@article{a5d535b688c34e878432fa596fa70135,
title = "Cough Hypersensitivity Syndrome: Why Its Use Is Inappropriate in Children",
abstract = "In children and adults, chronic cough is a common symptom presenting to health professionals worldwide. It is internationally accepted that children with chronic cough should be managed with pediatric specific management guidelines. The newly proposed clinical entity of {\textquoteleft}cough hypersensitivity syndrome{\textquoteright} has gained significant attention in adult literature. Given the significant differences between childhood and adult chronic cough, including in respiratory physiology and anatomy, and cough sensitivity, we address the suitability of the use of cough hypersensitivity syndrome in children. We explore these differences between childhood and adult chronic cough, explain what cough hypersensitivity is and highlight why the term cough hypersensitivity syndrome should not be used in children.",
keywords = "children, cough, evidence, hypersensitivity, review",
author = "Chang, {Anne B.} and Irwin, {Richard S.} and O{\textquoteright}Farrell, {Hannah E.} and Dicpinigaitis, {Peter V.} and Suhani Goel and Ahmad Kantar and Marchant, {Julie M.}",
note = "Funding Information: H.E.O., S.G. and A.K. declare no conflict of interest. R.S.I. discloses that he is the Chair of the CHEST Expert Cough Panel and Co-developer of the Punum Cough Severity and Cough Quality of Life (CQLQ) patient-reported outcome measures. A.B.C. reports multiple grants from NHMRC and other fees to the institution from work relating to IDMC membership of an unlicensed vaccine (GSK), unlicensed monoclonal antibody for RSV (AZ) and a COVID-19 vaccine (Moderna), and advisor for study design (Zambon and Boehringer) outside the submitted work. P.V.D. reports remuneration for consultancy from Bayer AG, Bellus Health, Chiesi, Merck, and Shionogi. Publisher Copyright: {\textcopyright} 2023 by the authors.",
year = "2023",
month = aug,
doi = "10.3390/jcm12154879",
language = "English",
volume = "12",
pages = "1--12",
journal = "Journal of Clinical Medicine",
issn = "2077-0383",
publisher = "Multidisciplinary Digital Publishing Institute (MDPI)",
number = "15",
}