@article{5dcdf75ac2224761b37b5044d11f91a2,
title = "Comparative Accuracy of the InBios Scrub Typhus Detect IgM Rapid Test for the Detection of IgM Antibodies by Using Conventional Serology",
abstract = "This study investigated the comparative accuracy of a recombinant 56-kDa type-specific antigen-based rapid diagnostic test (RDT) for scrub typhus for the detection of IgM antibodies by using conventional serology in well-characterized serum samples from undifferentiated febrile illness patients. The RDT showed high specificity and promising comparative accuracy, with 82% sensitivity and 98% specificity for samples defined positive at an IgM indirect immunofluorescence assay positivity cutoff titer of ≥1:1,600 versus 92% and 95% at ≥1:6,400, respectively. ",
keywords = "immunoglobulin M, antibody detection, antibody titer, Article, blood sampling, controlled study, diagnostic accuracy, diagnostic test accuracy study, human, immunoaffinity chromatography, immunofluorescence test, intermethod comparison, priority journal, rapid diagnostic test, rapid test, scrub typhus, sensitivity and specificity, serology",
author = "Kingston, {Hugh William Fluellen} and Blacksell, {Stuart D.} and Ampai Tanganuchitcharnchai and Achara Laongnualpanich and Buddha Basnyat and Nicholas Day and Paris, {Daniel H}",
year = "2015",
doi = "10.1128/CVI.00390-15",
language = "English",
volume = "22",
pages = "1130--1132",
journal = "Clinical and Vaccine Immunology",
issn = "1071-412X",
publisher = "American Society for Microbiology",
number = "10",
}