Follow-Up of Pulmonary Hypertension With Echocardiography

Leah M. Wright, Nathan Dwyer, David Celermajer, Len Kritharides, Thomas H. Marwick

Research output: Contribution to journalEditorialResearchpeer-review

Abstract

Individual patient response to effective therapies for pulmonary hypertension (PAH) is variable and difficult to quantify. Consequently, management decisions regarding initiation and continuation of therapy are highly dependent on the results of investigations. Registry data show that changes in cardiac index, mean right atrial pressure, and mean pulmonary artery pressure have the greatest influence on survival. It is recognized that pulmonary artery pressure (PASP) responses to PAH-specific drugs are heterogeneous. However, follow-up testing is strongly focused on assessing changes in PASP and functional status (6-min walk). The goals of therapy, which should be highlighted in follow-up imaging, include not only reduction of PASP, decrease in pulmonary vascular resistance, and improvements in right ventricular function, cardiac output, and tricuspid regurgitation. This paper reviews the echocardiographic follow-up of pulmonary hypertension, and especially focuses on right ventricular function—a major determinant of outcome, for which reliable echocardiographic assessment has become more feasible.

Original languageEnglish
Pages (from-to)733-746
Number of pages14
JournalJACC: Cardiovascular Imaging
Volume9
Issue number6
DOIs
Publication statusPublished - 2016

Fingerprint

Pulmonary Hypertension
Echocardiography
Pulmonary Artery
Pressure
Right Ventricular Function
Tricuspid Valve Insufficiency
Atrial Pressure
Cardiac Output
Vascular Resistance
Registries
Therapeutics
Survival
Pharmaceutical Preparations
4-S-(propionic acid)sulfidocyclophosphamide

Cite this

Wright, L. M., Dwyer, N., Celermajer, D., Kritharides, L., & Marwick, T. H. (2016). Follow-Up of Pulmonary Hypertension With Echocardiography. JACC: Cardiovascular Imaging, 9(6), 733-746. https://doi.org/10.1016/j.jcmg.2016.02.022
Wright, Leah M. ; Dwyer, Nathan ; Celermajer, David ; Kritharides, Len ; Marwick, Thomas H. / Follow-Up of Pulmonary Hypertension With Echocardiography. In: JACC: Cardiovascular Imaging. 2016 ; Vol. 9, No. 6. pp. 733-746.
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Wright, LM, Dwyer, N, Celermajer, D, Kritharides, L & Marwick, TH 2016, 'Follow-Up of Pulmonary Hypertension With Echocardiography', JACC: Cardiovascular Imaging, vol. 9, no. 6, pp. 733-746. https://doi.org/10.1016/j.jcmg.2016.02.022

Follow-Up of Pulmonary Hypertension With Echocardiography. / Wright, Leah M.; Dwyer, Nathan; Celermajer, David; Kritharides, Len; Marwick, Thomas H.

In: JACC: Cardiovascular Imaging, Vol. 9, No. 6, 2016, p. 733-746.

Research output: Contribution to journalEditorialResearchpeer-review

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