@article{772f78f5444e48a8a07cd7511246b0bc,
title = "Case Report: Severe Congenital Malaria Acquired in Utero",
abstract = "Vertical transmission of Plasmodium falciparum is under-recognized and usually associated with asymptom-atic low-level parasitemia at birth. We report symptomatic congenital malaria presenting as a neonatal sepsis syndrome. The presence at birth of a high asexual parasitemia, gametocytemia, and splenomegaly indicated in utero rather than intrapartum transmission. The neonate was successfully treated with intravenous artesunate followed by oral dihydroartemisinin-piperaquine, without apparent adverse effects. ",
keywords = "artesunate, dihydroartemisinin plus piperaquine, antimalarial agent, artemisinin derivative, dihydroquinghaosu, piperaquine, quinoline derivative, article, case report, clinical feature, disease course, female, gametocytemia, human, intrauterine infection, malaria falciparum, newborn, newborn infection, newborn sepsis, parasitemia, Plasmodium falciparum, splenomegaly, symptom, vertical transmission, adult, disease transmission, pregnancy, Artesunate, Adult, Antimalarials, Artemisinins, Female, Humans, Infant, Newborn, Infectious Disease Transmission, Vertical, Malaria, Falciparum, Pregnancy, Quinolines",
author = "Poespoprodjo, {Jeanne Rini} and Afdal Hasanuddin and Wendelina Fobia and Paulus Sugiarto and Enny Kenangalem and Daniel Lampah and Emiliana Tijitra and Ric Price and Nicholas Anstey",
year = "2010",
month = apr,
day = "1",
doi = "10.4269/ajtmh.2010.09-0744",
language = "English",
volume = "82",
pages = "563--565",
journal = "American Journal of Tropical Medicine and Hygiene",
issn = "0002-9637",
publisher = "American Society of Tropical Medicine and Hygiene",
number = "4",
}
