Abstract
Objective: To examine the influence of anxious/depressed scores on cardiovascular risk factors throughout childhood.
Methods: Data from the Western Australian Pregnancy Cohort (Raine)
Study, a study of 2900 pregnancies recruited between 1989 and 1991, were used.
Anxious-depressed scores (derived from the Childhood Behavior Checklist), body
mass index (BMI) and blood pressure were measured at 5 (n = 1681), 8 (n =
1697), 10 (n = 1575) and 14 (n = 1386) years. At age 14 depressive symptom
scores (Beck Depression Inventory for Youth), anxious-depressed scores (Youth
Self-Report (YSR) and Teacher Report Form (TRF)) and fasting lipid, glucose and
insulin were also available. Cross sectional and longitudinal analyses were
conducted.
Results: At age 14, girls with higher anxious-depressed scores
had higher BMI (p≤0.005) and homeostasis model assessment-estimated insulin
resistance (p≤0.0001). This equated to a difference of 0.6kg/m 2 and 0.3 units in predicted BMI and HOMA-IR respectively
(top 5% vs. score of zero). Boys with higher anxious-depressed scores had lower
systolic blood pressure trajectories (p=0.024).
Conclusion: Depressive scores appear to have differing influences on BMI,
homeostasis model assessment-estimated insulin resistance and systolic blood
pressure in boys and girls. Paradoxically boys with higher anxious-depressed
scores had lower blood pressure throughout childhood.
Original language | English |
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Pages (from-to) | 345-350 |
Number of pages | 6 |
Journal | Preventive Medicine |
Volume | 54 |
Issue number | 5 |
DOIs | |
Publication status | Published - 1 May 2012 |