Hospital Admission Patterns in Children with CAH: Admission Rates and Adrenal Crises Decline with Age

R. Louise Rushworth, Henrik Falhammar, Craig F. Munns, Ann M. Maguire, David J. Torpy

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    Objective: To examine patterns of hospitalisation for acute medical conditions in children with congenital adrenal hyperplasia (CAH). 

    Design: A retrospective study of hospitalisation using administrative data. 

    Setting: All hospitals in NSW, Australia. Patients. All patients admitted with CAH and a random sample of admissions in patients aged 0 to 18 years without adrenal insufficiency (AI). 

    Main Outcome Measures: Admissions and comorbidities by age and sex.

    Results: Of 573 admissions for medical problems in CAH children, 286 (49.9%) were in males, and 236 (41.2%) had a principal diagnosis of CAH or had an adrenal crisis (AC). 37 (6.5%) ACs were recorded. An infection was found in 43.5% () of the CAH patient admissions and 51.7% () of the non-AI group, . Children aged up to one year had the highest number of admissions () and six ACs (four in males). There were 21 ACs recorded for children aged 1–5 years. Older CAH children had fewer admissions and fewer ACs. No in-hospital deaths were recorded. 

    Conclusions: Admission for medical problems in CAH children declines with age. An AC was recorded in 6.5% of the admissions, with the majority of ACs occurring in the 1 to 5 years age group and there were no deaths.

    Original languageEnglish
    Article number5748264
    Pages (from-to)1-7
    Number of pages7
    JournalInternational Journal of Endocrinology
    Publication statusPublished - 2016


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