Case report: West Nile Virus (Kunjin Subtype) Disease in the Northern Territory of Australia - A Case of Encephalitis and Review of All Reported Cases

Timothy Gray, James Burrow, Peter Markey, Peter I Whelan, Justin Jackson, W Smith, Bart Currie

    Research output: Contribution to journalArticlepeer-review

    Abstract

    West Nile virus Kunjin subtype (WNV/KUNV) is enzootic across the tropical north of Australia, with epizootic spread into other jurisdictions. The clinical spectrum of illness in humans is poorly described. We report a clinical case of WNV/KUNV encephalitis and performed a retrospective chart audit of all cases of WNV/KUNV notified in the Northern Territory from 1992 to 2010. Thirteen cases of WNV/KUNV disease were identified; case notes were available for 10 of these presentations. Six of these patients had confirmed infection and presented with neuroinvasive illness, whereas the other four suspect cases comprised three cases with arthralgia, myalgia, and/or rash and one case with fever alone. On the available evidence, WNV/KUNV is of lower virulence compared with the New York 1999 strain. Difficulties in serological diagnosis, especially when paired acute and convalescent sera are not available, may adversely impact the accuracy of the epidemiological and clinical understanding of this virus. Copyright � 2011 by The American Society of Tropical Medicine and Hygiene.
    Original languageEnglish
    Pages (from-to)952-956
    Number of pages5
    JournalAmerican Journal of Tropical Medicine and Hygiene
    Volume85
    Issue number5
    DOIs
    Publication statusPublished - 2011

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