Estimating the total incidence of kidney failure in Australia including individuals who are not treated by dialysis or transplantation

Claire Sparke, Lynelle Moon, Frances Green, Timothy Mathew, Alan Cass, Steve Chadban, Jeremy Chapman, Wendy Hoy, S McDonald

    Research output: Contribution to journalArticleResearchpeer-review

    Abstract


    BACKGROUND: To date, incidence data for kidney failure in Australia have been available for only those who start renal replacement therapy (RRT). Information about the total incidence of kidney failure, including non-RRT-treated cases, is important to help understand the burden of kidney failure in the community and the characteristics of patients who die without receiving treatment.

    STUDY DESIGN:
     Data linkage study of national observational data sets.

    SETTING & PARTICIPANTS:
     All incident treated cases recorded in the Australia and New Zealand Dialysis and Transplant Registry (ANZDATA) probabilistically linked to incident untreated kidney failure cases derived from national death registration data for 2003-2007.

    PREDICTOR:
     Age, sex, and year.

    OUTCOMES: Kidney failure, a combination of incident RRT or death attributed to kidney failure (without RRT).

    MEASUREMENTS:
     Total incidence of kidney failure (treated and untreated) and treatment rates.

    RESULTS:
     There were 21,370 incident cases of kidney failure in 2003-2007. The incidence rate was 20.9/100,000 population (95% CI, 18.3-24.0) and was significantly higher among older people and males (26.1/100,000 population; 95% CI, 22.5-30.0) compared with females (17.0/100,000 population; 95% CI, 14.9-19.2). There were similars number of treated (10,949) and untreated (10,421) cases, but treatment rates were influenced highly by age. More than 90% of cases in all age groups between 5 and 60 years were treated, but this percentage decreased sharply for older people; only 4% of cases in persons 85 years or older were treated (ORs for no treatment of 115 [95% CI, 118-204] for men ≥80 years and 400 [95% CI, 301-531] for women ≥80 years compared with women who were <50 years).

    LIMITATIONS: Cross-sectional design, reliance on accurate coding of kidney failure in death registration data.

    CONCLUSIONS: Almost all Australians who develop kidney failure at younger than 60 years receive RRT, but treatment rates decrease substantially above that age.
    Original languageEnglish
    Pages (from-to)413-419
    Number of pages7
    JournalAmerican Journal of Kidney Diseases
    Volume61
    Issue number3
    DOIs
    Publication statusPublished - 2013

    Fingerprint

    Renal Insufficiency
    Dialysis
    Transplantation
    Incidence
    Renal Replacement Therapy
    Therapeutics
    Population
    Information Storage and Retrieval
    New Zealand
    Observational Studies
    Registries
    Age Groups
    Transplants

    Cite this

    Sparke, Claire ; Moon, Lynelle ; Green, Frances ; Mathew, Timothy ; Cass, Alan ; Chadban, Steve ; Chapman, Jeremy ; Hoy, Wendy ; McDonald, S. / Estimating the total incidence of kidney failure in Australia including individuals who are not treated by dialysis or transplantation. In: American Journal of Kidney Diseases. 2013 ; Vol. 61, No. 3. pp. 413-419.
    @article{1edfe9b699bb42948ddbcc5a9861b291,
    title = "Estimating the total incidence of kidney failure in Australia including individuals who are not treated by dialysis or transplantation",
    abstract = "BACKGROUND: To date, incidence data for kidney failure in Australia have been available for only those who start renal replacement therapy (RRT). Information about the total incidence of kidney failure, including non-RRT-treated cases, is important to help understand the burden of kidney failure in the community and the characteristics of patients who die without receiving treatment.STUDY DESIGN: Data linkage study of national observational data sets.SETTING & PARTICIPANTS: All incident treated cases recorded in the Australia and New Zealand Dialysis and Transplant Registry (ANZDATA) probabilistically linked to incident untreated kidney failure cases derived from national death registration data for 2003-2007.PREDICTOR: Age, sex, and year.OUTCOMES: Kidney failure, a combination of incident RRT or death attributed to kidney failure (without RRT).MEASUREMENTS: Total incidence of kidney failure (treated and untreated) and treatment rates.RESULTS: There were 21,370 incident cases of kidney failure in 2003-2007. The incidence rate was 20.9/100,000 population (95{\%} CI, 18.3-24.0) and was significantly higher among older people and males (26.1/100,000 population; 95{\%} CI, 22.5-30.0) compared with females (17.0/100,000 population; 95{\%} CI, 14.9-19.2). There were similars number of treated (10,949) and untreated (10,421) cases, but treatment rates were influenced highly by age. More than 90{\%} of cases in all age groups between 5 and 60 years were treated, but this percentage decreased sharply for older people; only 4{\%} of cases in persons 85 years or older were treated (ORs for no treatment of 115 [95{\%} CI, 118-204] for men ≥80 years and 400 [95{\%} CI, 301-531] for women ≥80 years compared with women who were <50 years).LIMITATIONS: Cross-sectional design, reliance on accurate coding of kidney failure in death registration data.CONCLUSIONS: Almost all Australians who develop kidney failure at younger than 60 years receive RRT, but treatment rates decrease substantially above that age.",
    author = "Claire Sparke and Lynelle Moon and Frances Green and Timothy Mathew and Alan Cass and Steve Chadban and Jeremy Chapman and Wendy Hoy and S McDonald",
    year = "2013",
    doi = "10.1053/j.ajkd.2012.10.012",
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    Estimating the total incidence of kidney failure in Australia including individuals who are not treated by dialysis or transplantation. / Sparke, Claire; Moon, Lynelle; Green, Frances; Mathew, Timothy; Cass, Alan; Chadban, Steve; Chapman, Jeremy; Hoy, Wendy; McDonald, S.

    In: American Journal of Kidney Diseases, Vol. 61, No. 3, 2013, p. 413-419.

    Research output: Contribution to journalArticleResearchpeer-review

    TY - JOUR

    T1 - Estimating the total incidence of kidney failure in Australia including individuals who are not treated by dialysis or transplantation

    AU - Sparke, Claire

    AU - Moon, Lynelle

    AU - Green, Frances

    AU - Mathew, Timothy

    AU - Cass, Alan

    AU - Chadban, Steve

    AU - Chapman, Jeremy

    AU - Hoy, Wendy

    AU - McDonald, S

    PY - 2013

    Y1 - 2013

    N2 - BACKGROUND: To date, incidence data for kidney failure in Australia have been available for only those who start renal replacement therapy (RRT). Information about the total incidence of kidney failure, including non-RRT-treated cases, is important to help understand the burden of kidney failure in the community and the characteristics of patients who die without receiving treatment.STUDY DESIGN: Data linkage study of national observational data sets.SETTING & PARTICIPANTS: All incident treated cases recorded in the Australia and New Zealand Dialysis and Transplant Registry (ANZDATA) probabilistically linked to incident untreated kidney failure cases derived from national death registration data for 2003-2007.PREDICTOR: Age, sex, and year.OUTCOMES: Kidney failure, a combination of incident RRT or death attributed to kidney failure (without RRT).MEASUREMENTS: Total incidence of kidney failure (treated and untreated) and treatment rates.RESULTS: There were 21,370 incident cases of kidney failure in 2003-2007. The incidence rate was 20.9/100,000 population (95% CI, 18.3-24.0) and was significantly higher among older people and males (26.1/100,000 population; 95% CI, 22.5-30.0) compared with females (17.0/100,000 population; 95% CI, 14.9-19.2). There were similars number of treated (10,949) and untreated (10,421) cases, but treatment rates were influenced highly by age. More than 90% of cases in all age groups between 5 and 60 years were treated, but this percentage decreased sharply for older people; only 4% of cases in persons 85 years or older were treated (ORs for no treatment of 115 [95% CI, 118-204] for men ≥80 years and 400 [95% CI, 301-531] for women ≥80 years compared with women who were <50 years).LIMITATIONS: Cross-sectional design, reliance on accurate coding of kidney failure in death registration data.CONCLUSIONS: Almost all Australians who develop kidney failure at younger than 60 years receive RRT, but treatment rates decrease substantially above that age.

    AB - BACKGROUND: To date, incidence data for kidney failure in Australia have been available for only those who start renal replacement therapy (RRT). Information about the total incidence of kidney failure, including non-RRT-treated cases, is important to help understand the burden of kidney failure in the community and the characteristics of patients who die without receiving treatment.STUDY DESIGN: Data linkage study of national observational data sets.SETTING & PARTICIPANTS: All incident treated cases recorded in the Australia and New Zealand Dialysis and Transplant Registry (ANZDATA) probabilistically linked to incident untreated kidney failure cases derived from national death registration data for 2003-2007.PREDICTOR: Age, sex, and year.OUTCOMES: Kidney failure, a combination of incident RRT or death attributed to kidney failure (without RRT).MEASUREMENTS: Total incidence of kidney failure (treated and untreated) and treatment rates.RESULTS: There were 21,370 incident cases of kidney failure in 2003-2007. The incidence rate was 20.9/100,000 population (95% CI, 18.3-24.0) and was significantly higher among older people and males (26.1/100,000 population; 95% CI, 22.5-30.0) compared with females (17.0/100,000 population; 95% CI, 14.9-19.2). There were similars number of treated (10,949) and untreated (10,421) cases, but treatment rates were influenced highly by age. More than 90% of cases in all age groups between 5 and 60 years were treated, but this percentage decreased sharply for older people; only 4% of cases in persons 85 years or older were treated (ORs for no treatment of 115 [95% CI, 118-204] for men ≥80 years and 400 [95% CI, 301-531] for women ≥80 years compared with women who were <50 years).LIMITATIONS: Cross-sectional design, reliance on accurate coding of kidney failure in death registration data.CONCLUSIONS: Almost all Australians who develop kidney failure at younger than 60 years receive RRT, but treatment rates decrease substantially above that age.

    U2 - 10.1053/j.ajkd.2012.10.012

    DO - 10.1053/j.ajkd.2012.10.012

    M3 - Article

    VL - 61

    SP - 413

    EP - 419

    JO - American Journal of Kidney Diseases

    JF - American Journal of Kidney Diseases

    SN - 0272-6386

    IS - 3

    ER -