Zementaugmentation an der Wirbelsäule

Was ist biomechanisch zu beachten?

Translated title of the contribution: Cement augmentation on the spine: Biomechanical considerations

J. P. Kolb, L. Weiser, R. A. Kueny, G. Huber, J. M. Rueger, W. Lehmann

Research output: Contribution to journalArticleResearchpeer-review

Abstract

Background: Vertebral compression fractures are the most common osteoporotic fractures. Since the introduction of vertebroplasty and screw augmentation, the management of osteoporotic fractures has changed significantly. Aims: The biomechanical characteristics of the risk of adjacent fractures and novel treatment modalities for osteoporotic vertebral fractures, including pure cement augmentation by vertebroplasty, and cement augmentation of screws for posterior instrumentation, are explored. Materials and methods: Eighteen human osteoporotic lumbar spines (L1–5) adjacent to vertebral bodies after vertebroplasty were tested in a servo-hydraulic machine. As augmentation compounds we used standard cement and a modified low-strength cement. Different anchoring pedicle screws were tested with and without cement augmentation in another cohort of human specimens with a simple pull-out test and a fatigue test that better reflects physiological conditions. Results: Cement augmentation in the osteoporotic spine leads to greater biomechanical stability. However, change in vertebral stiffness resulted in alterations with the risk of adjacent fractures. By using a less firm cement compound, the risk of adjacent fractures is significantly reduced. Both screw augmentation techniques resulted in a significant increase in the withdrawal force compared with the group without cement. Augmentation using perforated screws showed the highest stability in the fatigue test. Discussion and conclusion: The augmentation of cement leads to a significant change in the biomechanical properties. Differences in the stability of adjacent vertebral bodies increase the risk of adjacent fractures, which could be mitigated by a modified cement compound with reduced strength. Screws that were specifically designed for cement application displayed greatest stability in the fatigue test.

Original languageGerman
Pages (from-to)672-680
Number of pages9
JournalOrthopade
Volume44
Issue number9
DOIs
Publication statusPublished - 22 Sep 2015
Externally publishedYes

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Vertebroplasty
Osteoporotic Fractures
Spine
Fatigue
Compression Fractures
Therapeutics

Cite this

Kolb, J. P., Weiser, L., Kueny, R. A., Huber, G., Rueger, J. M., & Lehmann, W. (2015). Zementaugmentation an der Wirbelsäule: Was ist biomechanisch zu beachten? Orthopade, 44(9), 672-680. https://doi.org/10.1007/s00132-015-3134-8
Kolb, J. P. ; Weiser, L. ; Kueny, R. A. ; Huber, G. ; Rueger, J. M. ; Lehmann, W. / Zementaugmentation an der Wirbelsäule : Was ist biomechanisch zu beachten?. In: Orthopade. 2015 ; Vol. 44, No. 9. pp. 672-680.
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abstract = "Background: Vertebral compression fractures are the most common osteoporotic fractures. Since the introduction of vertebroplasty and screw augmentation, the management of osteoporotic fractures has changed significantly. Aims: The biomechanical characteristics of the risk of adjacent fractures and novel treatment modalities for osteoporotic vertebral fractures, including pure cement augmentation by vertebroplasty, and cement augmentation of screws for posterior instrumentation, are explored. Materials and methods: Eighteen human osteoporotic lumbar spines (L1–5) adjacent to vertebral bodies after vertebroplasty were tested in a servo-hydraulic machine. As augmentation compounds we used standard cement and a modified low-strength cement. Different anchoring pedicle screws were tested with and without cement augmentation in another cohort of human specimens with a simple pull-out test and a fatigue test that better reflects physiological conditions. Results: Cement augmentation in the osteoporotic spine leads to greater biomechanical stability. However, change in vertebral stiffness resulted in alterations with the risk of adjacent fractures. By using a less firm cement compound, the risk of adjacent fractures is significantly reduced. Both screw augmentation techniques resulted in a significant increase in the withdrawal force compared with the group without cement. Augmentation using perforated screws showed the highest stability in the fatigue test. Discussion and conclusion: The augmentation of cement leads to a significant change in the biomechanical properties. Differences in the stability of adjacent vertebral bodies increase the risk of adjacent fractures, which could be mitigated by a modified cement compound with reduced strength. Screws that were specifically designed for cement application displayed greatest stability in the fatigue test.",
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Kolb, JP, Weiser, L, Kueny, RA, Huber, G, Rueger, JM & Lehmann, W 2015, 'Zementaugmentation an der Wirbelsäule: Was ist biomechanisch zu beachten?', Orthopade, vol. 44, no. 9, pp. 672-680. https://doi.org/10.1007/s00132-015-3134-8

Zementaugmentation an der Wirbelsäule : Was ist biomechanisch zu beachten? / Kolb, J. P.; Weiser, L.; Kueny, R. A.; Huber, G.; Rueger, J. M.; Lehmann, W.

In: Orthopade, Vol. 44, No. 9, 22.09.2015, p. 672-680.

Research output: Contribution to journalArticleResearchpeer-review

TY - JOUR

T1 - Zementaugmentation an der Wirbelsäule

T2 - Was ist biomechanisch zu beachten?

AU - Kolb, J. P.

AU - Weiser, L.

AU - Kueny, R. A.

AU - Huber, G.

AU - Rueger, J. M.

AU - Lehmann, W.

PY - 2015/9/22

Y1 - 2015/9/22

N2 - Background: Vertebral compression fractures are the most common osteoporotic fractures. Since the introduction of vertebroplasty and screw augmentation, the management of osteoporotic fractures has changed significantly. Aims: The biomechanical characteristics of the risk of adjacent fractures and novel treatment modalities for osteoporotic vertebral fractures, including pure cement augmentation by vertebroplasty, and cement augmentation of screws for posterior instrumentation, are explored. Materials and methods: Eighteen human osteoporotic lumbar spines (L1–5) adjacent to vertebral bodies after vertebroplasty were tested in a servo-hydraulic machine. As augmentation compounds we used standard cement and a modified low-strength cement. Different anchoring pedicle screws were tested with and without cement augmentation in another cohort of human specimens with a simple pull-out test and a fatigue test that better reflects physiological conditions. Results: Cement augmentation in the osteoporotic spine leads to greater biomechanical stability. However, change in vertebral stiffness resulted in alterations with the risk of adjacent fractures. By using a less firm cement compound, the risk of adjacent fractures is significantly reduced. Both screw augmentation techniques resulted in a significant increase in the withdrawal force compared with the group without cement. Augmentation using perforated screws showed the highest stability in the fatigue test. Discussion and conclusion: The augmentation of cement leads to a significant change in the biomechanical properties. Differences in the stability of adjacent vertebral bodies increase the risk of adjacent fractures, which could be mitigated by a modified cement compound with reduced strength. Screws that were specifically designed for cement application displayed greatest stability in the fatigue test.

AB - Background: Vertebral compression fractures are the most common osteoporotic fractures. Since the introduction of vertebroplasty and screw augmentation, the management of osteoporotic fractures has changed significantly. Aims: The biomechanical characteristics of the risk of adjacent fractures and novel treatment modalities for osteoporotic vertebral fractures, including pure cement augmentation by vertebroplasty, and cement augmentation of screws for posterior instrumentation, are explored. Materials and methods: Eighteen human osteoporotic lumbar spines (L1–5) adjacent to vertebral bodies after vertebroplasty were tested in a servo-hydraulic machine. As augmentation compounds we used standard cement and a modified low-strength cement. Different anchoring pedicle screws were tested with and without cement augmentation in another cohort of human specimens with a simple pull-out test and a fatigue test that better reflects physiological conditions. Results: Cement augmentation in the osteoporotic spine leads to greater biomechanical stability. However, change in vertebral stiffness resulted in alterations with the risk of adjacent fractures. By using a less firm cement compound, the risk of adjacent fractures is significantly reduced. Both screw augmentation techniques resulted in a significant increase in the withdrawal force compared with the group without cement. Augmentation using perforated screws showed the highest stability in the fatigue test. Discussion and conclusion: The augmentation of cement leads to a significant change in the biomechanical properties. Differences in the stability of adjacent vertebral bodies increase the risk of adjacent fractures, which could be mitigated by a modified cement compound with reduced strength. Screws that were specifically designed for cement application displayed greatest stability in the fatigue test.

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KW - Compression fractures

KW - Osteoporosis

KW - pedicle screws

KW - Vertebroplasty

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DO - 10.1007/s00132-015-3134-8

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JO - Der Orthopaede

JF - Der Orthopaede

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