Effect of pneumococcal vaccination on nasopharyngeal carriage of Streptococcus pneumoniae, Haemophilus influenzae, Moraxella catarrhalis, and Staphylococcus aureus in Fijian children

Eileen Dunne, J Manning, Fiona Russell, Roy M Robins-Browne, Edward (Kim) MULHOLLAND, Catherine Satzke

    Research output: Contribution to journalArticle

    Abstract

    The 7-valent pneumococcal conjugate vaccine (PCV7) reduces carriage of vaccine type Streptococcus pneumoniae but leads to replacement by nonvaccine serotypes and may affect carriage of other respiratory pathogens. We investigated nasopharyngeal carriage of S. pneumoniae, Haemophilus influenzae, Moraxella catarrhalis, and Staphylococcus aureus in Fijian infants participating in a pneumococcal vaccine trial using quantitative PCR. Vaccination did not affect pathogen carriage rates or densities, whereas significant differences between the two major ethnic groups were observed.
    Original languageEnglish
    Pages (from-to)1034-1038
    Number of pages5
    JournalJournal of Clinical Microbiology
    Volume50
    Issue number3
    DOIs
    Publication statusPublished - 2012

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