Implementation of POCT in the diabetic clinic in a large hospital

D Tanyanyiwa, C Dandara, Sindeep Amrat Bhana, B Pauly, F Marule, M Ramokoka, P Bwititi, Ezekiel (Uba) Nwose, B Nkosi

    Research output: Contribution to journalArticleResearchpeer-review

    Abstract

    Aim: Point-of-care testing (POCT) is gaining renewed interest, especially in resource-limiting primary health care, due to rise in prevalence of communicable and non-communicable diseases hence POCT needs continuous appraisal.


    Methods: Random glucose and glycated haemoglobin (HbA1c) were measured in 104 diabetic patients using standard laboratory multichannel analyzer 917. The utility of venous blood compared to capillary blood in measuring HbA1c was evaluated in a subset of 20 patients using a POCT device, DCA Vantage. Lastly, the POCT was validated against the laboratory multichannel analyser 917, in measurement of HbA1c in a second subset of 46 patients.


    Results: Random blood glucose levels and HbA1c levels moderately correlated (r2 = 0.56; p < 0.0001). Random glucose tests showed that 41% of the patients had poor glycaemic control while HbA1c showed 74%. Venous and capillary blood in HbA1c showed strong correlation (r2 = 0.89440; p < 0.001. There was also strong correlation (r = 0.9802; p < 0.0001) in HbA1c measured using the DCA Vantage and the standard laboratory analyser, Multichannel Analyser 917.


    Conclusion: Venous or capillary blood can be used in POCT for HbA1c. POCT is ideal for monitoring glucose control and management of diabetes in resource-limited countries such as South Africa.

    Original languageEnglish
    Pages (from-to)902-907
    Number of pages6
    JournalAfrican Health Sciences
    Volume15
    Issue number3
    DOIs
    Publication statusPublished - 2015

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    Glucose
    Glycosylated Hemoglobin A
    South Africa
    Blood Glucose
    Primary Health Care
    Point-of-Care Testing
    Equipment and Supplies

    Cite this

    Tanyanyiwa, D., Dandara, C., Bhana, S. A., Pauly, B., Marule, F., Ramokoka, M., ... Nkosi, B. (2015). Implementation of POCT in the diabetic clinic in a large hospital. African Health Sciences, 15(3), 902-907. https://doi.org/10.4314/ahs.v15i3.26
    Tanyanyiwa, D ; Dandara, C ; Bhana, Sindeep Amrat ; Pauly, B ; Marule, F ; Ramokoka, M ; Bwititi, P ; Nwose, Ezekiel (Uba) ; Nkosi, B. / Implementation of POCT in the diabetic clinic in a large hospital. In: African Health Sciences. 2015 ; Vol. 15, No. 3. pp. 902-907.
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    abstract = "Aim: Point-of-care testing (POCT) is gaining renewed interest, especially in resource-limiting primary health care, due to rise in prevalence of communicable and non-communicable diseases hence POCT needs continuous appraisal. Methods: Random glucose and glycated haemoglobin (HbA1c) were measured in 104 diabetic patients using standard laboratory multichannel analyzer 917. The utility of venous blood compared to capillary blood in measuring HbA1c was evaluated in a subset of 20 patients using a POCT device, DCA Vantage. Lastly, the POCT was validated against the laboratory multichannel analyser 917, in measurement of HbA1c in a second subset of 46 patients. Results: Random blood glucose levels and HbA1c levels moderately correlated (r2 = 0.56; p < 0.0001). Random glucose tests showed that 41{\%} of the patients had poor glycaemic control while HbA1c showed 74{\%}. Venous and capillary blood in HbA1c showed strong correlation (r2 = 0.89440; p < 0.001. There was also strong correlation (r = 0.9802; p < 0.0001) in HbA1c measured using the DCA Vantage and the standard laboratory analyser, Multichannel Analyser 917. Conclusion: Venous or capillary blood can be used in POCT for HbA1c. POCT is ideal for monitoring glucose control and management of diabetes in resource-limited countries such as South Africa.",
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    Tanyanyiwa, D, Dandara, C, Bhana, SA, Pauly, B, Marule, F, Ramokoka, M, Bwititi, P, Nwose, EU & Nkosi, B 2015, 'Implementation of POCT in the diabetic clinic in a large hospital', African Health Sciences, vol. 15, no. 3, pp. 902-907. https://doi.org/10.4314/ahs.v15i3.26

    Implementation of POCT in the diabetic clinic in a large hospital. / Tanyanyiwa, D; Dandara, C; Bhana, Sindeep Amrat; Pauly, B; Marule, F; Ramokoka, M; Bwititi, P; Nwose, Ezekiel (Uba); Nkosi, B.

    In: African Health Sciences, Vol. 15, No. 3, 2015, p. 902-907.

    Research output: Contribution to journalArticleResearchpeer-review

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    AU - Bhana, Sindeep Amrat

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    AU - Bwititi, P

    AU - Nwose, Ezekiel (Uba)

    AU - Nkosi, B

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    N2 - Aim: Point-of-care testing (POCT) is gaining renewed interest, especially in resource-limiting primary health care, due to rise in prevalence of communicable and non-communicable diseases hence POCT needs continuous appraisal. Methods: Random glucose and glycated haemoglobin (HbA1c) were measured in 104 diabetic patients using standard laboratory multichannel analyzer 917. The utility of venous blood compared to capillary blood in measuring HbA1c was evaluated in a subset of 20 patients using a POCT device, DCA Vantage. Lastly, the POCT was validated against the laboratory multichannel analyser 917, in measurement of HbA1c in a second subset of 46 patients. Results: Random blood glucose levels and HbA1c levels moderately correlated (r2 = 0.56; p < 0.0001). Random glucose tests showed that 41% of the patients had poor glycaemic control while HbA1c showed 74%. Venous and capillary blood in HbA1c showed strong correlation (r2 = 0.89440; p < 0.001. There was also strong correlation (r = 0.9802; p < 0.0001) in HbA1c measured using the DCA Vantage and the standard laboratory analyser, Multichannel Analyser 917. Conclusion: Venous or capillary blood can be used in POCT for HbA1c. POCT is ideal for monitoring glucose control and management of diabetes in resource-limited countries such as South Africa.

    AB - Aim: Point-of-care testing (POCT) is gaining renewed interest, especially in resource-limiting primary health care, due to rise in prevalence of communicable and non-communicable diseases hence POCT needs continuous appraisal. Methods: Random glucose and glycated haemoglobin (HbA1c) were measured in 104 diabetic patients using standard laboratory multichannel analyzer 917. The utility of venous blood compared to capillary blood in measuring HbA1c was evaluated in a subset of 20 patients using a POCT device, DCA Vantage. Lastly, the POCT was validated against the laboratory multichannel analyser 917, in measurement of HbA1c in a second subset of 46 patients. Results: Random blood glucose levels and HbA1c levels moderately correlated (r2 = 0.56; p < 0.0001). Random glucose tests showed that 41% of the patients had poor glycaemic control while HbA1c showed 74%. Venous and capillary blood in HbA1c showed strong correlation (r2 = 0.89440; p < 0.001. There was also strong correlation (r = 0.9802; p < 0.0001) in HbA1c measured using the DCA Vantage and the standard laboratory analyser, Multichannel Analyser 917. Conclusion: Venous or capillary blood can be used in POCT for HbA1c. POCT is ideal for monitoring glucose control and management of diabetes in resource-limited countries such as South Africa.

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    Tanyanyiwa D, Dandara C, Bhana SA, Pauly B, Marule F, Ramokoka M et al. Implementation of POCT in the diabetic clinic in a large hospital. African Health Sciences. 2015;15(3):902-907. https://doi.org/10.4314/ahs.v15i3.26