Approaching the community about screening children for a multicentre malaria vaccine trial

Trudie Lang, Jayne Gould, Lorenz Von Seidlein, John Lusingu, S Mshamu, Sadiki Ismael, E Liheluka, D Kamuya, D Mwachiro, Ally Olotu, Patricia Njuguna, Phillip Bejon, Kevin Marsh, V Marsh, C Molyneux

Research output: Contribution to journalArticleResearchpeer-review

Abstract

Community sensitisation, as a component of community engagement, plays an important role in strengthening the ethics of community-based trials in developing countries and is fundamental to trial success. However, few researchers have shared their community sensitisation strategies and experiences. We report on our perspective as researchers on the sensitisation activities undertaken for a phase II malaria vaccine trial in Kilifi District (Kenya) and Korogwe District (Tanzania), with the aim of informing and guiding the operational planning of future trials. We report wide variability in recruitment rates within both sites; a variability that occurred against a backdrop of similarity in overall approaches to sensitisation across the two sites but significant differences in community exposure to biomedical research. We present a range of potential factors contributing to these differences in recruitment rates, which we believe are worth considering in future community sensitisation plans. We conclude by arguing for carefully designed social science research around the implementation and impact of community sensitisation activities.
Original languageEnglish
Pages (from-to)47-54
Number of pages8
JournalInternational Health
Volume4
Issue number1
DOIs
Publication statusPublished - 1 Mar 2012
Externally publishedYes

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Malaria Vaccines
sensitization
community
Research Personnel
district
Tanzania
Social Sciences
Kenya
Ethics
Developing Countries
Biomedical Research
social science
moral philosophy
developing country
planning
Research

Cite this

Lang, T., Gould, J., Von Seidlein, L., Lusingu, J., Mshamu, S., Ismael, S., ... Molyneux, C. (2012). Approaching the community about screening children for a multicentre malaria vaccine trial. International Health, 4(1), 47-54. https://doi.org/10.1016/j.inhe.2011.10.003
Lang, Trudie ; Gould, Jayne ; Von Seidlein, Lorenz ; Lusingu, John ; Mshamu, S ; Ismael, Sadiki ; Liheluka, E ; Kamuya, D ; Mwachiro, D ; Olotu, Ally ; Njuguna, Patricia ; Bejon, Phillip ; Marsh, Kevin ; Marsh, V ; Molyneux, C. / Approaching the community about screening children for a multicentre malaria vaccine trial. In: International Health. 2012 ; Vol. 4, No. 1. pp. 47-54.
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Lang, T, Gould, J, Von Seidlein, L, Lusingu, J, Mshamu, S, Ismael, S, Liheluka, E, Kamuya, D, Mwachiro, D, Olotu, A, Njuguna, P, Bejon, P, Marsh, K, Marsh, V & Molyneux, C 2012, 'Approaching the community about screening children for a multicentre malaria vaccine trial', International Health, vol. 4, no. 1, pp. 47-54. https://doi.org/10.1016/j.inhe.2011.10.003

Approaching the community about screening children for a multicentre malaria vaccine trial. / Lang, Trudie; Gould, Jayne; Von Seidlein, Lorenz; Lusingu, John; Mshamu, S; Ismael, Sadiki; Liheluka, E; Kamuya, D; Mwachiro, D; Olotu, Ally; Njuguna, Patricia; Bejon, Phillip; Marsh, Kevin; Marsh, V; Molyneux, C.

In: International Health, Vol. 4, No. 1, 01.03.2012, p. 47-54.

Research output: Contribution to journalArticleResearchpeer-review

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AU - Lang, Trudie

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AU - Mshamu, S

AU - Ismael, Sadiki

AU - Liheluka, E

AU - Kamuya, D

AU - Mwachiro, D

AU - Olotu, Ally

AU - Njuguna, Patricia

AU - Bejon, Phillip

AU - Marsh, Kevin

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AU - Molyneux, C

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AB - Community sensitisation, as a component of community engagement, plays an important role in strengthening the ethics of community-based trials in developing countries and is fundamental to trial success. However, few researchers have shared their community sensitisation strategies and experiences. We report on our perspective as researchers on the sensitisation activities undertaken for a phase II malaria vaccine trial in Kilifi District (Kenya) and Korogwe District (Tanzania), with the aim of informing and guiding the operational planning of future trials. We report wide variability in recruitment rates within both sites; a variability that occurred against a backdrop of similarity in overall approaches to sensitisation across the two sites but significant differences in community exposure to biomedical research. We present a range of potential factors contributing to these differences in recruitment rates, which we believe are worth considering in future community sensitisation plans. We conclude by arguing for carefully designed social science research around the implementation and impact of community sensitisation activities.

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