Despite marine fish being an important food resource for coastal communities, the amount of fish caught by small-scale fisheries is unsustainable at many locations. Fish consumers have a critical role in species conservation because they can choose responsibly and avoid consuming overexploited or endangered species. In this study, local human consumption patterns and local knowledge about groupers and sharks caught by small-scale local fisheries were investigated in a Brazilian coral reef complex. Fish consumers were interviewed in a fish market setting regarding their monthly fish consumption, knowledge of endangered species, and strategies they do to consume fish responsibly. Of the 126 local fish consumers, 94% and 76% reported to buying sharks and groupers, respectively, on a monthly basis. The main strategies they used to consume fish responsibly were 1) getting fishmonger's advice and 2) buying fish on reliable fish markets. Our findings are important to understanding fish consumption preferences, which can contribute to the implementation of educational initiatives aiming to raise consumers' awareness regarding responsible consumption.