Friedel-Crafts cyclization of N,N-Dibenzylethylenediamines

Naseem H. Peerzada

    Research output: Contribution to journalComment/debate


    An efficient synthesis of substituted 1,2,3,4-tetrahydro-isoquinolines is described. N,N-dibenzylethylenediamines smoothly under go Friedel-Crafts cyclization in the presence of anhydrous aluminum chloride in decalin to give 1,2,3,4-tetrahydroisoquinolines.
    Original languageEnglish
    Pages (from-to)2533-2538
    Number of pages6
    JournalSynthetic Communications: an international journal for rapid communication of synthetic organic chemistry
    Issue number14
    Publication statusPublished - 1997

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