Case report: Fatal pediatric melioidosis despite optimal intensive care

Alice Young; Catherine Tacon; Simon Smith; Ben Reeves; Greg Wiseman; Josh Hanson

doi:10.4269/ajtmh.17-0650

Case report: Fatal pediatric melioidosis despite optimal intensive care

Alice Young, Catherine Tacon, Simon Smith, Ben Reeves, Greg Wiseman, Josh Hanson

Research output: Contribution to journal › Article › peer-review

Abstract

With prompt administration of appropriate antimicrobial therapy and access to modern intensive care support, fatal pediatric melioidosis is very unusual. We describe cases of two children in whom the possibility of melioidosis was recognized relatively early, but who died of the disease, despite receiving optimal supportive care. We discuss the resulting implications for bacterial virulence factors in disease pathogenesis.

Original language	English
Pages (from-to)	1691-1694
Number of pages	4
Journal	American Journal of Tropical Medicine and Hygiene
Volume	97
Issue number	6
DOIs	https://doi.org/10.4269/ajtmh.17-0650
Publication status	Published - Dec 2017

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title = "Case report: Fatal pediatric melioidosis despite optimal intensive care",

abstract = "With prompt administration of appropriate antimicrobial therapy and access to modern intensive care support, fatal pediatric melioidosis is very unusual. We describe cases of two children in whom the possibility of melioidosis was recognized relatively early, but who died of the disease, despite receiving optimal supportive care. We discuss the resulting implications for bacterial virulence factors in disease pathogenesis.",

author = "Alice Young and Catherine Tacon and Simon Smith and Ben Reeves and Greg Wiseman and Josh Hanson",

year = "2017",

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AU - Young, Alice

AU - Tacon, Catherine

AU - Smith, Simon

AU - Reeves, Ben

AU - Wiseman, Greg

AU - Hanson, Josh

PY - 2017/12

Y1 - 2017/12

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AB - With prompt administration of appropriate antimicrobial therapy and access to modern intensive care support, fatal pediatric melioidosis is very unusual. We describe cases of two children in whom the possibility of melioidosis was recognized relatively early, but who died of the disease, despite receiving optimal supportive care. We discuss the resulting implications for bacterial virulence factors in disease pathogenesis.

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JO - The American Journal of Tropical Medicine and Hygiene

JF - The American Journal of Tropical Medicine and Hygiene

SN - 0002-9637

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Case report: Fatal pediatric melioidosis despite optimal intensive care

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