High burden of infectious disease and antibiotic use in early life in Australian Aboriginal communities

Will Cuningham, Jodie McVernon, Michael J. Lydeamore, Ross M. Andrews, Jonathan Carapetis, Therese Kearns, Danielle Clucas, Roslyn Gundjirryirr Dhurrkay, Steven Y.C. Tong, Patricia T. Campbell

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    Abstract

    Objective: To quantify the childhood infectious disease burden and antibiotic use in the Northern Territory’s East Arnhem region through synthesis and analysis of historical data resources.

    Methods: We combined primary health clinic data originally reported in three separate publications stemming from the East Arnhem Healthy Skin Project (Jan-01 to Sep-07). Common statistical techniques were used to explore the prevalence of infectious conditions and the seasonality of infections, and to measure rates of antibiotic use.

    Results: There was a high monthly prevalence of respiratory (mean: 32% [95% confidence interval (CI): 20%, 34%]) and skin (mean: 20% [95%CI: 19%, 22%]) infectious syndromes, with upper respiratory tract infections (mean: 29% [95%CI: 27%, 31%]) and skin sores (mean: 15% [95%CI: 14%, 17%]) the most common conditions. Antibiotics were frequently prescribed with 95% (95%CI: 91%, 97%) of children having received at least one antibiotic prescription by their first birthday, and 47% having received six antibiotic prescriptions; skin sores being a key driver.

    Conclusions: Early life infections drive high antibiotic prescribing rates in remote Aboriginal communities.

    Implications for public health: Eliminating skin disease could reduce antibiotic use by almost 20% in children under five years of age in this population.

    Original languageEnglish
    Pages (from-to)149-155
    Number of pages7
    JournalAustralian and New Zealand Journal of Public Health
    Volume43
    Issue number2
    Early online date6 Feb 2019
    DOIs
    Publication statusPublished - Apr 2019

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    Communicable Diseases
    Anti-Bacterial Agents
    Confidence Intervals
    Skin
    Prescriptions
    Infection
    Skin Diseases
    Respiratory Tract Infections
    Publications
    Public Health
    Health
    Population

    Cite this

    Cuningham, Will ; McVernon, Jodie ; Lydeamore, Michael J. ; Andrews, Ross M. ; Carapetis, Jonathan ; Kearns, Therese ; Clucas, Danielle ; Dhurrkay, Roslyn Gundjirryirr ; Tong, Steven Y.C. ; Campbell, Patricia T. / High burden of infectious disease and antibiotic use in early life in Australian Aboriginal communities. In: Australian and New Zealand Journal of Public Health. 2019 ; Vol. 43, No. 2. pp. 149-155.
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    abstract = "Objective: To quantify the childhood infectious disease burden and antibiotic use in the Northern Territory’s East Arnhem region through synthesis and analysis of historical data resources. Methods: We combined primary health clinic data originally reported in three separate publications stemming from the East Arnhem Healthy Skin Project (Jan-01 to Sep-07). Common statistical techniques were used to explore the prevalence of infectious conditions and the seasonality of infections, and to measure rates of antibiotic use. Results: There was a high monthly prevalence of respiratory (mean: 32{\%} [95{\%} confidence interval (CI): 20{\%}, 34{\%}]) and skin (mean: 20{\%} [95{\%}CI: 19{\%}, 22{\%}]) infectious syndromes, with upper respiratory tract infections (mean: 29{\%} [95{\%}CI: 27{\%}, 31{\%}]) and skin sores (mean: 15{\%} [95{\%}CI: 14{\%}, 17{\%}]) the most common conditions. Antibiotics were frequently prescribed with 95{\%} (95{\%}CI: 91{\%}, 97{\%}) of children having received at least one antibiotic prescription by their first birthday, and 47{\%} having received six antibiotic prescriptions; skin sores being a key driver. Conclusions: Early life infections drive high antibiotic prescribing rates in remote Aboriginal communities. Implications for public health: Eliminating skin disease could reduce antibiotic use by almost 20{\%} in children under five years of age in this population.",
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    High burden of infectious disease and antibiotic use in early life in Australian Aboriginal communities. / Cuningham, Will; McVernon, Jodie; Lydeamore, Michael J.; Andrews, Ross M.; Carapetis, Jonathan; Kearns, Therese; Clucas, Danielle; Dhurrkay, Roslyn Gundjirryirr; Tong, Steven Y.C.; Campbell, Patricia T.

    In: Australian and New Zealand Journal of Public Health, Vol. 43, No. 2, 04.2019, p. 149-155.

    Research output: Contribution to journalArticleResearchpeer-review

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    AU - McVernon, Jodie

    AU - Lydeamore, Michael J.

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    AU - Kearns, Therese

    AU - Clucas, Danielle

    AU - Dhurrkay, Roslyn Gundjirryirr

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    AU - Campbell, Patricia T.

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