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2020

Comparative genomic analysis identifies X-factor (haemin)-independent Haemophilus haemolyticus: a formal re-classification of 'Haemophilus intermedius'

Harris, T. M., Price, E. P., Sarovich, D. S., Nørskov-Lauritsen, N., Beissbarth, J., Chang, A. B. & Smith-Vaughan, H. C., 1 Jan 2020, In : Microbial Genomics. 6, 1, p. 1-13 13 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
File
Haemophilus
Hemin
Haemophilus parainfluenzae
Haemophilus influenzae
Genome
2019

A comparison of flocked nylon swabs and non-flocked rayon swabs for detection of respiratory bacteria in nasopharyngeal carriage in Australian Indigenous children

Wigger, C., Morris, P. S., Stevens, M., Smith-Vaughan, H., Hare, K., Beissbarth, J. & Leach, A. J., 1 Feb 2019, In : Journal of Microbiological Methods. 157, p. 47-49 3 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
File
Nylons
Bacteria
Haemophilus influenzae
Streptococcus pneumoniae
Moraxella (Branhamella) catarrhalis

Antimicrobial susceptibility and impact of macrolide antibiotics on Moraxella catarrhalis in the upper and lower airways of children with chronic endobronchial suppuration

Hare, K., Seib, K., Chang, A., Harris, T., Spargo, J. & Smith-Vaughan, H., 1 Aug 2019, In : Journal of Medical Microbiology. 68, 8, p. 1140-1147 8 p.

Research output: Contribution to journalArticleResearchpeer-review

Moraxella (Branhamella) catarrhalis
Suppuration
Macrolides
Anti-Bacterial Agents
Erythromycin

Do combined upper airway cultures identify lower airway infections in children with chronic cough?

Hare, K., Chang, A., Smith-Vaughan, H., Bauert, P., Spain, B., Beissbarth, J. & Grimwood, K., Jun 2019, In : Pediatric Pulmonology. 54, 6, p. 907-913 7 p.

Research output: Contribution to journalArticleResearchpeer-review

Cough
Confidence Intervals
Infection
Suppuration
Moraxella (Branhamella) catarrhalis

Efficacy of oral amoxicillin–clavulanate or azithromycin for non-severe respiratory exacerbations in children with bronchiectasis (BEST-1): a multicentre, three-arm, double-blind, randomised placebo-controlled trial

Goyal, V., Grimwood, K., Ware, R. S., Byrnes, C. A., Morris, P. S., Masters, I. B., McCallum, G. B., Binks, M. J., Smith-Vaughan, H., O'Grady, K. A. F., Champion, A., Buntain, H. M., Schultz, A., Chatfield, M., Torzillo, P. J. & Chang, A. B., 1 Sep 2019, In : The Lancet Respiratory Medicine. 7, 9, p. 791-801 11 p.

Research output: Contribution to journalArticleResearchpeer-review

Azithromycin
Bronchiectasis
Randomized Controlled Trials
Placebos
New Zealand
3 Downloads (Pure)

HOspitalised Pneumonia Extended (HOPE) Study to reduce the long-term effects of childhood pneumonia: protocol for a multicentre, double-blind, parallel, superiority randomised controlled trial

Chang, A., Fong, S. M., Yeo, T., Ware, R. S., Mccallum, G., Nathan, A., Ooi, M. H., de Bruyne, J., Byrnes, C. A., LEE, B., Nachiappan, N., Saari, N., Torzillo, P., Smith-Vaughan, H., Morris, P., Upham, J. W. & Grimwood, K., 24 Apr 2019, In : BMJ Open. 9, 4, p. 1-9 9 p., e026411.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
File
Bronchiectasis
Malaysia
Pneumonia
Amoxicillin
Respiratory Signs and Symptoms

Method for culturing Candidatus Ornithobacterium hominis

Lawrence, K. A., Harris, T. M., Salter, S. J., Hall, R. W., Smith-Vaughan, H. C., Chang, A. B. & Marsh, R. L., Apr 2019, In : Journal of Microbiological Methods. 159, April, p. 157-160 4 p.

Research output: Contribution to journalArticleResearchpeer-review

Ornithobacterium
Microbiota
Bacteria
3 Downloads (Pure)

Molecular Signatures of Non-typeable Haemophilus influenzae Lung Adaptation in Pediatric Chronic Lung Disease

Aziz, A., Sarovich, D. S., Nosworthy, E., Beissbarth, J., Chang, A. B., Smith-Vaughan, H., Price, E. P. & Harris, T. M., 16 Jul 2019, In : Frontiers in Microbiology. 10, July, p. 1-13 13 p., 1622.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
File
Haemophilus influenzae
Lung Diseases
Chronic Disease
Pediatrics
Lung

Multiple Respiratory Microbiota Profiles Are Associated With Lower Airway Inflammation in Children With Protracted Bacterial Bronchitis

Marsh, R. L., Smith-Vaughan, H. C., Chen, A. C. H., Marchant, J. M., Yerkovich, S. T., Gibson, P. G., Pizzutto, S. J., Hodge, S., Upham, J. W. & Chang, A. B., Apr 2019, In : Chest. 155, 4, p. 778-786 9 p.

Research output: Contribution to journalArticleResearchpeer-review

Bronchitis
Microbiota
Dimercaprol
Inflammation
Biomass

Povidone-iodine ear wash and oral cotrimoxazole for chronic suppurative otitis media in Australian aboriginal children: Study protocol for factorial design randomised controlled trial

Wigger, C., Leach, A. J., Beissbarth, J., Oguoma, V., Lennox, R., Nelson, S., Patel, H., Chatfield, M., Currie, K., Coates, H., Edwards, K., Smith-Vaughan, H., Hare, K., Torzillo, P., Tong, S. & Morris, P., 27 Jul 2019, In : BMC Pharmacology and Toxicology. 20, p. 1-6 6 p., 46.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
File
Suppurative Otitis Media
Povidone-Iodine
Sulfamethoxazole Drug Combination Trimethoprim
Ear
Randomized Controlled Trials

Recent advances in understanding the natural history of the otitis media microbiome and its response to environmental pressures

Marsh, R. L., Aho, C., Beissbarth, J., Bialasiewicz, S., Binks, M., Cervin, A., Kirkham, L. A. S., Lemon, K. P., Slack, M. P. E. & Smith-Vaughan, H. C., 18 Dec 2019, In : International Journal of Pediatric Otorhinolaryngology. p. 1-15 15 p., 109836.

Research output: Contribution to journalArticleResearchpeer-review

Microbiota
Otitis Media
Middle Ear
Pressure
National Library of Medicine (U.S.)
Open Access
Respiratory Syncytial Viruses
infant
Population
community
Viruses
Haemophilus influenzae
Conjugate Vaccines
Population Groups
Northern Territory
Pediatrics
2018

Bacteria and viruses in the nasopharynx immediately prior to onset of acute lower respiratory infections in Indigenous Australian children

Smith-Vaughan, H., Binks, M., Beissbarth, J., Chang, A., Mccallum, G., Mackay, I. M., Morris, P., Marsh, R., Torzillo, P. J., Wurzel, D. F., Grimwood, K., Nosworthy, E., Gaydon, J. E., Leach, A., Machunter, B., Chatfield, M., Sloots, T. P. & Cheng, A. C., 2018, In : European Journal of Clinical Microbiology and Infectious Diseases. 37, 9, p. 1785–1794 10 p.

Research output: Contribution to journalArticleResearchpeer-review

Nasopharynx
Respiratory Tract Infections
Viruses
Bacteria
Human Adenoviruses

Defining lower airway bacterial infection in children with chronic endobronchial disorders

Hare, K., Pizzutto, S., Chang, A., Smith-Vaughan, H., Mccallum, G., Beissbarth, J., Versteegh, L. & Grimwood, K., Feb 2018, In : Pediatric Pulmonology. 53, 2, p. 224-232 9 p.

Research output: Contribution to journalArticleResearchpeer-review

Bacterial Load
Bacterial Infections
Bronchoalveolar Lavage
Cell Count
Neutrophils
7 Downloads (Pure)

Evaluation of different infant vaccination schedules incorporating pneumococcal vaccination (The Vietnam Pneumococcal Project): protocol of a randomised controlled trial

Temple, E., Toan, N. T., Uyen, D. Y., Balloch, A., Bright, K., Cheung, Y. B., Licciardi, P., Nguyen, C. D., Phuong, N. T. M., Satzke, C., Smith-Vaughan, H., Vu, T. Q. H., Huu, T. N. & Mulholland, E. K., 8 Jun 2018, In : BMJ Open. 8, 6, p. 1-11 11 p., e019795.

Research output: Contribution to journalComment/debateResearchpeer-review

Open Access
File
Conjugate Vaccines
Pneumococcal Vaccines
Vietnam
Appointments and Schedules
Vaccination
9 Downloads (Pure)

How low can we go? The implications of low bacterial load in respiratory microbiota studies

Marsh, R., Nelson, M. T., Pope, C., Leach, A., Hoffman, L., Chang, A. & Smith-Vaughan, H., 5 Jul 2018, In : Pneumonia. 10, p. 1-9 9 p., 7.

Research output: Contribution to journalReview articleResearchpeer-review

Open Access
File
Bacterial Load
Microbiota
Bacteria
Lung
DNA
2 Downloads (Pure)
Open Access
File
Haemophilus influenzae
Polymerase Chain Reaction
Pharynx
Nose
Haemophilus

The clinical, immunological and microbiological impact of the 10-valent pneumococcal-Protein D conjugate vaccine in children with recurrent protracted bacterial bronchitis, chronic suppurative lung disease and bronchiectasis: a multi-centre, double-blind, randomised controlled trial

O'Grady, K. F., Chang, A., Cripps, A., Mulholland, E. K., Smith-Vaughan, H., Wood, N., Danchin, M., Thornton, R., Wilson, A., Torzillo, P. J., Morris, P., Richmond, P., Rablin, S., Arnold, D., Connor, A., Goyal, V., Stoney, T., Perrett, K. & Grimwood, K., 2 Nov 2018, In : Human Vaccines and Immunotherapeutics. 14, 11, p. 2768-2779 12 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
Conjugate Vaccines
Bronchiectasis
Chronic Bronchitis
Lung Diseases
Randomized Controlled Trials
2017

Culture of non-typeable Haemophilus influenzae from the nasopharynx: Not all media are equal

Harris, T. M., Rumaseb, A., Beissbarth, J., Barzi, F., Leach, A. J. & Smith-Vaughan, H. C., Jun 2017, In : Journal of Microbiological Methods. 137, p. 3-5 3 p.

Research output: Contribution to journalComment/debateResearchpeer-review

Nasopharynx
Haemophilus influenzae
Agar
Bacitracin
Clindamycin

Propensity of pneumococcal carriage serotypes to infect the lower airways of children with chronic endobronchial infections

Hare, K. M., Smith-Vaughan, H. C., Chang, A. B., Pizzutto, S., Petsky, H. L., McCallum, G. B. & Leach, A. J., 1 Feb 2017, In : Vaccine. 35, 5, p. 747-756 10 p.

Research output: Contribution to journalArticleResearchpeer-review

serotypes
Infection
infection
Bronchoalveolar Lavage
odds ratio

Simultaneous identification of Haemophilus influenzae and Haemophilus haemolyticus using real-time PCR

Price, E. P., Harris, T. M., Spargo, J., Nosworthy, E., Beissbarth, J., Chang, A. B., Smith-Vaughan, H. C. & Sarovich, D. S., Jun 2017, In : Future Microbiology. 12, 7, p. 585-593 9 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
Haemophilus
Haemophilus influenzae
Real-Time Polymerase Chain Reaction
Polymerase Chain Reaction
Fucose

Streptococcus pneumoniae and chronic endobronchial infections in childhood

Hare, K., Leach, A., Smith-Vaughan, H., Chang, A. & Grimwood, K., Dec 2017, In : Pediatric Pulmonology. 52, 12, p. 1532-1545 14 p.

Research output: Contribution to journalArticleResearchpeer-review

Streptococcus pneumoniae
Bronchiectasis
Lung Diseases
Infection
Bronchitis
2016
Open Access
Northern Territory
Fetal Blood
Vitamin D
Respiratory Tract Infections
Mothers
Open Access
Northern Territory
Conjugate Vaccines
Otitis Media
Middle Ear
Microbiology
3 Downloads (Pure)

Geographic consistency in dominant, non-typeable Haemophilus influenzae genotypes colonising four distinct Australian paediatric groups: a cohort study

Smith-Vaughan, H., Beissbarth, J., Bowman, J., Hare, K., PRICE, E., Pickering, J., Lehmann, D., Chang, A., Morris, P., Marsh, R. & Leach, A., 2016, In : Pneumonia. 8, 13, p. 1-6 6 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
File
Haemophilus influenzae
Cohort Studies
Genotype
Pediatrics
Ribotyping

Limited impact of neonatal or early infant schedules of 7-valent pneumococcal conjugate vaccination on nasopharyngeal carriage of Streptococcus pneumoniae in Papua New Guinean children: A randomized controlled trial

Aho, C., Michael, A., Yoannes, M., Greenhill, A., Jacoby, P., Reeder, J. R., Pomat, W., Saleu, G., Namuigi, P., Phuanukoonnon, S., Smith-Vaughan, H., Leach, A. J., Richmond, P. & Lehmann, D., 1 Dec 2016, In : Vaccine Reports. 6, p. 36-43 8 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
File
Pneumococcal Vaccines
Conjugate Vaccines
Streptococcus pneumoniae
Appointments and Schedules
Vaccination
16 Downloads (Pure)

Protracted Bacterial Bronchitis in Children: Natural History and Risk Factors for Bronchiectasis

Wurzel, D. F., Marchant, J. M., Yerkovich, S. T., Upham, J. W., Petsky, H. L., Smith-Vaughan, H., Masters, B., Buntain, H. & Chang, A. B., Nov 2016, In : Chest. 150, 5, p. 1101-1108 8 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
File
Bronchiectasis
Bronchitis
Natural History
Human Influenza
Dimercaprol

The microbiota in bronchoalveolar lavage from young children with chronic lung disease includes taxa present in both the oropharynx and nasopharynx

Marsh, R. L., Kaestli, M., Chang, A. B., Binks, M. J., Pope, C. E., Hoffman, L. R. & Smith-Vaughan, H. C., 2016, In : Microbiome. 4, 37, p. 1-18 18 p., 37.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
Oropharynx
Nasopharynx
Microbiota
Bronchoalveolar Lavage
Lung Diseases