Anthropometric cut-points for discriminating diabetes and metabolic syndrome among Arabs and Asians: The Kuwait Diabetes Epidemiology Program

Victor M. Oguoma, Neil T. Coffee, Saad Alsharrah, Mohamed Abu-Farha, Faisal H. Al-Refaei, Abdullah Alkandari, Fahd Al-Mulla, Mark Daniel

Research output: Contribution to journalArticlepeer-review

Abstract

This study aimed to determine anthropometric cut-points for screening diabetes and metabolic syndrome (MetS) in Arab and South Asian ethnic groups in Kuwait; and to compare the prevalence of MetS based on the ethnic-specific waist circumference (WC) cut-point and the International Diabetes Federation (IDF), and American Heart Association/National Heart, Lung, and Blood Institute (AHA/NHLBI) WC criteria. The national population-based survey dataset of diabetes and obesity in Kuwait adults aged 18-60 years were analysed. Age-adjusted logistic regression and receiver operating characteristic (ROC) analyses were conducted to evaluate for 3589 individuals the utility of WC, waist-to-height ratio (WHtR) and body mass index (BMI) to discriminate both diabetes and ≥3 CVD risk factors. Areas under the ROC curve were similar for WC, WHtR and BMI. In Arab men, WC, WHtR and BMI cut-offs for diabetes were 106 cm, 0.55, and 28 kg/m2; and for ≥3 CVD risk factors, 97cm, 0.55, and 28 kg/m2, respectively. In Arab women, cut-offs for diabetes were 107 cm, 0.65, and 33 kg/m2; and for ≥3 CVD risk factors, 93 cm, 0.60 and 30 kg/m2 respectively. WC cut-offs were higher for South Asian women than men. IDF-based WC cut-offs corresponded to a higher prevalence of MetS across gender and ethnic groups, compared to Kuwait-specific cut-offs. Any of the assessed anthropometric indices can be used in screening of diabetes and ≥3 CVD risk factors in Kuwaiti Arab and Asian populations. ROC values were similar. The WC threshold for screening MetS in Kuwaiti Arabs and South Asians are higher for women.

Original languageEnglish
Pages (from-to)1-25
Number of pages25
JournalBritish Journal of Nutrition
Early online date4 Mar 2021
DOIs
Publication statusE-pub ahead of print - 4 Mar 2021

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