Abstract
Objective: To describe the characteristics, treatment outcomes and risk factors for unfavourable outcomes among patients registered for first-line tuberculosis (TB) treatment between 1 January 2014 and 31 December 2016 in West Sepik Province.
Design: This was a retrospective cohort study of routinely collected programme data.
Results: Of 1058 cases, 50.7% were male and 38.8% were aged <15 years; 43.1% were extrapulmonary TB cases and 280 (26.5%) were bacteriologically confirmed. No human immunodeficiency virus (HIV) status was recorded for 74.7% of cases. Of 1019 (96.3%) patients with a recorded outcome, 779 (76.4%) were favourable and 240 (23.6%) were unfavourable. On multivariable logistic regression, increasing age was associated with an increased odds of an unfavourable outcome (adjusted OR [aOR] 1.06 per every 5-year increase, 95%CI 1.02–1.11; P = 0.006) and being a retreatment case was associated with a reduced odds of an unfavourable outcome compared to new cases (aOR 0.54, 95%CI 0.31–0.93; P = 0.027).
Conclusion: This study identified substantial gaps in TB care, including low rates of bacteriological diagnosis and HIV testing, and high rates of loss to follow-up, highlighting the need to strengthen TB control efforts, includingsupport for new cases.
| Original language | English |
|---|---|
| Pages (from-to) | S68-S72 |
| Number of pages | 5 |
| Journal | Public Health Action |
| Volume | 9 |
| Issue number | Supplement 1 |
| DOIs | |
| Publication status | Published - 21 Sep 2019 |
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Gaps in tuberculosis care in West Sepik Province of Papua New Guinea. / Kelebi, T.; Takarinda, K. C.; Commons, Robert; Sissai, B.; Yowei, J.; Gale, M.
In: Public Health Action, Vol. 9, No. Supplement 1, 21.09.2019, p. S68-S72.Research output: Contribution to journal › Article › Research › peer-review
TY - JOUR
T1 - Gaps in tuberculosis care in West Sepik Province of Papua New Guinea
AU - Kelebi, T.
AU - Takarinda, K. C.
AU - Commons, Robert
AU - Sissai, B.
AU - Yowei, J.
AU - Gale, M.
PY - 2019/9/21
Y1 - 2019/9/21
N2 - Setting: Papua New Guinea (PNG), a low-resource country with a high tuberculosis (TB) burden.Objective: To describe the characteristics, treatment outcomes and risk factors for unfavourable outcomes among patients registered for first-line tuberculosis (TB) treatment between 1 January 2014 and 31 December 2016 in West Sepik Province.Design: This was a retrospective cohort study of routinely collected programme data.Results: Of 1058 cases, 50.7% were male and 38.8% were aged <15 years; 43.1% were extrapulmonary TB cases and 280 (26.5%) were bacteriologically confirmed. No human immunodeficiency virus (HIV) status was recorded for 74.7% of cases. Of 1019 (96.3%) patients with a recorded outcome, 779 (76.4%) were favourable and 240 (23.6%) were unfavourable. On multivariable logistic regression, increasing age was associated with an increased odds of an unfavourable outcome (adjusted OR [aOR] 1.06 per every 5-year increase, 95%CI 1.02–1.11; P = 0.006) and being a retreatment case was associated with a reduced odds of an unfavourable outcome compared to new cases (aOR 0.54, 95%CI 0.31–0.93; P = 0.027).Conclusion: This study identified substantial gaps in TB care, including low rates of bacteriological diagnosis and HIV testing, and high rates of loss to follow-up, highlighting the need to strengthen TB control efforts, includingsupport for new cases.
AB - Setting: Papua New Guinea (PNG), a low-resource country with a high tuberculosis (TB) burden.Objective: To describe the characteristics, treatment outcomes and risk factors for unfavourable outcomes among patients registered for first-line tuberculosis (TB) treatment between 1 January 2014 and 31 December 2016 in West Sepik Province.Design: This was a retrospective cohort study of routinely collected programme data.Results: Of 1058 cases, 50.7% were male and 38.8% were aged <15 years; 43.1% were extrapulmonary TB cases and 280 (26.5%) were bacteriologically confirmed. No human immunodeficiency virus (HIV) status was recorded for 74.7% of cases. Of 1019 (96.3%) patients with a recorded outcome, 779 (76.4%) were favourable and 240 (23.6%) were unfavourable. On multivariable logistic regression, increasing age was associated with an increased odds of an unfavourable outcome (adjusted OR [aOR] 1.06 per every 5-year increase, 95%CI 1.02–1.11; P = 0.006) and being a retreatment case was associated with a reduced odds of an unfavourable outcome compared to new cases (aOR 0.54, 95%CI 0.31–0.93; P = 0.027).Conclusion: This study identified substantial gaps in TB care, including low rates of bacteriological diagnosis and HIV testing, and high rates of loss to follow-up, highlighting the need to strengthen TB control efforts, includingsupport for new cases.
KW - rural health
KW - loss to follow-up
KW - HIV
U2 - 10.5588/pha.18.0057
DO - 10.5588/pha.18.0057
M3 - Article
VL - 9
SP - S68-S72
JO - Public Health Action
JF - Public Health Action
SN - 2220-8372
IS - Supplement 1
ER -