Abstract
Contrary to expectations, the high pressure (9 kbar, 30°C) mediated addition of allyltrimethylstannane (2) to α-amino aldehydes (1) proceeds via an anti - Felkin - Anh mode to provide predominantly (60-88%) syn homoallylic alcohols. The diastereoselectivity of this reaction is dependent on the amino aldehyde side chain.
| Original language | English |
|---|---|
| Pages (from-to) | 581-582 |
| Number of pages | 2 |
| Journal | Main Group Metal Chemistry |
| Volume | 20 |
| Issue number | 9 |
| DOIs | |
| Publication status | Published - 1 Sep 1997 |
| Externally published | Yes |
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Cite this
Cokley, T. M., Isaacs, N. S., McCluskey, A., & Young, D. J. (1997). High pressure allylstannane addition to α-amino aldehydes: Syn diastereoselectivity in the absence of chelation control. Main Group Metal Chemistry, 20(9), 581-582. https://doi.org/10.1515/MGMC.1997.20.9.581