Paul Lawton, Joan Cunningham, Narelle Hadlow, Yuejen Zhao, Matthew D. Jose

    Research output: Contribution to journalMeeting Abstract


    Aim: To determine the prevalence and progression of measured chronic kidney disease (CKD) across a region with a high incidence of treated end‐stage kidney disease (ESKD).

    Background: The incidence of treated ESKD in the Northern Territory of Australia (NT) is three‐to‐four times national figures. Individual Indigenous community surveys have a much higher rate of treated ESKD and a very high prevalence of albuminuria compared to national rates. The overall prevalence and rate of progression of CKD in the region have not been described.

    Methods: Using a retrospective de‐identified extraction of all records with a serum creatinine or urinary albumin‐to‐creatinine ratio from the single largest ambulatory pathology provider to the Top End of the NT between 1st February 2002 and 31st December 2011, we calculated the yearly total and age‐specific prevalence of measured microalbuminuria, overt albuminuria and estimated glomerular filtration rate (eGFR) less than 60 mL/min/1.73 m2, and the prevalence of progressive CKD.

    Results: Over almost ten years 495,672 tests were done for 127,526 individuals, covering at most 26.3% of the adult estimated resident population. There was a steady increase in the proportion tested across all health districts in the region, more prominent in non‐urban districts. In 2009, the overall regional prevalence of measured microalbuminuria and overt albuminuria was 1.5%, overt albuminuria alone 0.7% and eGFR<60 1.3%, with considerably higher rates in remote health districts and older people. Rates of progressive disease were extremely high, particularly for those with albuminuria.

    The rates of testing, particularly in districts of high measured prevalence of markers of CKD, are encouraging. However, extremely high rates of progression of CKD are troubling. Further study would require analysis of linked datasets.
    Original languageEnglish
    Article number084
    Pages (from-to)39-40
    Number of pages2
    Issue numberS4
    Publication statusPublished - 2014

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