An introduction to clinical trial design

A. Schultz; B. R. Saville; J. A. Marsh; T. L. Snelling

doi:10.1016/j.prrv.2019.06.002

An introduction to clinical trial design

A. Schultz, B. R. Saville, J. A. Marsh, T. L. Snelling

Research output: Contribution to journal › Review article

Abstract

Clinicians and other decision makers in healthcare use results from clinical trials to inform practice. Interpretation of clinical trial results can be challenging, as weaknesses in trial design, data collection, analysis or reporting, can compromise the usefulness of results. A good working knowledge of clinical trial design is essential to expertly interpret and determine the validity and generalizability of the results. This manuscript will give a brief overview of clinical trial design including the strengths and limitations of various approaches. The focus will be on confirmatory clinical trials.

Original language	English
Pages (from-to)	30-35
Number of pages	6
Journal	Paediatric Respiratory Reviews
Volume	32
Early online date	26 Jun 2019
DOIs	https://doi.org/10.1016/j.prrv.2019.06.002
Publication status	Published - Nov 2019

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10.1016/j.prrv.2019.06.002

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abstract = "Clinicians and other decision makers in healthcare use results from clinical trials to inform practice. Interpretation of clinical trial results can be challenging, as weaknesses in trial design, data collection, analysis or reporting, can compromise the usefulness of results. A good working knowledge of clinical trial design is essential to expertly interpret and determine the validity and generalizability of the results. This manuscript will give a brief overview of clinical trial design including the strengths and limitations of various approaches. The focus will be on confirmatory clinical trials.",

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