A comparison of the potent in vitro antitumor activity of triphenyltin benzoates with that of related tin compounds

Carolyn J. Tranter, Susan J. Berners Price, Janelle Cutts, Peter G. Parsons, Gavin Rintoul, David J. Young

Research output: Contribution to journalArticle

Abstract

A variety of structurally diverse triphenyltin esters exhibit almost identical in vitro antitumor activity to the potent triphenyltin benzoates and greater activity than cisplatin. This activity is independent of the structure of the ester moiety and comparable to triphenyltin hydroxide, suggesting hydrolysis to a common, cytotoxic tin intermediate.

Original languageEnglish
Pages (from-to)165-167
Number of pages3
JournalMain Group Chemistry
Volume1
Issue number1
DOIs
Publication statusPublished - 1995
Externally publishedYes

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