TY - JOUR
T1 - Bilateral diffuse pulmonary infiltrates secondary to malignant peritoneal mesothelioma – A rare clinical presentation
AU - Haygarth, Madeleine
AU - Zaw, Kyi Kyi
AU - Yachmenikova, Victoria
AU - Pokorny, Adrian M.J.
AU - Kwong, Kin Keung
AU - Heraganahally, Subash S.
PY - 2019/1/1
Y1 - 2019/1/1
N2 - Diffuse pulmonary metastasis secondary to primary peritoneal malignant mesothelioma is rarely reported in the literature. In this report we describe a 59-year-old Caucasian women with no known previous asbestos exposure presenting with bilateral diffuse pulmonary opacities in association with primary malignant peritoneal mesothelioma. The diagnosis was confirmed by ultrasound guided abdominal and bronchoscopy, trans-bronchial lung biopsy. The biopsy demonstrated positive staining with AE1/3, CK7, CK5/6, WT1, calretinin and D2 40. The cells were negative for BerEP4, PAX8, CA125, ER, CD34, ERG, P63, P40, Melan A, Gata3 and mammaglobin. The morphology and immunohistochemical profile supported a diagnosis of epithelioid malignant mesothelioma.
AB - Diffuse pulmonary metastasis secondary to primary peritoneal malignant mesothelioma is rarely reported in the literature. In this report we describe a 59-year-old Caucasian women with no known previous asbestos exposure presenting with bilateral diffuse pulmonary opacities in association with primary malignant peritoneal mesothelioma. The diagnosis was confirmed by ultrasound guided abdominal and bronchoscopy, trans-bronchial lung biopsy. The biopsy demonstrated positive staining with AE1/3, CK7, CK5/6, WT1, calretinin and D2 40. The cells were negative for BerEP4, PAX8, CA125, ER, CD34, ERG, P63, P40, Melan A, Gata3 and mammaglobin. The morphology and immunohistochemical profile supported a diagnosis of epithelioid malignant mesothelioma.
KW - Asbestos
KW - Malignant mesothelioma
KW - Peritoneal mesothelioma
KW - Pleural effusion
KW - Trans-bronchial lung biopsy
UR - http://www.scopus.com/inward/record.url?scp=85062477311&partnerID=8YFLogxK
U2 - 10.1016/j.rmcr.2019.03.003
DO - 10.1016/j.rmcr.2019.03.003
M3 - Article
C2 - 30937282
AN - SCOPUS:85062477311
VL - 26
SP - 326
EP - 327
JO - Respiratory Medicine Case Reports
JF - Respiratory Medicine Case Reports
SN - 2213-0071
ER -