Cardiovascular Risk Assessment in Prediabetes and Undiagnosed Diabetes Mellitus Study

International Collaboration Research Overview

Ezekiel (Uba) Nwose, Ross Richards, Kester Digban, P Bwititi, Gretchen Ennis, Kwang Yee, Victor Oguoma, Selma Liberato

    Research output: Contribution to journalArticleResearchpeer-review

    Abstract

    The study aims to develop a screening protocol for the risk of future cardiovascular disease and diabetes mellitus in people with prediabetes and undiagnosed diabetes; and to establish a framework for early identification and intervention of prediabetes including strategies for holistic management and monitoring of progression. The first phase is to identify prediabetes and undiagnosed diabetes in volunteers who are ≥18-years-old for 5 years. Point-of-care testing and questionnaire will be used to screen for prediabetes and cardiovascular disease. We anticipate screening more than 2000 individuals of both genders by the end of first phase. The second and third phases which shall run for 5-10 years will be longitudinal study involving participants identified in the first phase as having prediabetes without dyslipidaemia, or clinically established cardiovascular disease. The second phase shall focus on preventive management of risk of progress to diabetes with explicit diagnosis of cardiovascular disease. Oxidative stress measurements will be performed cum evaluation of the use of antioxidants, exercise, and nutrition. The third phase will include probing the development of diabetes and cardiovascular disease. Binomial logistic regression would be performed to generate and propose a model chart for the assessment of cardiovascular disease risk in prediabetes.
    Original languageEnglish
    Pages (from-to)625-630
    Number of pages6
    JournalNorth American Journal of Medical Sciences
    Volume5
    Issue number11
    DOIs
    Publication statusPublished - 2013

    Fingerprint

    Prediabetic State
    Diabetes Mellitus
    Cardiovascular Diseases
    Research
    Risk Management
    Dyslipidemias
    Longitudinal Studies
    Volunteers
    Oxidative Stress
    Antioxidants
    Logistic Models
    Exercise

    Cite this

    Nwose, Ezekiel (Uba) ; Richards, Ross ; Digban, Kester ; Bwititi, P ; Ennis, Gretchen ; Yee, Kwang ; Oguoma, Victor ; Liberato, Selma. / Cardiovascular Risk Assessment in Prediabetes and Undiagnosed Diabetes Mellitus Study : International Collaboration Research Overview. In: North American Journal of Medical Sciences. 2013 ; Vol. 5, No. 11. pp. 625-630.
    @article{9995acbf3c7145ad886425cd25fc50fb,
    title = "Cardiovascular Risk Assessment in Prediabetes and Undiagnosed Diabetes Mellitus Study: International Collaboration Research Overview",
    abstract = "The study aims to develop a screening protocol for the risk of future cardiovascular disease and diabetes mellitus in people with prediabetes and undiagnosed diabetes; and to establish a framework for early identification and intervention of prediabetes including strategies for holistic management and monitoring of progression. The first phase is to identify prediabetes and undiagnosed diabetes in volunteers who are ≥18-years-old for 5 years. Point-of-care testing and questionnaire will be used to screen for prediabetes and cardiovascular disease. We anticipate screening more than 2000 individuals of both genders by the end of first phase. The second and third phases which shall run for 5-10 years will be longitudinal study involving participants identified in the first phase as having prediabetes without dyslipidaemia, or clinically established cardiovascular disease. The second phase shall focus on preventive management of risk of progress to diabetes with explicit diagnosis of cardiovascular disease. Oxidative stress measurements will be performed cum evaluation of the use of antioxidants, exercise, and nutrition. The third phase will include probing the development of diabetes and cardiovascular disease. Binomial logistic regression would be performed to generate and propose a model chart for the assessment of cardiovascular disease risk in prediabetes.",
    keywords = "cardiovascular disease, cardiovascular risk, clinical evaluation, diabetes mellitus, disease course, early diagnosis, early intervention, evidence based practice, exercise, human, impaired glucose tolerance, information processing, longitudinal study, mass screening, nutrition, oxidative stress, pathogenesis, point of care testing, questionnaire, review, risk assessment, social work practice, translational research",
    author = "Nwose, {Ezekiel (Uba)} and Ross Richards and Kester Digban and P Bwititi and Gretchen Ennis and Kwang Yee and Victor Oguoma and Selma Liberato",
    year = "2013",
    doi = "10.4103/1947-2714.122303",
    language = "English",
    volume = "5",
    pages = "625--630",
    journal = "North American Journal of Medical Sciences",
    issn = "2250-1541",
    publisher = "Medknow Publications",
    number = "11",

    }

    Cardiovascular Risk Assessment in Prediabetes and Undiagnosed Diabetes Mellitus Study : International Collaboration Research Overview. / Nwose, Ezekiel (Uba); Richards, Ross; Digban, Kester; Bwititi, P; Ennis, Gretchen; Yee, Kwang; Oguoma, Victor ; Liberato, Selma.

    In: North American Journal of Medical Sciences, Vol. 5, No. 11, 2013, p. 625-630.

    Research output: Contribution to journalArticleResearchpeer-review

    TY - JOUR

    T1 - Cardiovascular Risk Assessment in Prediabetes and Undiagnosed Diabetes Mellitus Study

    T2 - International Collaboration Research Overview

    AU - Nwose, Ezekiel (Uba)

    AU - Richards, Ross

    AU - Digban, Kester

    AU - Bwititi, P

    AU - Ennis, Gretchen

    AU - Yee, Kwang

    AU - Oguoma, Victor

    AU - Liberato, Selma

    PY - 2013

    Y1 - 2013

    N2 - The study aims to develop a screening protocol for the risk of future cardiovascular disease and diabetes mellitus in people with prediabetes and undiagnosed diabetes; and to establish a framework for early identification and intervention of prediabetes including strategies for holistic management and monitoring of progression. The first phase is to identify prediabetes and undiagnosed diabetes in volunteers who are ≥18-years-old for 5 years. Point-of-care testing and questionnaire will be used to screen for prediabetes and cardiovascular disease. We anticipate screening more than 2000 individuals of both genders by the end of first phase. The second and third phases which shall run for 5-10 years will be longitudinal study involving participants identified in the first phase as having prediabetes without dyslipidaemia, or clinically established cardiovascular disease. The second phase shall focus on preventive management of risk of progress to diabetes with explicit diagnosis of cardiovascular disease. Oxidative stress measurements will be performed cum evaluation of the use of antioxidants, exercise, and nutrition. The third phase will include probing the development of diabetes and cardiovascular disease. Binomial logistic regression would be performed to generate and propose a model chart for the assessment of cardiovascular disease risk in prediabetes.

    AB - The study aims to develop a screening protocol for the risk of future cardiovascular disease and diabetes mellitus in people with prediabetes and undiagnosed diabetes; and to establish a framework for early identification and intervention of prediabetes including strategies for holistic management and monitoring of progression. The first phase is to identify prediabetes and undiagnosed diabetes in volunteers who are ≥18-years-old for 5 years. Point-of-care testing and questionnaire will be used to screen for prediabetes and cardiovascular disease. We anticipate screening more than 2000 individuals of both genders by the end of first phase. The second and third phases which shall run for 5-10 years will be longitudinal study involving participants identified in the first phase as having prediabetes without dyslipidaemia, or clinically established cardiovascular disease. The second phase shall focus on preventive management of risk of progress to diabetes with explicit diagnosis of cardiovascular disease. Oxidative stress measurements will be performed cum evaluation of the use of antioxidants, exercise, and nutrition. The third phase will include probing the development of diabetes and cardiovascular disease. Binomial logistic regression would be performed to generate and propose a model chart for the assessment of cardiovascular disease risk in prediabetes.

    KW - cardiovascular disease

    KW - cardiovascular risk

    KW - clinical evaluation

    KW - diabetes mellitus

    KW - disease course

    KW - early diagnosis

    KW - early intervention

    KW - evidence based practice

    KW - exercise

    KW - human

    KW - impaired glucose tolerance

    KW - information processing

    KW - longitudinal study

    KW - mass screening

    KW - nutrition

    KW - oxidative stress

    KW - pathogenesis

    KW - point of care testing

    KW - questionnaire

    KW - review

    KW - risk assessment

    KW - social work practice

    KW - translational research

    U2 - 10.4103/1947-2714.122303

    DO - 10.4103/1947-2714.122303

    M3 - Article

    VL - 5

    SP - 625

    EP - 630

    JO - North American Journal of Medical Sciences

    JF - North American Journal of Medical Sciences

    SN - 2250-1541

    IS - 11

    ER -