Development and validation of an evidence-based acupressure intervention for fatigue-insomnia-depression symptom cluster in breast cancer survivors

Alison Wang, Jing-Yu Tan, Isabella Zhao, Mary Janice Polotan, Sabina Eliseeva

Research output: Contribution to journalMeeting Abstractpeer-review

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Abstract

Introduction
To develop an evidence-based acupoint stimulation intervention protocol that can be used in a Phase II randomized control trial (RCT) for Fatigueinsomnia-depression symptom cluster (FIDSC) management in breast cancer survivors .

Methods
The acupoint stimulation intervention protocol, including a true and a placebo intervention, was developed under the guidance of The MRC framework, which includes the procedures of identifying the existing evidence base (systematic reviews), relevant Traditional Chinese Medicine theories and practice standards of acupressure, and modelling the scientific and practical appropriateness of the intervention protocol via a panel of seven experts. The experts' consensus level was evaluated by content validity index (CVI).

Results
Acupoint formula, modality, technique, intensity and frequency of the acupoint stimulation were determined for both the true and placebo acupoint stimulation intervention. The true acupressure intervention was determined as a daily self-managed acupressure on specific acupoints for seven weeks. The placebo intervention followed the same frequency and duration of the true intervention group but using a light acupressure on non-acupoints. All the key components in the true and placebo intervention protocols were rated as content valid (CVI ≥0.86).

Conclusions
This study successfully developed and validated a research-informed, theory-driven and practically feasible body acupressure intervention protocol for managing FIDSC in breast cancer survivors.
Original languageEnglish
Pages (from-to)S48-S49
JournalSupportive Care in Cancer
Volume30
Issue numberSupplement 1
DOIs
Publication statusPublished - 1 Jun 2022

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