Abstract
We report three cases of lymphocutaneous infection caused by the thermally dimorphic fungus, Sporothrix schenckii from Australia's tropical Northern Territory. Two cases were acquired locally, making them the first to be reported from this region. All three cases presented with ulceration in the limb; however, the classical sporotrichoid spread was present only in the first two cases. Their occurrence within several weeks of each other was suggestive of a common source of environmental contamination such as hay used as garden mulch. Diagnoses were delayed in each case, with each patient having substantial exposure to ineffective antibiotics before the correct diagnosis was made. These cases bring the total number of reported sporotrichosis cases in Australia since 1951 to 199. Lessons from these cases are to consider the diagnosis of sporotrichosis in lesions of typical appearance, even in geographical settings from where this pathogen has not previously been reported.
| Original language | English |
|---|---|
| Pages (from-to) | 1263-1268 |
| Number of pages | 6 |
| Journal | American Journal of Tropical Medicine and Hygiene |
| Volume | 91 |
| Issue number | 6 |
| DOIs | |
| Publication status | Published - 1 Dec 2014 |
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Case Report : Sporotrichosis from the northern territory of Australia. / Subedi, Shradha; Kidd, Sarah E.; Baird, Robert W.; Coatsworth, Nicholas; Ralph, Anna.
In: American Journal of Tropical Medicine and Hygiene, Vol. 91, No. 6, 01.12.2014, p. 1263-1268.Research output: Contribution to journal › Article › Research › peer-review
TY - JOUR
T1 - Case Report
T2 - Sporotrichosis from the northern territory of Australia
AU - Subedi, Shradha
AU - Kidd, Sarah E.
AU - Baird, Robert W.
AU - Coatsworth, Nicholas
AU - Ralph, Anna
PY - 2014/12/1
Y1 - 2014/12/1
N2 - We report three cases of lymphocutaneous infection caused by the thermally dimorphic fungus, Sporothrix schenckii from Australia's tropical Northern Territory. Two cases were acquired locally, making them the first to be reported from this region. All three cases presented with ulceration in the limb; however, the classical sporotrichoid spread was present only in the first two cases. Their occurrence within several weeks of each other was suggestive of a common source of environmental contamination such as hay used as garden mulch. Diagnoses were delayed in each case, with each patient having substantial exposure to ineffective antibiotics before the correct diagnosis was made. These cases bring the total number of reported sporotrichosis cases in Australia since 1951 to 199. Lessons from these cases are to consider the diagnosis of sporotrichosis in lesions of typical appearance, even in geographical settings from where this pathogen has not previously been reported.
AB - We report three cases of lymphocutaneous infection caused by the thermally dimorphic fungus, Sporothrix schenckii from Australia's tropical Northern Territory. Two cases were acquired locally, making them the first to be reported from this region. All three cases presented with ulceration in the limb; however, the classical sporotrichoid spread was present only in the first two cases. Their occurrence within several weeks of each other was suggestive of a common source of environmental contamination such as hay used as garden mulch. Diagnoses were delayed in each case, with each patient having substantial exposure to ineffective antibiotics before the correct diagnosis was made. These cases bring the total number of reported sporotrichosis cases in Australia since 1951 to 199. Lessons from these cases are to consider the diagnosis of sporotrichosis in lesions of typical appearance, even in geographical settings from where this pathogen has not previously been reported.
KW - amoxicillin plus clavulanic acid
KW - cefalexin
KW - ciprofloxacin
KW - cotrimoxazole
KW - itraconazole
KW - antifungal agent
KW - adult
KW - antibiotic therapy
KW - Article
KW - Australia
KW - bacterium culture
KW - case report
KW - drug dose increase
KW - hand injury
KW - hay
KW - histopathology
KW - human
KW - human tissue
KW - male
KW - middle aged
KW - mulch
KW - nonhuman
KW - punch biopsy
KW - Sporothrix schenckii
KW - sporotrichosis
KW - squamous cell carcinoma
KW - ulcer
KW - pathology
KW - Fungi
KW - Antifungal Agents
KW - Humans
KW - Itraconazole
KW - Male
KW - Middle Aged
KW - Northern Territory
KW - Sporotrichosis
UR - http://www.scopus.com/inward/record.url?scp=84918795565&partnerID=8YFLogxK
U2 - 10.4269/ajtmh.14-0456
DO - 10.4269/ajtmh.14-0456
M3 - Article
VL - 91
SP - 1263
EP - 1268
JO - The American Journal of Tropical Medicine and Hygiene
JF - The American Journal of Tropical Medicine and Hygiene
SN - 0002-9637
IS - 6
ER -