Genetic and epigenetic variation in vulvar cancer

Current research and future clinical practice

Rebekah E. Mcwhirter, James R. Marthick, Jacqueline A. Boyle, Joanne L. Dickinson

Research output: Contribution to journalArticleResearchpeer-review

Abstract

Vulvar cancer is a relatively rare gynaecological malignancy, the treatment of which is associated with significant patient morbidity. With reports that the incidence of vulvar cancer is increasing, there is a rising need for improved preventive, diagnostic and therapeutic tools. Recent advances within genetics and epigenetics present possible approaches for addressing this need, by contributing to the clarification of the aetiology of this disease, identifying screening and drug targets and introducing the potential for personalised treatments. This paper reviews the genetic and epigenetic research undertaken to date within vulvar cancer, evaluates its potential for clinical application and identifies directions for future research. 

Original languageEnglish
Pages (from-to)406-411
Number of pages6
JournalAustralian and New Zealand Journal of Obstetrics and Gynaecology
Volume54
Issue number5
DOIs
Publication statusPublished - 2014

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Vulvar Neoplasms
Epigenomics
Research
Genetic Research
Preclinical Drug Evaluations
Therapeutics
Morbidity
Incidence
Neoplasms

Cite this

Mcwhirter, Rebekah E. ; Marthick, James R. ; Boyle, Jacqueline A. ; Dickinson, Joanne L. / Genetic and epigenetic variation in vulvar cancer : Current research and future clinical practice. In: Australian and New Zealand Journal of Obstetrics and Gynaecology. 2014 ; Vol. 54, No. 5. pp. 406-411.
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Genetic and epigenetic variation in vulvar cancer : Current research and future clinical practice. / Mcwhirter, Rebekah E.; Marthick, James R.; Boyle, Jacqueline A.; Dickinson, Joanne L.

In: Australian and New Zealand Journal of Obstetrics and Gynaecology, Vol. 54, No. 5, 2014, p. 406-411.

Research output: Contribution to journalArticleResearchpeer-review

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