A mortality review of adult inpatients with tuberculosis in Mendi, Papua New Guinea

K. Vakadem, A. Anota, M. Sa'avu, C. Ramoni, L. Comrie-Thomson, M. Gale, Robert Commons

Research output: Contribution to journalArticleResearchpeer-review

Abstract

Setting: Mendi Provincial Hospital, Southern Highlands Province, Papua New Guinea (PNG).

Background: PNG is a high burden country for tuberculosis (TB) and TB-human immunodeficiency virus (HIV). TB is the second most common cause of death in PNG.

Objective: To identify the number of adult inpatients with TB who died between 1 January 2015 and 30 August 2017; describe these patients’ characteristics and identify contributing factors that could be modified.

Design: This was a retrospective case series review.

Results: Among 905 inpatients with TB during the study period, there were 90 deaths. The patients who died were older than those who survived (median age 40 years vs. 32 years, P = 0.011). The majority of patients who died lived less than 3 hours from the hospital (71%),
were diagnosed after admission (79%) and were clinically diagnosed (77%). HIV status was not known in 50% of the deaths. Of patients with a known status, 27% (12/45) were HIV-positive. The median symptom duration prior to presentation was 28 days, with females presenting later than males (84 vs. 28 days, P = 0.008).

Conclusion: This study highlights areas where community and hospital-based management of TB could be improved to potentially reduce TB mortality, including earlier detection and treatment, improved bacteriological diagnosis and increased HIV testing
Original languageEnglish
Pages (from-to)S62-S67
Number of pages6
JournalPublic Health Action
Volume9
Issue numberSupplement 1
DOIs
Publication statusPublished - 21 Sep 2019

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Papua New Guinea
Inpatients
Tuberculosis
Mortality
HIV
Community Hospital
Cause of Death

Cite this

Vakadem, K., Anota, A., Sa'avu, M., Ramoni, C., Comrie-Thomson, L., Gale, M., & Commons, R. (2019). A mortality review of adult inpatients with tuberculosis in Mendi, Papua New Guinea. Public Health Action, 9(Supplement 1), S62-S67. https://doi.org/10.5588/pha.18.0068
Vakadem, K. ; Anota, A. ; Sa'avu, M. ; Ramoni, C. ; Comrie-Thomson, L. ; Gale, M. ; Commons, Robert. / A mortality review of adult inpatients with tuberculosis in Mendi, Papua New Guinea. In: Public Health Action. 2019 ; Vol. 9, No. Supplement 1. pp. S62-S67.
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Vakadem, K, Anota, A, Sa'avu, M, Ramoni, C, Comrie-Thomson, L, Gale, M & Commons, R 2019, 'A mortality review of adult inpatients with tuberculosis in Mendi, Papua New Guinea' Public Health Action, vol. 9, no. Supplement 1, pp. S62-S67. https://doi.org/10.5588/pha.18.0068

A mortality review of adult inpatients with tuberculosis in Mendi, Papua New Guinea. / Vakadem, K.; Anota, A.; Sa'avu, M.; Ramoni, C.; Comrie-Thomson, L.; Gale, M.; Commons, Robert.

In: Public Health Action, Vol. 9, No. Supplement 1, 21.09.2019, p. S62-S67.

Research output: Contribution to journalArticleResearchpeer-review

TY - JOUR

T1 - A mortality review of adult inpatients with tuberculosis in Mendi, Papua New Guinea

AU - Vakadem, K.

AU - Anota, A.

AU - Sa'avu, M.

AU - Ramoni, C.

AU - Comrie-Thomson, L.

AU - Gale, M.

AU - Commons, Robert

PY - 2019/9/21

Y1 - 2019/9/21

N2 - Setting: Mendi Provincial Hospital, Southern Highlands Province, Papua New Guinea (PNG).Background: PNG is a high burden country for tuberculosis (TB) and TB-human immunodeficiency virus (HIV). TB is the second most common cause of death in PNG.Objective: To identify the number of adult inpatients with TB who died between 1 January 2015 and 30 August 2017; describe these patients’ characteristics and identify contributing factors that could be modified.Design: This was a retrospective case series review.Results: Among 905 inpatients with TB during the study period, there were 90 deaths. The patients who died were older than those who survived (median age 40 years vs. 32 years, P = 0.011). The majority of patients who died lived less than 3 hours from the hospital (71%),were diagnosed after admission (79%) and were clinically diagnosed (77%). HIV status was not known in 50% of the deaths. Of patients with a known status, 27% (12/45) were HIV-positive. The median symptom duration prior to presentation was 28 days, with females presenting later than males (84 vs. 28 days, P = 0.008).Conclusion: This study highlights areas where community and hospital-based management of TB could be improved to potentially reduce TB mortality, including earlier detection and treatment, improved bacteriological diagnosis and increased HIV testing

AB - Setting: Mendi Provincial Hospital, Southern Highlands Province, Papua New Guinea (PNG).Background: PNG is a high burden country for tuberculosis (TB) and TB-human immunodeficiency virus (HIV). TB is the second most common cause of death in PNG.Objective: To identify the number of adult inpatients with TB who died between 1 January 2015 and 30 August 2017; describe these patients’ characteristics and identify contributing factors that could be modified.Design: This was a retrospective case series review.Results: Among 905 inpatients with TB during the study period, there were 90 deaths. The patients who died were older than those who survived (median age 40 years vs. 32 years, P = 0.011). The majority of patients who died lived less than 3 hours from the hospital (71%),were diagnosed after admission (79%) and were clinically diagnosed (77%). HIV status was not known in 50% of the deaths. Of patients with a known status, 27% (12/45) were HIV-positive. The median symptom duration prior to presentation was 28 days, with females presenting later than males (84 vs. 28 days, P = 0.008).Conclusion: This study highlights areas where community and hospital-based management of TB could be improved to potentially reduce TB mortality, including earlier detection and treatment, improved bacteriological diagnosis and increased HIV testing

KW - death audit

KW - preventable deaths

KW - risk factors

U2 - 10.5588/pha.18.0068

DO - 10.5588/pha.18.0068

M3 - Article

VL - 9

SP - S62-S67

JO - Public Health Action

JF - Public Health Action

SN - 2220-8372

IS - Supplement 1

ER -

Vakadem K, Anota A, Sa'avu M, Ramoni C, Comrie-Thomson L, Gale M et al. A mortality review of adult inpatients with tuberculosis in Mendi, Papua New Guinea. Public Health Action. 2019 Sep 21;9(Supplement 1):S62-S67. https://doi.org/10.5588/pha.18.0068