A mortality review of adult inpatients with tuberculosis in Mendi, Papua New Guinea

K. Vakadem, A. Anota, M. Sa'avu, C. Ramoni, L. Comrie-Thomson, M. Gale, Robert Commons

    Research output: Contribution to journalArticleResearchpeer-review

    Abstract

    Setting: Mendi Provincial Hospital, Southern Highlands Province, Papua New Guinea (PNG).

    Background: PNG is a high burden country for tuberculosis (TB) and TB-human immunodeficiency virus (HIV). TB is the second most common cause of death in PNG.

    Objective: To identify the number of adult inpatients with TB who died between 1 January 2015 and 30 August 2017; describe these patients’ characteristics and identify contributing factors that could be modified.

    Design: This was a retrospective case series review.

    Results: Among 905 inpatients with TB during the study period, there were 90 deaths. The patients who died were older than those who survived (median age 40 years vs. 32 years, P = 0.011). The majority of patients who died lived less than 3 hours from the hospital (71%),
    were diagnosed after admission (79%) and were clinically diagnosed (77%). HIV status was not known in 50% of the deaths. Of patients with a known status, 27% (12/45) were HIV-positive. The median symptom duration prior to presentation was 28 days, with females presenting later than males (84 vs. 28 days, P = 0.008).

    Conclusion: This study highlights areas where community and hospital-based management of TB could be improved to potentially reduce TB mortality, including earlier detection and treatment, improved bacteriological diagnosis and increased HIV testing
    Original languageEnglish
    Pages (from-to)S62-S67
    Number of pages6
    JournalPublic Health Action
    Volume9
    Issue numberSupplement 1
    DOIs
    Publication statusPublished - 21 Sep 2019

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    Papua New Guinea
    Inpatients
    Tuberculosis
    Mortality
    HIV
    Community Hospital
    Cause of Death

    Cite this

    Vakadem, K., Anota, A., Sa'avu, M., Ramoni, C., Comrie-Thomson, L., Gale, M., & Commons, R. (2019). A mortality review of adult inpatients with tuberculosis in Mendi, Papua New Guinea. Public Health Action, 9(Supplement 1), S62-S67. https://doi.org/10.5588/pha.18.0068
    Vakadem, K. ; Anota, A. ; Sa'avu, M. ; Ramoni, C. ; Comrie-Thomson, L. ; Gale, M. ; Commons, Robert. / A mortality review of adult inpatients with tuberculosis in Mendi, Papua New Guinea. In: Public Health Action. 2019 ; Vol. 9, No. Supplement 1. pp. S62-S67.
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    abstract = "Setting: Mendi Provincial Hospital, Southern Highlands Province, Papua New Guinea (PNG).Background: PNG is a high burden country for tuberculosis (TB) and TB-human immunodeficiency virus (HIV). TB is the second most common cause of death in PNG.Objective: To identify the number of adult inpatients with TB who died between 1 January 2015 and 30 August 2017; describe these patients’ characteristics and identify contributing factors that could be modified.Design: This was a retrospective case series review.Results: Among 905 inpatients with TB during the study period, there were 90 deaths. The patients who died were older than those who survived (median age 40 years vs. 32 years, P = 0.011). The majority of patients who died lived less than 3 hours from the hospital (71{\%}),were diagnosed after admission (79{\%}) and were clinically diagnosed (77{\%}). HIV status was not known in 50{\%} of the deaths. Of patients with a known status, 27{\%} (12/45) were HIV-positive. The median symptom duration prior to presentation was 28 days, with females presenting later than males (84 vs. 28 days, P = 0.008).Conclusion: This study highlights areas where community and hospital-based management of TB could be improved to potentially reduce TB mortality, including earlier detection and treatment, improved bacteriological diagnosis and increased HIV testing",
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    Vakadem, K, Anota, A, Sa'avu, M, Ramoni, C, Comrie-Thomson, L, Gale, M & Commons, R 2019, 'A mortality review of adult inpatients with tuberculosis in Mendi, Papua New Guinea', Public Health Action, vol. 9, no. Supplement 1, pp. S62-S67. https://doi.org/10.5588/pha.18.0068

    A mortality review of adult inpatients with tuberculosis in Mendi, Papua New Guinea. / Vakadem, K.; Anota, A.; Sa'avu, M.; Ramoni, C.; Comrie-Thomson, L.; Gale, M.; Commons, Robert.

    In: Public Health Action, Vol. 9, No. Supplement 1, 21.09.2019, p. S62-S67.

    Research output: Contribution to journalArticleResearchpeer-review

    TY - JOUR

    T1 - A mortality review of adult inpatients with tuberculosis in Mendi, Papua New Guinea

    AU - Vakadem, K.

    AU - Anota, A.

    AU - Sa'avu, M.

    AU - Ramoni, C.

    AU - Comrie-Thomson, L.

    AU - Gale, M.

    AU - Commons, Robert

    PY - 2019/9/21

    Y1 - 2019/9/21

    N2 - Setting: Mendi Provincial Hospital, Southern Highlands Province, Papua New Guinea (PNG).Background: PNG is a high burden country for tuberculosis (TB) and TB-human immunodeficiency virus (HIV). TB is the second most common cause of death in PNG.Objective: To identify the number of adult inpatients with TB who died between 1 January 2015 and 30 August 2017; describe these patients’ characteristics and identify contributing factors that could be modified.Design: This was a retrospective case series review.Results: Among 905 inpatients with TB during the study period, there were 90 deaths. The patients who died were older than those who survived (median age 40 years vs. 32 years, P = 0.011). The majority of patients who died lived less than 3 hours from the hospital (71%),were diagnosed after admission (79%) and were clinically diagnosed (77%). HIV status was not known in 50% of the deaths. Of patients with a known status, 27% (12/45) were HIV-positive. The median symptom duration prior to presentation was 28 days, with females presenting later than males (84 vs. 28 days, P = 0.008).Conclusion: This study highlights areas where community and hospital-based management of TB could be improved to potentially reduce TB mortality, including earlier detection and treatment, improved bacteriological diagnosis and increased HIV testing

    AB - Setting: Mendi Provincial Hospital, Southern Highlands Province, Papua New Guinea (PNG).Background: PNG is a high burden country for tuberculosis (TB) and TB-human immunodeficiency virus (HIV). TB is the second most common cause of death in PNG.Objective: To identify the number of adult inpatients with TB who died between 1 January 2015 and 30 August 2017; describe these patients’ characteristics and identify contributing factors that could be modified.Design: This was a retrospective case series review.Results: Among 905 inpatients with TB during the study period, there were 90 deaths. The patients who died were older than those who survived (median age 40 years vs. 32 years, P = 0.011). The majority of patients who died lived less than 3 hours from the hospital (71%),were diagnosed after admission (79%) and were clinically diagnosed (77%). HIV status was not known in 50% of the deaths. Of patients with a known status, 27% (12/45) were HIV-positive. The median symptom duration prior to presentation was 28 days, with females presenting later than males (84 vs. 28 days, P = 0.008).Conclusion: This study highlights areas where community and hospital-based management of TB could be improved to potentially reduce TB mortality, including earlier detection and treatment, improved bacteriological diagnosis and increased HIV testing

    KW - death audit

    KW - preventable deaths

    KW - risk factors

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    DO - 10.5588/pha.18.0068

    M3 - Article

    VL - 9

    SP - S62-S67

    JO - Public Health Action

    JF - Public Health Action

    SN - 2220-8372

    IS - Supplement 1

    ER -

    Vakadem K, Anota A, Sa'avu M, Ramoni C, Comrie-Thomson L, Gale M et al. A mortality review of adult inpatients with tuberculosis in Mendi, Papua New Guinea. Public Health Action. 2019 Sep 21;9(Supplement 1):S62-S67. https://doi.org/10.5588/pha.18.0068