Gaps in tuberculosis care in West Sepik Province of Papua New Guinea

T. Kelebi, K. C. Takarinda, Robert Commons, B. Sissai, J. Yowei, M. Gale

    Research output: Contribution to journalArticleResearchpeer-review

    Abstract

    Setting: Papua New Guinea (PNG), a low-resource country with a high tuberculosis (TB) burden.

    Objective: To describe the characteristics, treatment outcomes and risk factors for unfavourable outcomes among patients registered for first-line tuberculosis (TB) treatment between 1 January 2014 and 31 December 2016 in West Sepik Province.

    Design: This was a retrospective cohort study of routinely collected programme data.

    Results: Of 1058 cases, 50.7% were male and 38.8% were aged <15 years; 43.1% were extrapulmonary TB cases and 280 (26.5%) were bacteriologically confirmed. No human immunodeficiency virus (HIV) status was recorded for 74.7% of cases. Of 1019 (96.3%) patients with a recorded outcome, 779 (76.4%) were favourable and 240 (23.6%) were unfavourable. On multivariable logistic regression, increasing age was associated with an increased odds of an unfavourable outcome (adjusted OR [aOR] 1.06 per every 5-year increase, 95%CI 1.02–1.11; P = 0.006) and being a retreatment case was associated with a reduced odds of an unfavourable outcome compared to new cases (aOR 0.54, 95%CI 0.31–0.93; P = 0.027).

    Conclusion: This study identified substantial gaps in TB care, including low rates of bacteriological diagnosis and HIV testing, and high rates of loss to follow-up, highlighting the need to strengthen TB control efforts, includingsupport for new cases.
    Original languageEnglish
    Pages (from-to)S68-S72
    Number of pages5
    JournalPublic Health Action
    Volume9
    Issue numberSupplement 1
    DOIs
    Publication statusPublished - 21 Sep 2019

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    Papua New Guinea
    Tuberculosis
    HIV
    Retreatment
    Cohort Studies
    Retrospective Studies
    Logistic Models

    Cite this

    Kelebi, T., Takarinda, K. C., Commons, R., Sissai, B., Yowei, J., & Gale, M. (2019). Gaps in tuberculosis care in West Sepik Province of Papua New Guinea. Public Health Action, 9(Supplement 1), S68-S72. https://doi.org/10.5588/pha.18.0057
    Kelebi, T. ; Takarinda, K. C. ; Commons, Robert ; Sissai, B. ; Yowei, J. ; Gale, M. / Gaps in tuberculosis care in West Sepik Province of Papua New Guinea. In: Public Health Action. 2019 ; Vol. 9, No. Supplement 1. pp. S68-S72.
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    abstract = "Setting: Papua New Guinea (PNG), a low-resource country with a high tuberculosis (TB) burden.Objective: To describe the characteristics, treatment outcomes and risk factors for unfavourable outcomes among patients registered for first-line tuberculosis (TB) treatment between 1 January 2014 and 31 December 2016 in West Sepik Province.Design: This was a retrospective cohort study of routinely collected programme data.Results: Of 1058 cases, 50.7{\%} were male and 38.8{\%} were aged <15 years; 43.1{\%} were extrapulmonary TB cases and 280 (26.5{\%}) were bacteriologically confirmed. No human immunodeficiency virus (HIV) status was recorded for 74.7{\%} of cases. Of 1019 (96.3{\%}) patients with a recorded outcome, 779 (76.4{\%}) were favourable and 240 (23.6{\%}) were unfavourable. On multivariable logistic regression, increasing age was associated with an increased odds of an unfavourable outcome (adjusted OR [aOR] 1.06 per every 5-year increase, 95{\%}CI 1.02–1.11; P = 0.006) and being a retreatment case was associated with a reduced odds of an unfavourable outcome compared to new cases (aOR 0.54, 95{\%}CI 0.31–0.93; P = 0.027).Conclusion: This study identified substantial gaps in TB care, including low rates of bacteriological diagnosis and HIV testing, and high rates of loss to follow-up, highlighting the need to strengthen TB control efforts, includingsupport for new cases.",
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    Kelebi, T, Takarinda, KC, Commons, R, Sissai, B, Yowei, J & Gale, M 2019, 'Gaps in tuberculosis care in West Sepik Province of Papua New Guinea', Public Health Action, vol. 9, no. Supplement 1, pp. S68-S72. https://doi.org/10.5588/pha.18.0057

    Gaps in tuberculosis care in West Sepik Province of Papua New Guinea. / Kelebi, T.; Takarinda, K. C.; Commons, Robert; Sissai, B.; Yowei, J.; Gale, M.

    In: Public Health Action, Vol. 9, No. Supplement 1, 21.09.2019, p. S68-S72.

    Research output: Contribution to journalArticleResearchpeer-review

    TY - JOUR

    T1 - Gaps in tuberculosis care in West Sepik Province of Papua New Guinea

    AU - Kelebi, T.

    AU - Takarinda, K. C.

    AU - Commons, Robert

    AU - Sissai, B.

    AU - Yowei, J.

    AU - Gale, M.

    PY - 2019/9/21

    Y1 - 2019/9/21

    N2 - Setting: Papua New Guinea (PNG), a low-resource country with a high tuberculosis (TB) burden.Objective: To describe the characteristics, treatment outcomes and risk factors for unfavourable outcomes among patients registered for first-line tuberculosis (TB) treatment between 1 January 2014 and 31 December 2016 in West Sepik Province.Design: This was a retrospective cohort study of routinely collected programme data.Results: Of 1058 cases, 50.7% were male and 38.8% were aged <15 years; 43.1% were extrapulmonary TB cases and 280 (26.5%) were bacteriologically confirmed. No human immunodeficiency virus (HIV) status was recorded for 74.7% of cases. Of 1019 (96.3%) patients with a recorded outcome, 779 (76.4%) were favourable and 240 (23.6%) were unfavourable. On multivariable logistic regression, increasing age was associated with an increased odds of an unfavourable outcome (adjusted OR [aOR] 1.06 per every 5-year increase, 95%CI 1.02–1.11; P = 0.006) and being a retreatment case was associated with a reduced odds of an unfavourable outcome compared to new cases (aOR 0.54, 95%CI 0.31–0.93; P = 0.027).Conclusion: This study identified substantial gaps in TB care, including low rates of bacteriological diagnosis and HIV testing, and high rates of loss to follow-up, highlighting the need to strengthen TB control efforts, includingsupport for new cases.

    AB - Setting: Papua New Guinea (PNG), a low-resource country with a high tuberculosis (TB) burden.Objective: To describe the characteristics, treatment outcomes and risk factors for unfavourable outcomes among patients registered for first-line tuberculosis (TB) treatment between 1 January 2014 and 31 December 2016 in West Sepik Province.Design: This was a retrospective cohort study of routinely collected programme data.Results: Of 1058 cases, 50.7% were male and 38.8% were aged <15 years; 43.1% were extrapulmonary TB cases and 280 (26.5%) were bacteriologically confirmed. No human immunodeficiency virus (HIV) status was recorded for 74.7% of cases. Of 1019 (96.3%) patients with a recorded outcome, 779 (76.4%) were favourable and 240 (23.6%) were unfavourable. On multivariable logistic regression, increasing age was associated with an increased odds of an unfavourable outcome (adjusted OR [aOR] 1.06 per every 5-year increase, 95%CI 1.02–1.11; P = 0.006) and being a retreatment case was associated with a reduced odds of an unfavourable outcome compared to new cases (aOR 0.54, 95%CI 0.31–0.93; P = 0.027).Conclusion: This study identified substantial gaps in TB care, including low rates of bacteriological diagnosis and HIV testing, and high rates of loss to follow-up, highlighting the need to strengthen TB control efforts, includingsupport for new cases.

    KW - rural health

    KW - loss to follow-up

    KW - HIV

    U2 - 10.5588/pha.18.0057

    DO - 10.5588/pha.18.0057

    M3 - Article

    VL - 9

    SP - S68-S72

    JO - Public Health Action

    JF - Public Health Action

    SN - 2220-8372

    IS - Supplement 1

    ER -

    Kelebi T, Takarinda KC, Commons R, Sissai B, Yowei J, Gale M. Gaps in tuberculosis care in West Sepik Province of Papua New Guinea. Public Health Action. 2019 Sep 21;9(Supplement 1):S68-S72. https://doi.org/10.5588/pha.18.0057