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2019

Atlas of group A streptococcal vaccine candidates compiled using large-scale comparative genomics

Davies, M. R., McIntyre, L., Mutreja, A., Lacey, J. A., Lees, J. A., Towers, R. J., Duchêne, S., Smeesters, P. R., Frost, H. R., Price, D. J., Holden, M. T. G., David, S., Giffard, P. M., Worthing, K. A., Seale, A. C., Berkley, J. A., Harris, S. R., Rivera-Hernandez, T., Berking, O., Cork, A. J. & 18 others, Torres, R. S. L. A., Lithgow, T., Strugnell, R. A., Bergmann, R., Nitsche-Schmitz, P., Chhatwal, G. S., Bentley, S. D., Fraser, J. D., Moreland, N. J., Carapetis, J. R., Steer, A. C., Parkhill, J., Saul, A., Williamson, D. A., Currie, B. J., Tong, S. Y. C., Dougan, G. & Walker, M. J., 1 Jun 2019, In : Nature Genetics. 51, 6, p. 1035-1043 9 p.

Research output: Contribution to journalArticleResearchpeer-review

Streptococcal Vaccines
Atlases
Genomics
Vaccines
Antigens

Author Correction: Atlas of group A streptococcal vaccine candidates compiled using large-scale comparative genomics

Davies, M. R., McIntyre, L., Mutreja, A., Lacey, J. A., Lees, J. A., Towers, R. J., Duchêne, S., Smeesters, P. R., Frost, H. R., Price, D. J., Holden, M. T. G., David, S., Giffard, P. M., Worthing, K. A., Seale, A. C., Berkley, J. A., Harris, S. R., Rivera-Hernandez, T., Berking, O., Cork, A. J. & 18 others, Torres, R. S. L. A., Lithgow, T., Strugnell, R. A., Bergmann, R., Nitsche-Schmitz, P., Chhatwal, G. S., Bentley, S. D., Fraser, J. D., Moreland, N. J., Carapetis, J. R., Steer, A. C., Parkhill, J., Saul, A., Williamson, D. A., Currie, B. J., Tong, S. Y. C., Dougan, G. & Walker, M. J., Aug 2019, In : Nature Genetics. 51, 8, p. 1295-1295 1 p.

Research output: Contribution to journalComment/debateResearchpeer-review

Open Access
Streptococcal Vaccines
Atlases
Genomics
Alleles
Proteins
23 Downloads (Pure)

Concerns for efficacy of a 30-valent M-protein-based Streptococcus pyogenes vaccine in regions with high rates of rheumatic heart disease

Giffard, P., Tong, S. Y. C., Holt, D., Ralph, A. & Currie, B., 3 Jul 2019, In : PLoS Neglected Tropical Diseases. 13, 7, p. 1-20 20 p., e0007511.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
File
Rheumatic Heart Disease
Streptococcus pyogenes
Vaccines
Northern Territory
Proteins

Identification and Discrimination of Chlamydia trachomatis Ocular and Urogenital Strains and Major Phylogenetic Lineages by CtGEM Typing, A Double-Locus Genotyping Method

Holt, D. C., Andersson, P., Buckley, C., Whiley, D. M. & Giffard, P. M., 6 Aug 2019, Methods in Molecular Biology. Humana Press Inc., p. 87-122 36 p. (Methods in Molecular Biology; vol. 2042).

Research output: Chapter in Book/Report/Conference proceedingChapterResearchpeer-review

Chlamydia trachomatis
Genotype
Genome
Phylogeny
Haplotypes
2018

Contaminated fingers: A potential cause of Chlamydia trachomatis-positive urine specimens

Giffard, P. M., Lilliebridge, R. A., Wilson, J., Murray, G., Phillips, S., Tabrizi, S. N., Garland, S. M., Martin, L., Singh, G., Tong, S. Y. C., Holt, D. C. & Andersson, P., 18 Jan 2018, In : Sexually Transmitted Infections. 94, 1, p. 32-36 5 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
Chlamydia trachomatis
Fingers
Urine
Urine Specimen Collection
Sexually Transmitted Diseases
6 Downloads (Pure)

CtGEM typing: Discrimination of Chlamydia trachomatis ocular and urogenital strains and major evolutionary lineages by high resolution melting analysis of two amplified DNA fragments

Giffard, P. M., Andersson, P., Wilson, J., Buckley, C., Lilliebridge, R., Harris, T. M., Kleinecke, M., O’Grady, K. A. F., Huston, W. M., Lambert, S. B., Whiley, D. M. & Holt, D. C., 1 Apr 2018, In : PLoS One. 13, 4, p. 1-18 18 p., e0195454.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
File
Chlamydia trachomatis
melting
Freezing
Melting
eyes
10 Downloads (Pure)

Global scale dissemination of ST93: A divergent staphylococcus aureus epidemic lineage that has recently emerged from remote northern Australia

van Hal, S. J., Steinig, E. J., Andersson, P., Holden, M. T. G., Harris, S. R., Nimmo, G. R., Williamson, D. A., Heffernan, H., Ritchie, S. R., Kearns, A. M., Ellington, M. J., Dickson, E., de Lencastre, H., Coombs, G. W., Bentley, S. D., Parkhill, J., Holt, D. C., Giffard, P. M. & Tong, S. Y. C., 9 Jul 2018, In : Frontiers in Microbiology. 9, July, p. 1-11 11 p., 1453.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
File
Staphylococcus aureus
Methicillin-Resistant Staphylococcus aureus
Population
Genome
New Zealand

Investigation of trimethoprim/sulfamethoxazole resistance in an emerging sequence type 5 methicillin-resistant Staphylococcus aureus clone reveals discrepant resistance reporting

Harris, T. M., Bowen, A. C., Holt, D. C., Sarovich, D. S., Stevens, K., Currie, B. J., Howden, B. P., Carapetis, J. R., Giffard, P. M. & Tong, S. Y. C., Sep 2018, In : Clinical Microbiology and Infection. 24, 9, p. 1027-1029 3 p.

Research output: Contribution to journalLetterResearchpeer-review

Open Access
File
Trimethoprim Resistance
Sulfamethoxazole Drug Combination Trimethoprim
Methicillin-Resistant Staphylococcus aureus
Clone Cells
2017
1 Downloads (Pure)

Comprehensive global genome dynamics of Chlamydia trachomatis show ancient diversification followed by contemporary mixing and recent lineage expansion

Hadfield, J., Harris, S. R., Seth-Smith, H. M. B., Parmar, S., Andersson, P., Giffard, P. M., Schachter, J., Moncada, J., Ellison, L., Vaulet, M. L. G., Fermepin, M. R., Radebe, F., Mendoza, S., Ouburg, S., Morré, S. A., Sachse, K., Puolakkainen, M., Korhonen, S. J., Sonnex, C., Wiggins, R. & 18 others, Jalal, H., Brunelli, T., Casprini, P., Pitt, R., Ison, C., Savicheva, A., Shipitsyna, E., Hadad, R., Kari, L., Burton, M. J., Mabey, D., Solomon, A. W., Lewis, D., Marsh, P., Unemo, M., Clarke, I. N., Parkhill, J. & Thomson, N. R., Jul 2017, In : Genome Research. 27, 7, p. 1220-1229 10 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
File
Chlamydia trachomatis
History
Genome
Ecotype
Blindness
2 Downloads (Pure)

Primary health clinic toilet/bathroom surface swab sampling can indicate community profile of sexually transmitted infections

Giffard, P. M., Su, J. Y., Andersson, P. & Holt, D. C., 22 Jun 2017, In : PEERJ. 2017, 5, p. 1-11 11 p., e3487.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
File
Toilet Facilities
sexually transmitted diseases
Sexually Transmitted Diseases
Nucleic Acids
Health

What does Chlamydia trachomatis detection in a urogenital specimen from a young child mean?

Giffard, P., Singh, G. & Garland, S. M., 4 Jun 2017, In : Sexually Transmitted Infections. 93, 4, p. 236-237 2 p.

Research output: Contribution to journalEditorialResearch

Chlamydia trachomatis
2016
11 Downloads (Pure)

Chlamydia trachomatis from Australian Aboriginal people with trachoma are polyphyletic composed of multiple distinctive lineages

Andersson, P., Harris, S., Smith, H., Hadfield, J., O'Neill, C., Cutcliffe, LT., Douglas, F., Asche, LV., Seth-Smith, H. M. B., Hadfield, J., Colette E, ON., Lesley T, C., Fiona P, D., Asche, LV., Mathews, J., Hutton, S., Sarovich, D., Tong, S., Clarke, I., Thomson, N. & 1 others, Giffard, P., 2016, In : Nature Communications. 25, 7, p. 1-11 11 p., 10688.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
File
Trachoma
genome
Chlamydia trachomatis
tropism
Genes
1 Downloads (Pure)

Chlamydia trachomatis genotypes in a cross-sectional study of urogenital samples from remote Northern and central Australia

Giffard, P., Brenner, N., Tabrizi, S., Garland, S., Holt, D., Andersson, P., Gorie, R., Tong, S., Karimi, M., Boylan, P., Ryder, N., Johns, T. & Singh, G., 1 Jan 2016, In : BMJ Open. 6, p. 1-7 7 p., e009624.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
File
Chlamydia trachomatis
Cross-Sectional Studies
Genotype
Northern Territory
Trachoma

Differing epidemiology of two major healthcare-associated meticillin-resistant Staphylococcus aureus clones

Jeremiah, C., Kandiah, J. P., Spelman, D., Giffard, P., Coombs, G., Jenney, A. & Tong, S., 2016, In : Journal of Hospital Infection. 92, 2, p. 183-190 8 p.

Research output: Contribution to journalArticleResearchpeer-review

Methicillin
Staphylococcus aureus
Epidemiology
Clone Cells
Delivery of Health Care
2 Downloads (Pure)

Molecular epidemiology of methicillin-resistant Staphylococcus aureus isolated from Australian veterinarians

Groves, MD., Crouch, B., Coombs, G., Jordan, D., Pang, S., Barton, Giffard, P., Abraham, S. & Trott, 2016, In : PLoS One. 11, 1, p. 1-12 12 p., e0146034.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
File
molecular epidemiology
Methicillin
Molecular Epidemiology
Veterinarians
Methicillin-Resistant Staphylococcus aureus

Whole genome sequencing reveals extensive community-level transmission of group A Streptococcus in remote communities

Bowen, A., Harris, T., Holt, D., Giffard, P., Carapetis, J., Campbell, P. T. H., McVernon, J. & Tong, S., Jul 2016, In : Epidemiology and Infection. 144, 9, p. 1991-1998 8 p.

Research output: Contribution to journalArticleResearchpeer-review

Impetigo
Streptococcus
Genome
Streptococcus pyogenes
Single Nucleotide Polymorphism
2 Downloads (Pure)

Whole genome sequencing to investigate a putative outbreak of the virulent community-associated methicillin-resistant Staphylococcus aureus ST93 clone in a remote Indigenous community

Meumann, E. M., Andersson, P., Yeaman, F., Oldfield, S., Lilliebridge, R. A., Bentley, S. D., Krause, V., Beaman, M., Currie, B., Holt, D., Giffard, P. & Tong, S., 2016, In : Microbial Genomics. 2, 12, p. 1-7 7 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
File
Methicillin-Resistant Staphylococcus aureus
Disease Outbreaks
Clone Cells
Genome
Staphylococcus aureus