD activity in the chittagong hill tracts, Bangladesh

Ley, B., Alam, M. S., O'Donnell, J. J., Hossain, M. S., Kibria, M. G., Jahan, N., Ali Khan, W., Ley-Thriemer, K., Chatfield, M. D., Price, R. N. & Richards, J. S., 1 Jan 2017, In : PLoS One. 12, 1, p. 1-13 13 p., e0169930.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
File
Bangladesh
glucose-6-phosphate 1-dehydrogenase
Biosensing Techniques
Biosensors
quantitative analysis
4 Downloads (Pure)

Adverse effects of Mefloquine for the treatment of uncomplicated malaria in Thailand: A pooled analysis of 19, 850 individual patients

Lee, S. J., Ter Kuile, F. O., Price, R. N., Luxemburger, C. & Nosten, F., 1 Feb 2017, In : PLoS One. 12, 2, p. 1-16 16 p., 0168780.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
File
Mefloquine
Thailand
malaria
Malaria
adverse effects

Artemether-Lumefantrine

Commons, R., Simpson, J. & Price, R., 2 Oct 2017, Kucers' The use of antibiotics: a clinical review of antibacterial, antifungal, antiparasitic, and antiviral drugs. Grayson, M. L., Cosgrove, S. E., Crowe, S. M., Hope, W., McCarthy, J. S., Mills, J., Mouton, J. W. & Paterson, D. L. (eds.). 7th ed. Boca Raton: CRC Press, Vol. 3. p. 2974-2988 15 p.

Research output: Chapter in Book/Report/Conference proceedingChapterResearchpeer-review

artemether
lumefantrine

Artemisinins

Thriemer, K., Simpson, J. A., McCarthy, J. S. & Price, R. N., 2017, Kucers' the Use of Antibiotics: A Clinical Review of Antibacterial, Antifungal, Antiparasitic, and Antiviral Drugs. Grayson, M. L., Cosgrove, S. E., Crowe, S. M., Hope, W., McCarthy, J. S., Mills, J., Mouton, J. W. & Paterson, D. L. (eds.). 7th ed. CRC Press, Vol. 3. p. 2941-2963 23 p. Part 4:1

Research output: Chapter in Book/Report/Conference proceedingChapterResearchpeer-review

Artemisinins
Antimalarials
Artemisia annua
Sesquiterpenes
Chinese Traditional Medicine

Artesunate

Commons, R., Simpson, J., McCarthy, J. & Price, R., 2 Oct 2017, Kucers' The use of antibiotics: a clinical review of antibacterial, antifungal, antiparasitic, and antiviral drugs. Grayson, M. L., Cosgrove, S. E., Crowe, S. M., Hope, W., McCarthy, J. S., Mills, J., Mouton, J. W. & Paterson, D. L. (eds.). 7th ed. Boca Raton: CRC Press, Vol. 3. p. 2964-2973 10 p.

Research output: Chapter in Book/Report/Conference proceedingChapterResearchpeer-review

artesunate
7 Downloads (Pure)

A tetraoxane-based antimalarial drug candidate that overcomes PfK13-C580Y dependent artemisinin resistance

O'Neill, P. M., Amewu, R. K., Charman, S. A., Sabbani, S., Gnädig, N. F., Straimer, J., Fidock, D. A., Shore, E. R., Roberts, N. L., Wong, M. H. L., Hong, W. D., Pidathala, C., Riley, C., Murphy, B., Aljayyoussi, G., Gamo–Benito, F. J., Sanz, L. M., Rodrigues, J., Cortes, C. G., Herreros, E. & 28 others, Angulo-Barturén, I., Jiménez-Díaz, M. B., Bazaga, S. F., Martínez-Martínez, M. S., Campo, B., Sharma, R., Ryan, E., Shackleford, D. M., Campbell, S., Smith, D. A., Wirjanata, G., Noviyanti, R., Price, R. N., Marfurt, J., Palmer, M. J., Copple, I. M., Mercer, A. E., Ruecker, A., Delves, M. J., Sinden, R. E., Siegl, P., Davies, J., Rochford, R., Kocken, C. H. M., Zeeman, A-M., Nixon, G. L., Biagini, G. A. & Ward, S. A., 24 May 2017, In : Nature Communications. 8, p. 1-12 12 p., 15159.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
File
Tetraoxanes
parasites
Antimalarials
mutations
Pharmacodynamics
10 Downloads (Pure)

Barriers to routine G6PD testing prior to treatment with primaquine

Ley, B., Thriemer, K., Jaswal, J., Poirot, E., Alam, M. S., Phru, C. S., Khan, W. A., Dysoley, L., Qi, G., Kheong, C. C., Shamsudin, U. K., Chen, I., Hwang, J., Gosling, R. & Price, R. N., 10 Aug 2017, In : Malaria Journal. 16, p. 1-10 10 p., 329.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
File
Primaquine
Vivax Malaria
Glucosephosphate Dehydrogenase Deficiency
Glucosephosphate Dehydrogenase
Malaysia
10 Downloads (Pure)

Challenges for achieving safe and effective radical cure of Plasmodium vivax: a round table discussion of the APMEN Vivax Working Group

Thriemer, K., Ley, B., Bobogare, A. B., Dysoley, L., Alam, M. S., Pasaribu, A. P., Sattabongkot-Prachumsri, J. S. P., Jambert, E., Domingo, G. J., Commons, R., Auburn, S., Marfurt, J., Devine, A., Aktaruzzaman, M. M., Sohel, N., Namgay, R. N., Drukpa, T., Sharma, S. N., Sarawati, E., Samad, I. & 47 others, Theodora, M., Nambanya, S., Ounekham, S., Mudin, R. N. B., Da Thakur, G., Makita, L. S., Deray, R., Lee, S. E., Boaz, L., Danansuriya, M. N., Mudiyanselage, S. D., Chinanonwait, N., Kitchakarn, S., Nausien, J., Naket, E., Duc, T. N., Do Manh, H., Hong, Y. S., Cheng, Q., Richards, J. S., Kusriastuti, R., Satyagraha, A. W., Noviyanti, R., Ding, X. C., Khan, W. A., Swe Phru, C., Guoding, Z., Qi, G., Kaneko, A., Miotto, O., Nguitragool, W., Roobsoong, W., Battle, K., Howes, R. E., Roca-Feltrer, A., Duparc, S., Bhowmick, I. P., Kenangalem, E., Bibit, J. A., Barry, A. E., Sintasath, D., Abeyasinghe, R., Sibley, C. H., McCarthy, J., Von Seidlein, L., Baird, J. K. & Price, R. N., 5 Apr 2017, In : Malaria Journal. 16, 141, p. 1-9 9 p., 141.

Research output: Contribution to journalMeeting AbstractResearchpeer-review

Open Access
File
Plasmodium vivax
Glucose-6-Phosphate
Primaquine
Point-of-Care Systems
Malaria