ECgMLP: A novel gated MLP model for enhanced endometrial cancer diagnosis

Md Alif Sheakh, Sami Azam, Mst Sazia Tahosin, Asif Karim, Sidratul Montaha, Kayes Uddin Fahim, Niusha Shafiabady, Mirjam Jonkman, Friso De Boer

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Abstract

Endometrial cancеr is the fourth fastеst-growing cancеr among women worldwide, affecting the uterus's lining. This research proposes a novel approach called ECgMLP for the automated diagnosis of endometrial cancer by analyzing histopathological images. Several preprocessing techniques are employed to increase the quality of the images, including normalization, Non-Local Means denoising, and alpha-beta enhancement. Effective segmentation is achieved through a combination of Otsu thresholding, morphological operations, distance transformations, and the watershed approach to identify major regions of interest. Through a sequence of blocks, the ECgMLP architecture processes input images to remove unimportant patterns. Model hyperparameters are improved via ablation research. The evaluations show a maximum accuracy of 99.26 % for identifying multi-class histopathological categories of endometrial tissue, which is higher than the previous best technique. The proposed model offers an automated, correct diagnosis, enhancing clinical processes. This proposition could be added to the current tools for finding endometrial cancer early, leading to better patient outcomes.

Original languageEnglish
Article number100181
Pages (from-to)1-18
Number of pages18
JournalComputer Methods and Programs in Biomedicine Update
Volume7
DOIs
Publication statusPublished - Jan 2025

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© 2025

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