High burden of RSV hospitalization in very young children: A data linkage study

N. Homaira, J. L. Oei, K. A. Mallitt, M. E. Abdel-Latif, L. Hilder, B. Bajuk, K. Lui, M. Ferson, A. Nurkic, G. M. Chambers, W. Rawlinson, T. Snelling, A. Jaffe

    Research output: Contribution to journalArticle

    Abstract

    Linked administrative population data were used to estimate the burden of childhood respiratory syncytial virus (RSV) hospitalization in an Australian cohort aged <5 years. RSV-coded hospitalizations data were extracted for all children aged <5 years born in New South Wales (NSW), Australia between 2001 and 2010. Incidence was calculated as the total number of new episodes of RSV hospitalization divided by the child-years at risk. Mean cost per episode of RSV hospitalization was estimated using public hospital cost weights. The cohort comprised of 870 314 children. The population-based incidence/1000 child-years of RSV hospitalization for children aged <5 years was 4·9 with a rate of 25·6 in children aged <3 months. The incidence of RSV hospitalization (per 1000 child-years) was 11·0 for Indigenous children, 81·5 for children with bronchopulmonary dysplasia (BPD), 10·2 for preterm children with gestational age (GA) 32-36 weeks, 27·0 for children with GA 28-31 weeks, 39·0 for children with GA <28 weeks and 6·7 for term children with low birthweight. RSV hospitalization was associated with an average annual cost of more than AUD 9 million in NSW. RSV was associated with a substantial burden of childhood hospitalization specifically in children aged <3 months and in Indigenous children and children born preterm or with BPD.

    Original languageEnglish
    Pages (from-to)1612-1621
    Number of pages10
    JournalEpidemiology and Infection
    Volume144
    Issue number8
    DOIs
    Publication statusPublished - Jun 2016

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    Homaira, N., Oei, J. L., Mallitt, K. A., Abdel-Latif, M. E., Hilder, L., Bajuk, B., Lui, K., Ferson, M., Nurkic, A., Chambers, G. M., Rawlinson, W., Snelling, T., & Jaffe, A. (2016). High burden of RSV hospitalization in very young children: A data linkage study. Epidemiology and Infection, 144(8), 1612-1621. https://doi.org/10.1017/S0950268815003015