Associations between aggressive behaviour scores and cardiovascular risk factors in childhood

S Louise, N Warrington, P McCaskie, Wendy Oddy, Stephen Zubrick, Beth P Hands, T Mori, L Briollais, Sven Silburn, L Palmer, E Mattes, Lawrence Beilin

    Research output: Contribution to journalArticle

    Abstract

    Objective: To examine the influence of aggressive behaviour scores on cardiovascular disease (CVD) risk factors throughout childhood.

    Methods: This study utilized cross-sectional and longitudinal data from the Western Australian Pregnancy Cohort (Raine) Study (n = 2900). Aggressive behaviour scores were derived from the Child Behavior Checklist/4–18(CBCL), Youth Self-Report/11–18 (YSR) and Teacher Report Form/6–18 (TRF). CVD risk factors included body mass index (BMI), blood pressure, fasting lipids and homeostasis model of insulin resistance (HOMA-IR).

    Results: Girls with higher aggressive behaviour scores had higher BMI from 10 years of age (P ≤ 0.001), higher BMI trajectories throughout childhood (P = 0.0003) and at 14 years higher HOMA-IR (P = 0.008). At the 14-year survey, this equated to a difference of 1.7 kg/m2 in the predicted BMI between the extreme CBCL scores in girls (top 5% (CBCL ≥ 17) vs. CBCL score = 0). Boys with higher aggressive behaviour scores had higher BMI at 5 years (P = 0.002), lower diastolic pressure at 14 years (P = 0.002) and lower systolic blood pressure trajectories throughout childhood (P = 0.016).

    Conclusion: Aggressive behaviour influences BMI from early childhood in girls but not boys. If this association is causal, childhood offers the opportunity for early behavioural intervention for obesity prevention.

    Original languageEnglish
    Pages (from-to)319-328
    Number of pages10
    JournalPediatric Obesity
    Volume7
    Issue number4
    DOIs
    Publication statusPublished - Aug 2012

    Fingerprint Dive into the research topics of 'Associations between aggressive behaviour scores and cardiovascular risk factors in childhood'. Together they form a unique fingerprint.

  • Cite this

    Louise, S., Warrington, N., McCaskie, P., Oddy, W., Zubrick, S., Hands, B. P., Mori, T., Briollais, L., Silburn, S., Palmer, L., Mattes, E., & Beilin, L. (2012). Associations between aggressive behaviour scores and cardiovascular risk factors in childhood. Pediatric Obesity, 7(4), 319-328. https://doi.org/10.1111/j.2047-6310.2012.00047.x