Antigen capture immuno-chromatographic strip format in detecting parasite-specific antibodies to diagnose parasitic infections at clinical parasitology laboratories

A lateral flow immunoassay / immunochromatographic test strip assay is a technology that is widely applied for human diagnostics. These test strips are currently used for detection of infections (parasites) and allergy. It can guide clinicians for immediate treatment decisions. These antibody test platform is a convenient, rapid and sensitive detection tool which are specially designed for single use at point of care/need, i.e. outside thelaboratory. The primary competencies are the development, manufacturing and commercialisation of point of need lateral flow, microfludic and ELISA assay formats. These devices were designed for qualitative applications and could give high sensitivity, specificity and good stability. It is relatively cost effective and can handle small volume of patient’s samples. This paper describes principles of current formats, applications and its advantages and limitations.