Adherence to treatment guidelines in the pharmacological management of chronic heart failure in an Australian population

Dao-Kuo Yao, Le-Xin Wang, Shane Curran, Patrick Ball

Research output: Contribution to journalArticleResearchpeer-review

Abstract

Background To document the pharmacotherapy of chronic heart failure (CHF) and to evaluate the adherence to treatment guidelines in Australian population. Methods The pharmacological management of 677 patients (female 46.7%, 75.5 ± 11.6 years) with CHF was retrospectively analyzed. Results The use of angiotensin converting enzyme (ACE) inhibitors/angiotensin receptor blockers (ARB) and β-blockers were 58.2 % and 34.7 %, respectively. Major reasons for non-use of ACE inhibitors/ARBs were hyperkalemia and elevated serum creatinine level. For patients who did not receive β-blockers, asthma and chronic obstructive pulmonary disease were the main contraindications. Treatment at or above target dosages for ACE inhibitors/ARBs and β-blockers was low for each medication (40.3% and 28.9%, respectively). Conclusions Evidenced-based medical therapies for heart failure were under used in a rural patient population. Further studies are required to develop processes to improve the optimal use of heart failure medications.
Original languageEnglish
Pages (from-to)88-92
Number of pages5
JournalJournal of Geriatric Cardiology
Volume8
Issue number2
DOIs
Publication statusPublished - 2011
Externally publishedYes

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Heart Failure
Angiotensin-Converting Enzyme Inhibitors
Pharmacology
Guidelines
Population
Hyperkalemia
Angiotensin Receptor Antagonists
Rural Population
Therapeutics
Chronic Obstructive Pulmonary Disease
Creatinine
Asthma
Drug Therapy
Serum

Cite this

Yao, Dao-Kuo ; Wang, Le-Xin ; Curran, Shane ; Ball, Patrick. / Adherence to treatment guidelines in the pharmacological management of chronic heart failure in an Australian population. In: Journal of Geriatric Cardiology. 2011 ; Vol. 8, No. 2. pp. 88-92.
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abstract = "Background To document the pharmacotherapy of chronic heart failure (CHF) and to evaluate the adherence to treatment guidelines in Australian population. Methods The pharmacological management of 677 patients (female 46.7{\%}, 75.5 ± 11.6 years) with CHF was retrospectively analyzed. Results The use of angiotensin converting enzyme (ACE) inhibitors/angiotensin receptor blockers (ARB) and β-blockers were 58.2 {\%} and 34.7 {\%}, respectively. Major reasons for non-use of ACE inhibitors/ARBs were hyperkalemia and elevated serum creatinine level. For patients who did not receive β-blockers, asthma and chronic obstructive pulmonary disease were the main contraindications. Treatment at or above target dosages for ACE inhibitors/ARBs and β-blockers was low for each medication (40.3{\%} and 28.9{\%}, respectively). Conclusions Evidenced-based medical therapies for heart failure were under used in a rural patient population. Further studies are required to develop processes to improve the optimal use of heart failure medications.",
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Adherence to treatment guidelines in the pharmacological management of chronic heart failure in an Australian population. / Yao, Dao-Kuo; Wang, Le-Xin; Curran, Shane; Ball, Patrick.

In: Journal of Geriatric Cardiology, Vol. 8, No. 2, 2011, p. 88-92.

Research output: Contribution to journalArticleResearchpeer-review

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N2 - Background To document the pharmacotherapy of chronic heart failure (CHF) and to evaluate the adherence to treatment guidelines in Australian population. Methods The pharmacological management of 677 patients (female 46.7%, 75.5 ± 11.6 years) with CHF was retrospectively analyzed. Results The use of angiotensin converting enzyme (ACE) inhibitors/angiotensin receptor blockers (ARB) and β-blockers were 58.2 % and 34.7 %, respectively. Major reasons for non-use of ACE inhibitors/ARBs were hyperkalemia and elevated serum creatinine level. For patients who did not receive β-blockers, asthma and chronic obstructive pulmonary disease were the main contraindications. Treatment at or above target dosages for ACE inhibitors/ARBs and β-blockers was low for each medication (40.3% and 28.9%, respectively). Conclusions Evidenced-based medical therapies for heart failure were under used in a rural patient population. Further studies are required to develop processes to improve the optimal use of heart failure medications.

AB - Background To document the pharmacotherapy of chronic heart failure (CHF) and to evaluate the adherence to treatment guidelines in Australian population. Methods The pharmacological management of 677 patients (female 46.7%, 75.5 ± 11.6 years) with CHF was retrospectively analyzed. Results The use of angiotensin converting enzyme (ACE) inhibitors/angiotensin receptor blockers (ARB) and β-blockers were 58.2 % and 34.7 %, respectively. Major reasons for non-use of ACE inhibitors/ARBs were hyperkalemia and elevated serum creatinine level. For patients who did not receive β-blockers, asthma and chronic obstructive pulmonary disease were the main contraindications. Treatment at or above target dosages for ACE inhibitors/ARBs and β-blockers was low for each medication (40.3% and 28.9%, respectively). Conclusions Evidenced-based medical therapies for heart failure were under used in a rural patient population. Further studies are required to develop processes to improve the optimal use of heart failure medications.

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