Efficient synthesis of quinazolines by the iron-catalyzed acceptorless dehydrogenative coupling of (2-aminophenyl)methanols and benzamides

Shi Qi Zhang, Yao Cui, Bin Guo, David J. Young, Ze Xu, Hong Xi Li

    Research output: Contribution to journalArticlepeer-review

    Abstract

    The acceptorless dehydrogenation coupling (ADC) of (2-aminophenyl)methanols with benzamides was achieved with catalytic FeCl2·4H2O in an efficient synthesis of quinazolines. This simple catalytic system is atom-economical, environmentally benign and suited to a variety of substrates.

    Original languageEnglish
    Article number131825
    Pages (from-to)1-8
    Number of pages8
    JournalTetrahedron
    Volume78
    DOIs
    Publication statusPublished - 8 Jan 2021

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