Clinical Evaluation of a Type III Secretion System Real-Time PCR Assay for Diagnosing Melioidosis

Ella Meumann, R Novak, D Gal, Mirjam Kaestli, Mark Mayo, Josh Hanson, E Spencer, Mindy Glass, J Gee, P Wilkins, Bart Currie

    Research output: Contribution to journalArticle

    Abstract

    A Burkholderia pseudomallei type III secretion system real-time PCR assay was evaluated on clinical specimens in a region where melioidosis is endemic. The PCR was positive in 30/33 (91%) patients with culture-confirmed melioidosis. All six patients with melioidosis septic shock were blood PCR positive, suggesting potential for rapid diagnosis and commencement of appropriate therapy. Copyright � 2006, American Society for Microbiology. All Rights Reserved.
    Original languageEnglish
    Pages (from-to)3028-3030
    Number of pages3
    JournalJournal of Clinical Microbiology
    Volume44
    Issue number8
    Publication statusPublished - 2006

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