Current evidence on auricular therapy for chemotherapy-induced nausea and vomiting in cancer patients

A systematic review of randomized controlled trials

Jing Yu Tan, Alexander Molassiotis, Tao Wang, Lorna K P Suen

Research output: Contribution to journalArticleResearchpeer-review

3 Downloads (Pure)

Abstract

Auricular therapy (AT) has been historically viewed as a convenient approach adjunct to pharmacological therapy for cancer patients with chemotherapy-induced nausea and vomiting (CINV). The aim of this study was to assess the evidence of the therapeutic effect of AT for CINV management in cancer patients. Relevant randomized controlled trials were retrieved from 12 electronic databases without language restrictions. Meanwhile, manual search was conducted for Chinese journals on complementary medicine published within the last five years, and the reference lists of included studies were also checked to identify any possible eligible studies. Twenty-one studies with 1713 participants were included. The effect rate of AT for managing acute CINV ranged from 44.44% to 93.33% in the intervention groups and 15% to 91.67% in the control groups. For delayed CINV, it was 62.96% to 100% and 25% to 100%, respectively. AT seems to be a promising approach in managing CINV. However, the level of evidence was low and the definite effect cannot be concluded as there were significant methodological flaws identified in the analyzed studies. The implications drawn from the 21 studies put some clues for future practice in this area including the need to conduct more rigorously designed randomized controlled trials.

Original languageEnglish
Article number430796
Pages (from-to)1-18
Number of pages18
JournalEvidence-Based Complementary and Alternative Medicine
Volume2014
DOIs
Publication statusPublished - 25 Nov 2014
Externally publishedYes

Fingerprint

Nausea
Vomiting
Randomized Controlled Trials
Drug Therapy
Neoplasms
Therapeutics
Therapeutic Uses
Complementary Therapies
Language
Databases
Pharmacology
Control Groups

Cite this

@article{b4863d18a3cc47db97371af37f5cf39b,
title = "Current evidence on auricular therapy for chemotherapy-induced nausea and vomiting in cancer patients: A systematic review of randomized controlled trials",
abstract = "Auricular therapy (AT) has been historically viewed as a convenient approach adjunct to pharmacological therapy for cancer patients with chemotherapy-induced nausea and vomiting (CINV). The aim of this study was to assess the evidence of the therapeutic effect of AT for CINV management in cancer patients. Relevant randomized controlled trials were retrieved from 12 electronic databases without language restrictions. Meanwhile, manual search was conducted for Chinese journals on complementary medicine published within the last five years, and the reference lists of included studies were also checked to identify any possible eligible studies. Twenty-one studies with 1713 participants were included. The effect rate of AT for managing acute CINV ranged from 44.44{\%} to 93.33{\%} in the intervention groups and 15{\%} to 91.67{\%} in the control groups. For delayed CINV, it was 62.96{\%} to 100{\%} and 25{\%} to 100{\%}, respectively. AT seems to be a promising approach in managing CINV. However, the level of evidence was low and the definite effect cannot be concluded as there were significant methodological flaws identified in the analyzed studies. The implications drawn from the 21 studies put some clues for future practice in this area including the need to conduct more rigorously designed randomized controlled trials.",
keywords = "antineoplastic agent, acupuncture, adverse drug reaction, anxiety, Article, auricular therapy, cancer chemotherapy, cancer patient, chemotherapy induced nausea and vomiting, depression, human, randomized controlled trial (topic), systematic review, therapy, therapy effect, treatment duration",
author = "Tan, {Jing Yu} and Alexander Molassiotis and Tao Wang and Suen, {Lorna K P}",
year = "2014",
month = "11",
day = "25",
doi = "10.1155/2014/430796",
language = "English",
volume = "2014",
pages = "1--18",
journal = "Evidence-Based Complementary and Alternative Medicine",
issn = "1741-427X",
publisher = "Hindawi Publishing Corporation",

}

Current evidence on auricular therapy for chemotherapy-induced nausea and vomiting in cancer patients : A systematic review of randomized controlled trials. / Tan, Jing Yu; Molassiotis, Alexander; Wang, Tao; Suen, Lorna K P.

In: Evidence-Based Complementary and Alternative Medicine, Vol. 2014, 430796, 25.11.2014, p. 1-18.

Research output: Contribution to journalArticleResearchpeer-review

TY - JOUR

T1 - Current evidence on auricular therapy for chemotherapy-induced nausea and vomiting in cancer patients

T2 - A systematic review of randomized controlled trials

AU - Tan, Jing Yu

AU - Molassiotis, Alexander

AU - Wang, Tao

AU - Suen, Lorna K P

PY - 2014/11/25

Y1 - 2014/11/25

N2 - Auricular therapy (AT) has been historically viewed as a convenient approach adjunct to pharmacological therapy for cancer patients with chemotherapy-induced nausea and vomiting (CINV). The aim of this study was to assess the evidence of the therapeutic effect of AT for CINV management in cancer patients. Relevant randomized controlled trials were retrieved from 12 electronic databases without language restrictions. Meanwhile, manual search was conducted for Chinese journals on complementary medicine published within the last five years, and the reference lists of included studies were also checked to identify any possible eligible studies. Twenty-one studies with 1713 participants were included. The effect rate of AT for managing acute CINV ranged from 44.44% to 93.33% in the intervention groups and 15% to 91.67% in the control groups. For delayed CINV, it was 62.96% to 100% and 25% to 100%, respectively. AT seems to be a promising approach in managing CINV. However, the level of evidence was low and the definite effect cannot be concluded as there were significant methodological flaws identified in the analyzed studies. The implications drawn from the 21 studies put some clues for future practice in this area including the need to conduct more rigorously designed randomized controlled trials.

AB - Auricular therapy (AT) has been historically viewed as a convenient approach adjunct to pharmacological therapy for cancer patients with chemotherapy-induced nausea and vomiting (CINV). The aim of this study was to assess the evidence of the therapeutic effect of AT for CINV management in cancer patients. Relevant randomized controlled trials were retrieved from 12 electronic databases without language restrictions. Meanwhile, manual search was conducted for Chinese journals on complementary medicine published within the last five years, and the reference lists of included studies were also checked to identify any possible eligible studies. Twenty-one studies with 1713 participants were included. The effect rate of AT for managing acute CINV ranged from 44.44% to 93.33% in the intervention groups and 15% to 91.67% in the control groups. For delayed CINV, it was 62.96% to 100% and 25% to 100%, respectively. AT seems to be a promising approach in managing CINV. However, the level of evidence was low and the definite effect cannot be concluded as there were significant methodological flaws identified in the analyzed studies. The implications drawn from the 21 studies put some clues for future practice in this area including the need to conduct more rigorously designed randomized controlled trials.

KW - antineoplastic agent, acupuncture

KW - adverse drug reaction

KW - anxiety

KW - Article

KW - auricular therapy

KW - cancer chemotherapy

KW - cancer patient

KW - chemotherapy induced nausea and vomiting

KW - depression

KW - human

KW - randomized controlled trial (topic)

KW - systematic review

KW - therapy

KW - therapy effect

KW - treatment duration

UR - http://www.scopus.com/inward/record.url?scp=84916213248&partnerID=8YFLogxK

U2 - 10.1155/2014/430796

DO - 10.1155/2014/430796

M3 - Article

VL - 2014

SP - 1

EP - 18

JO - Evidence-Based Complementary and Alternative Medicine

JF - Evidence-Based Complementary and Alternative Medicine

SN - 1741-427X

M1 - 430796

ER -