Case Report: Severe Congenital Malaria Acquired in Utero

Jeanne Rini Poespoprodjo, Afdal Hasanuddin, Wendelina Fobia, Paulus Sugiarto, Enny Kenangalem, Daniel Lampah, Emiliana Tijitra, Ric Price, Nicholas Anstey

    Research output: Contribution to journalComment/debate


    Vertical transmission of Plasmodium falciparum is under-recognized and usually associated with asymptom-atic low-level parasitemia at birth. We report symptomatic congenital malaria presenting as a neonatal sepsis syndrome. The presence at birth of a high asexual parasitemia, gametocytemia, and splenomegaly indicated in utero rather than intrapartum transmission. The neonate was successfully treated with intravenous artesunate followed by oral dihydroartemisinin-piperaquine, without apparent adverse effects.
    Original languageEnglish
    Pages (from-to)563-565
    Number of pages3
    JournalAmerican Journal of Tropical Medicine and Hygiene
    Issue number4
    Publication statusPublished - 1 Apr 2010


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