TY - JOUR
T1 - Evidence of a Major Reservoir of Non-Malarial Febrile Diseases in Malaria-Endemic Regions of Bangladesh
AU - Swoboda, Paul
AU - Fuehrer, Hans-Peter
AU - Ley, Benedikt
AU - Starzengruber, Peter
AU - Ley-Thriemer, Kamala
AU - Jung, Mariella
AU - Matt, Julia
AU - Fally, Markus
AU - Mueller, Milena
AU - Reismann, Johannes
AU - Haque, Rashidul
AU - Khan, Wasif
AU - Noedl, Harald
PY - 2014
Y1 - 2014
N2 - In malaria-endemic regions any febrile case is likely to be classified as malaria based on presumptive diagnosis largely caused by a lack of diagnostic resources. A district-wide prevalence study assessing etiologies of fever in 659 patients recruited in rural and semi-urban areas of Bandarban district in southeastern Bangladesh revealed high proportions of seropositivity for selected infectious diseases (leptospirosis, typhoid fever) potentially being misdiagnosed as malaria because of similarities in the clinical presentation. In an area with point prevalences of more than 40% for malaria among fever cases, even higher seroprevalence rates of leptospirosis and typhoid fever provide evidence of a major persistent reservoir of these pathogens.
AB - In malaria-endemic regions any febrile case is likely to be classified as malaria based on presumptive diagnosis largely caused by a lack of diagnostic resources. A district-wide prevalence study assessing etiologies of fever in 659 patients recruited in rural and semi-urban areas of Bandarban district in southeastern Bangladesh revealed high proportions of seropositivity for selected infectious diseases (leptospirosis, typhoid fever) potentially being misdiagnosed as malaria because of similarities in the clinical presentation. In an area with point prevalences of more than 40% for malaria among fever cases, even higher seroprevalence rates of leptospirosis and typhoid fever provide evidence of a major persistent reservoir of these pathogens.
U2 - 10.4269/ajtmh.13-0487
DO - 10.4269/ajtmh.13-0487
M3 - Article
SN - 0002-9637
VL - 90
SP - 377
EP - 382
JO - American Journal of Tropical Medicine and Hygiene
JF - American Journal of Tropical Medicine and Hygiene
IS - 2
ER -