@article{30f3fec50ff04b318bbc4816eeee6051,
title = "Chronic cough related to acute viral bronchiolitis in children: CHEST Expert Panel Report",
abstract = "Background: Acute bronchiolitis is common in young children, and some children develop chronic cough after their bronchiolitis. We thus undertook systematic reviews based on key questions (KQs) using the PICO (Population, Intervention, Comparison, Outcome) format. The KQs were: Among children with chronic cough (> 4 weeks) after acute viral bronchiolitis, how effective are the following interventions in improving the resolution of cough?: (1) Antibiotics. If so what type and for how long? (2) Asthma medications (inhaled steroids, beta2 agonist, montelukast); and (3) Inhaled osmotic agents like hypertonic saline?Methods: We used the CHEST expert cough panel{\textquoteright}s protocol and the American College of Chest Physicians (CHEST) methodological guidelines and GRADE framework. Data from the systematic reviews in conjunction with patients{\textquoteright} values and preferences and the clinical context were used to form these suggestions. Delphi methodology was used to obtain consensus.Results: Several studies and systematic reviews on the efficacy of the three types of interventions listed in the introduction were found but no data were relevant to our KQs. Thus, no recommendations on using the interventions above could be formulated.Conclusions: The panel made several consensus-based suggestions and identified directions for future studies to advance the field of managing chronic cough post-acute bronchiolitis in children.",
keywords = "cough, evidence-based medicine, guidelines",
author = "{CHEST Expert Cough Panel} and Chang, {Anne B.} and John Oppenheimer and Rubin, {Bruce K.} and Miles Weinberger and Irwin, {Richard S.} and Adams, {Todd M.} and Altman, {Kenneth W.} and Elie Azoulay and Barker, {Alan F.} and Birring, {Surinder S.} and Fiona Blackhall and Bolser, {Donald C.} and Boulet, {Louis Philippe} and Braman, {Sidney S.} and Christopher Brightling and Priscilla Callahan-Lyon and Chang, {Anne B.} and Terrie Cowley and Paul Davenport and Satoru Ebihara and {El Solh}, {Ali A.} and Patricio Escalante and Field, {Stephen K.} and Dina Fisher and French, {Cynthia T.} and Peter Gibson and Philip Gold and Harding, {Susan M.} and Anthony Harnden and Hill, {Adam T.} and Irwin, {Richard S.} and Kahrilas, {Peter J.} and Joanne Kavanagh and Keogh, {Karina A.} and Kefang Lai and Lane, {Andrew P.} and Kaiser Lim and Madison, {J. Mark} and Malesker, {Mark A.} and Stuart Mazzone and Lorcan McGarvey and Metlay, {Joshua P.} and Alex Molasoitis and Abigail Moore and Murad, {M. Hassan} and Mangala Narasimhan and Nguyen, {Huong Q.} and Peter Newcombe and John Oppenheimer and Restrepo, {Marcos I.} and Mark Rosen and Bruce Rubin and Ryu, {Jay H.} and Sonal Singh and Smith, {Maeve P.} and Tarlo, {Susan M.} and Julie Turmel and Vertigan, {Anne E.} and Gang Wang and Miles Weinberger",
year = "2018",
month = aug
day = "1",
doi = "10.1016/j.chest.2018.04.019",
language = "English",
volume = "154",
pages = "378--382",
journal = "Chest",
issn = "0012-3692",
publisher = "American College of Chest Physicians",
number = "2",
}