High burden of invasive ?-haemolytic streptococcal infections in Fiji

Andrew Steer, A JENNEY, F Oppedisano, M BATZLOFF, J Hartas, J Passmore, F Russell, Joseph Kado, Jonathan Carapetis

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    We undertook a 5-year retrospective study of group A streptococcal (GAS) bacteraemia in Fiji, supplemented by a 9-month detailed retrospective study of ?-haemolytic streptococcal (BHS) infections. The all-age incidence of GAS bacteraemia over 5 years was 11.6/100 000. Indigenous Fijians were 4.7 times more likely to present with invasive BHS disease than people of other ethnicities, and 6.4 times more likely than Indo-Fijians. The case-fatality rate for invasive BHS infections was 28%. emm-typing was performed on 23 isolates: 17 different emm-types were found, and the emm-type profile was different from that found in industrialized nations. These data support the contentions that elevated rates of invasive BHS and GAS infections are widespread in developing countries, and that the profile of invasive organisms in these settings reflects a wide diversity of emm-types and a paucity of types typically found in industrialized countries. � 2007 Cambridge University Press.
    Original languageEnglish
    Pages (from-to)621-627
    Number of pages7
    JournalEpidemiology and Infection
    Issue number5
    Publication statusPublished - 2008


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