TY - JOUR
T1 - Epidemiology of antenatal depression in Africa
T2 - A systematic review and meta-analysis
AU - Dadi, Abel Fekadu
AU - Wolde, Haileab Fekadu
AU - Baraki, Adhanom Gebreegziabher
AU - Akalu, Temesgen Yihunie
N1 - Publisher Copyright:
© 2020 The Author(s).
Copyright:
Copyright 2020 Elsevier B.V., All rights reserved.
PY - 2020/4/28
Y1 - 2020/4/28
N2 - Background: Antenatal depression is a serious problem worldwide that has devastating consequences not only for the mother but also for the child and family. The pooled evidence regarding the prevalence and associated factors of antenatal depression is rare in Africa. Hence this review aimed to investigate the prevalence and associated factors of antenatal depression in Africa. Methods: We searched CINHAL, MEDLINE, PsycINFO, Psychiatry online, PubMed, SCOPES, and Emcare databases for English written observational studies conducted in Africa from 2007 to 2018.Quality of studies was assessed using the Newcastle Ottawa Scale (NOS), and studies with good quality were included in the final review. Heterogeneity across studies was assessed using the I 2 and Higgins test. Publication bias was checked using Funnel plot symmetry, and Egger's regression test and adjustment was made by using Duval and Tweedie's Trim and Fill analysis. A random effect Meta-analysis was employed to determine the pooled estimates with 95% confidence interval (CI). Stata 14 was used for analysis. The review protocol has been registered in PROSPERO number CRD42018106717. Result: Of the 175 studies identified, 28 studies with an overall sample size of 17,938 were included. According to the random effect model following trim and fill analysis, the pooled prevalence of antenatal depression in Africa was 26.3% (95%CI: 22.2, 30.4%). Economic difficulties [POR = 1.87;95%CI:1.25,2.78,I 2 = 88.1%], unfavorable marital condition [POR = 4.17;95% CI:1.75, 9.94, I 2 = 81.2%], poor support from relatives [POR = 1.36;95% CI:1.18, 1.56, I 2 = 78.0%], bad obstetric history [POR = 2.30;95% CI:1.81, 2.92), I 2 = 81.7%], and history of mental health problem [POR = 2.97; 95% CI:1.74, 5.06, I 2 = 92.0%]were the factors associated with antenatal depression. Conclusion: The prevalence of antenatal depression is high in Africa, which showed that one in four pregnant women had depression. Pregnant mothers who had economic difficulties, bad obstetric history, poor support from relatives, previous mental health problems, and unfavorable marital conditions were at higher risk of antenatal depression. Therefore these factors should be considered while designing mental health care services for pregnant mothers.
AB - Background: Antenatal depression is a serious problem worldwide that has devastating consequences not only for the mother but also for the child and family. The pooled evidence regarding the prevalence and associated factors of antenatal depression is rare in Africa. Hence this review aimed to investigate the prevalence and associated factors of antenatal depression in Africa. Methods: We searched CINHAL, MEDLINE, PsycINFO, Psychiatry online, PubMed, SCOPES, and Emcare databases for English written observational studies conducted in Africa from 2007 to 2018.Quality of studies was assessed using the Newcastle Ottawa Scale (NOS), and studies with good quality were included in the final review. Heterogeneity across studies was assessed using the I 2 and Higgins test. Publication bias was checked using Funnel plot symmetry, and Egger's regression test and adjustment was made by using Duval and Tweedie's Trim and Fill analysis. A random effect Meta-analysis was employed to determine the pooled estimates with 95% confidence interval (CI). Stata 14 was used for analysis. The review protocol has been registered in PROSPERO number CRD42018106717. Result: Of the 175 studies identified, 28 studies with an overall sample size of 17,938 were included. According to the random effect model following trim and fill analysis, the pooled prevalence of antenatal depression in Africa was 26.3% (95%CI: 22.2, 30.4%). Economic difficulties [POR = 1.87;95%CI:1.25,2.78,I 2 = 88.1%], unfavorable marital condition [POR = 4.17;95% CI:1.75, 9.94, I 2 = 81.2%], poor support from relatives [POR = 1.36;95% CI:1.18, 1.56, I 2 = 78.0%], bad obstetric history [POR = 2.30;95% CI:1.81, 2.92), I 2 = 81.7%], and history of mental health problem [POR = 2.97; 95% CI:1.74, 5.06, I 2 = 92.0%]were the factors associated with antenatal depression. Conclusion: The prevalence of antenatal depression is high in Africa, which showed that one in four pregnant women had depression. Pregnant mothers who had economic difficulties, bad obstetric history, poor support from relatives, previous mental health problems, and unfavorable marital conditions were at higher risk of antenatal depression. Therefore these factors should be considered while designing mental health care services for pregnant mothers.
KW - Africa
KW - Antenatal depression
KW - Associated factors
KW - Meta-analysis
KW - Systematic review
UR - http://www.scopus.com/inward/record.url?scp=85084169962&partnerID=8YFLogxK
U2 - 10.1186/s12884-020-02929-5
DO - 10.1186/s12884-020-02929-5
M3 - Article
C2 - 32345263
AN - SCOPUS:85084169962
VL - 20
SP - 1
EP - 13
JO - BMC Pregnancy and Childbirth
JF - BMC Pregnancy and Childbirth
SN - 1471-2393
IS - 1
M1 - 251
ER -