@article{54c3d5e4f4a24ec69e515ff7e6277290,
title = "Impact of Results of a Rapid Staphylococcus aureus Diagnostic Test on Prescribing of Antibiotics for Patients with Clustered Gram-Positive Cocci in Blood Cultures",
abstract = "In tropical northern Australia, approximately 20% of Staphylococcus aureus bacteremia is caused by methicillin-resistant Staphylococcus aureus (MRSA). We prospectively evaluated the impact on clinician antibiotic prescribing of the results obtained from performing the GeneXpert MRSA/SA test on 151 positive blood cultures with clustered Gram-positive cocci. The GeneXpert result led to earlier appropriate prescription of vancomycin for 54% of patients with MRSA; 25% of patients avoided vancomycin, and 16% of patients had all antibiotics ceased. ",
keywords = "antibiotic agent, cefazolin, flucloxacillin, meropenem, piperacillin plus tazobactam, teicoplanin, timentin, vancomycin, adult, aged, analytical parameters, article, bacterium isolate, blood culture, clinical decision making, controlled study, diagnostic kit, diagnostic test, female, Gram positive cocci, human, major clinical study, male, methicillin resistant Staphylococcus aureus, nonhuman, prescription, priority journal, prospective study, sensitivity and specificity, species differentiation, staphylococcal bacteremia, Staphylococcus aureus, Adult, Aged, Anti-Bacterial Agents, Australia, Bacteremia, Bacteriological Techniques, Blood, Diagnostic Tests, Routine, Drug Utilization, Female, Humans, Male, Middle Aged, Prescriptions, Prospective Studies, Staphylococcal Infections, Posibacteria",
author = "J Davies and Claire Gordon and Steven Tong and Robert Baird and Joshua Davis",
year = "2012",
doi = "10.1128/JCM.06773-11",
language = "English",
volume = "50",
pages = "2056--2058",
journal = "Journal of Clinical Microbiology",
issn = "0095-1137",
publisher = "American Society for Microbiology",
number = "6",
}