Abstract
Acyl radicals have been generated from α-keto acids using inexpensive and commercially available 2-chloro-thioxanthen-9-one as the photoredox catalyst under visible light illumination. These reactive species added to olefins or coupled with aryl halides via a bipyridyl-stabilized Ni(II) catalyst, enabling easy access to a diverse range of ketones. This reliable, atom-economical, and eco-friendly protocol is compatible with a wide range of functional groups.
Original language | English |
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Pages (from-to) | 6832-6837 |
Number of pages | 6 |
Journal | Organic Letters |
Volume | 22 |
Issue number | 17 |
DOIs | |
Publication status | Published - 4 Sept 2020 |